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The map label for this gene is argG [H]

Identifier: 188585551

GI number: 188585551

Start: 979555

End: 980769

Strand: Reverse

Name: argG [H]

Synonym: Nther_0923

Alternate gene names: 188585551

Gene position: 980769-979555 (Counterclockwise)

Preceding gene: 188585552

Following gene: 188585550

Centisome position: 30.98

GC content: 36.87

Gene sequence:

>1215_bases
ATGAGTAAGATTAACAAAGTAGTTTTAGCGTATTCCGGAGGACTGGACACATCTGTTGCCATTAAATGGATTCAAGAGCA
GTACGATTGTGAGGTTATTGCAATGATAGGTGATGTTGGTCAAAAAGAAGATGTAGAAGCTGCCGAACAGAAAGCTTATG
ATACCGGAGCTAGTAAGGTTTATGTAGAAAATTTGCAAGAGGAGTTTGTAACTGATTATATCTATCCCGCCATGAAAGCA
AATATTATGTACGAAGGTAAGTATTTACTTGGAACAGCTATTTGCAGACCACTATTGGGTAAAAAATTAGTTGAAATTGC
TTTACAGGAAAATGCTGATGCTATAGCTCATGGCTGTACTGGAAAGGGGAATGATCAGGTTAGGTTTGAAATGGCTGTTA
AAGCTATGGCGCCTCATTTATCCATTATAGCGCCCTGGCGAGAATGGGATATCAAAGGCAGAGAAGATGCCGTTAAATAT
GCAAATAAATACGGAATTCCCGTACCTGTTACTAAAGAAATGCCTTACAGTATCGACAGAAATTTATTTCATTCCAGTTA
CGAAGGTGGTATTTTAGAAGATCCTAATTTTGAGCCGGATCAAAATATGTTCGTGATGACGACTGTCCCAGAACAAGCTC
CAGATGAACCCGAATATTTGGACTTAGATTTTGAACAAGGAATTCCTGTTAAATTGAATAACCAGGAACTATCACCAGTT
CAAATGATGGAGACTCTCAACGAAATTGGCGGGAAACATGGTATCGGAATAATAGATATAGTAGAAAACAGACTTCTTGG
TATGAAATCAAGAGGAGTATATGAAACCCCAGGTGGCACTCTTTTATATCACGCTAAAAAAGAACTAGAGTACCTGGTAT
TAGATAAGGATACCATGCACTTTAAAGAGGTAATTACTAATAAATATTCTGAACTAGTTTACAATGGTTTATGGTTTAGT
AGTTTAAAACAAGCTCTCGATGGTTTTGTTGAAAAAACTCAAAAACATCTATCAGGACATGTAAAACTAAAGTTATATAA
AGGCAATGTAATGATAGCCGGAAGATCAGCACCCTATAGCTTATACAGAGAAGACTTGGCCACCTTTGAAGAAGATGAAG
TTTATAATCAAAAAGATGCTGAAGGATTCATCAACTTATTTGGTCTCACTTTAACAACCGAAGGTATTGTCAAAAGAGGC
AAAGGAGGAGAATAA

Upstream 100 bases:

>100_bases
TCCCTATACACATGTAATCAATTATGTGTCATAGGGACGGGTTTTTTTATTATTAAATTAAATAAAAAATCAAATTCAAT
AACGAAAGGAGAAATTAATT

Downstream 100 bases:

>100_bases
CATTGTCAAAACTCTGGGGTGGAAGATTTTCAAAACAAACAGATCAACTAGTAGATGAATTTAATGCTTCCATCGAATTT
GATAACCGGTTAATATTTTA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSKINKVVLAYSGGLDTSVAIKWIQEQYDCEVIAMIGDVGQKEDVEAAEQKAYDTGASKVYVENLQEEFVTDYIYPAMKA
NIMYEGKYLLGTAICRPLLGKKLVEIALQENADAIAHGCTGKGNDQVRFEMAVKAMAPHLSIIAPWREWDIKGREDAVKY
ANKYGIPVPVTKEMPYSIDRNLFHSSYEGGILEDPNFEPDQNMFVMTTVPEQAPDEPEYLDLDFEQGIPVKLNNQELSPV
QMMETLNEIGGKHGIGIIDIVENRLLGMKSRGVYETPGGTLLYHAKKELEYLVLDKDTMHFKEVITNKYSELVYNGLWFS
SLKQALDGFVEKTQKHLSGHVKLKLYKGNVMIAGRSAPYSLYREDLATFEEDEVYNQKDAEGFINLFGLTLTTEGIVKRG
KGGE

Sequences:

>Translated_404_residues
MSKINKVVLAYSGGLDTSVAIKWIQEQYDCEVIAMIGDVGQKEDVEAAEQKAYDTGASKVYVENLQEEFVTDYIYPAMKA
NIMYEGKYLLGTAICRPLLGKKLVEIALQENADAIAHGCTGKGNDQVRFEMAVKAMAPHLSIIAPWREWDIKGREDAVKY
ANKYGIPVPVTKEMPYSIDRNLFHSSYEGGILEDPNFEPDQNMFVMTTVPEQAPDEPEYLDLDFEQGIPVKLNNQELSPV
QMMETLNEIGGKHGIGIIDIVENRLLGMKSRGVYETPGGTLLYHAKKELEYLVLDKDTMHFKEVITNKYSELVYNGLWFS
SLKQALDGFVEKTQKHLSGHVKLKLYKGNVMIAGRSAPYSLYREDLATFEEDEVYNQKDAEGFINLFGLTLTTEGIVKRG
KGGE
>Mature_403_residues
SKINKVVLAYSGGLDTSVAIKWIQEQYDCEVIAMIGDVGQKEDVEAAEQKAYDTGASKVYVENLQEEFVTDYIYPAMKAN
IMYEGKYLLGTAICRPLLGKKLVEIALQENADAIAHGCTGKGNDQVRFEMAVKAMAPHLSIIAPWREWDIKGREDAVKYA
NKYGIPVPVTKEMPYSIDRNLFHSSYEGGILEDPNFEPDQNMFVMTTVPEQAPDEPEYLDLDFEQGIPVKLNNQELSPVQ
MMETLNEIGGKHGIGIIDIVENRLLGMKSRGVYETPGGTLLYHAKKELEYLVLDKDTMHFKEVITNKYSELVYNGLWFSS
LKQALDGFVEKTQKHLSGHVKLKLYKGNVMIAGRSAPYSLYREDLATFEEDEVYNQKDAEGFINLFGLTLTTEGIVKRGK
GGE

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=401, Percent_Identity=45.6359102244389, Blast_Score=367, Evalue=1e-102,
Organism=Homo sapiens, GI16950633, Length=401, Percent_Identity=45.6359102244389, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1789563, Length=405, Percent_Identity=29.1358024691358, Blast_Score=144, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6324514, Length=419, Percent_Identity=41.0501193317422, Blast_Score=319, Evalue=6e-88,
Organism=Drosophila melanogaster, GI21358151, Length=394, Percent_Identity=44.1624365482233, Blast_Score=338, Evalue=5e-93,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45386; Mature: 45255

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKINKVVLAYSGGLDTSVAIKWIQEQYDCEVIAMIGDVGQKEDVEAAEQKAYDTGASKV
CCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHH
YVENLQEEFVTDYIYPAMKANIMYEGKYLLGTAICRPLLGKKLVEIALQENADAIAHGCT
HHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
GKGNDQVRFEMAVKAMAPHLSIIAPWREWDIKGREDAVKYANKYGIPVPVTKEMPYSIDR
CCCCCCEEHEEHHHHHCCCCEEEECCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
NLFHSSYEGGILEDPNFEPDQNMFVMTTVPEQAPDEPEYLDLDFEQGIPVKLNNQELSPV
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCEEECCCCCCHH
QMMETLNEIGGKHGIGIIDIVENRLLGMKSRGVYETPGGTLLYHAKKELEYLVLDKDTMH
HHHHHHHHHCCCCCCCHHEEHHHHHHCCCCCCCEECCCCEEEEEECCCCEEEEECCCHHH
FKEVITNKYSELVYNGLWFSSLKQALDGFVEKTQKHLSGHVKLKLYKGNVMIAGRSAPYS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEECCCCHH
LYREDLATFEEDEVYNQKDAEGFINLFGLTLTTEGIVKRGKGGE
HHHHHHHCCCHHHHCCCCCHHHHHHHHHHEEECHHHHCCCCCCC
>Mature Secondary Structure 
SKINKVVLAYSGGLDTSVAIKWIQEQYDCEVIAMIGDVGQKEDVEAAEQKAYDTGASKV
CCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCHH
YVENLQEEFVTDYIYPAMKANIMYEGKYLLGTAICRPLLGKKLVEIALQENADAIAHGCT
HHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
GKGNDQVRFEMAVKAMAPHLSIIAPWREWDIKGREDAVKYANKYGIPVPVTKEMPYSIDR
CCCCCCEEHEEHHHHHCCCCEEEECCHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
NLFHSSYEGGILEDPNFEPDQNMFVMTTVPEQAPDEPEYLDLDFEQGIPVKLNNQELSPV
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCEEECCCCCCHH
QMMETLNEIGGKHGIGIIDIVENRLLGMKSRGVYETPGGTLLYHAKKELEYLVLDKDTMH
HHHHHHHHHCCCCCCCHHEEHHHHHHCCCCCCCEECCCCEEEEEECCCCEEEEECCCHHH
FKEVITNKYSELVYNGLWFSSLKQALDGFVEKTQKHLSGHVKLKLYKGNVMIAGRSAPYS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEECCCCHH
LYREDLATFEEDEVYNQKDAEGFINLFGLTLTTEGIVKRGKGGE
HHHHHHHCCCHHHHCCCCCHHHHHHHHHHEEECHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA