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The map label for this gene is yycG [H]

Identifier: 188585545

GI number: 188585545

Start: 972175

End: 973659

Strand: Direct

Name: yycG [H]

Synonym: Nther_0917

Alternate gene names: 188585545

Gene position: 972175-973659 (Clockwise)

Preceding gene: 188585544

Following gene: 188585546

Centisome position: 30.71

GC content: 35.89

Gene sequence:

>1485_bases
ATGTCTTTACAAAAATTATTTAGGAAAAATAGCTTATTTTTACGATTGTTCTTGGCACTGTGGTTTCTTAGTGCTGGATT
GCTAATATTGACCGGTGTGTTTGTTAATAGAACTGTAGAGGCAGAATTTACAGAACTGGTGAGATCTAGTGAGATTGCAG
AACATGAGCAAATAACTGAATCAATTTCTGATATTTTAGCTCAGGAAGATAATTTTGCTAGTTCTTTACAGATGTCTATA
AACCATTTGGCTAGGACTCATAACAAGAGAATTATCTTGGAAGATTCTAATAGGGATGTAATTTTGGATACTGGTGAAGA
TCAACGAAGACATGGTCCTATGATGGATAGGGGGATGCATCAAGGTAGAGGCCCTGGCCGAGATCAAGAACACGGAGAAA
AGTCGGTAACAGAGTTTTACACTGATAGGGAGATAGAAGAAAACACATACCCTTTAACTATAAACGACGGTGAAAAGGGT
AGAGTTACTATCCTGTCTTTAGACAGAAAAGATGGTTTTTTTACTCCAGAAGAACTGGATTTCACCAGGCAGGTTACCAG
AAGTATCCTAGCTGGTAGTGGTATAGCTTTGTTATTGTCTGCTTTAATTAGTTTAATAGTGTCTTTGTCTATATCCAAAC
CTGTTAACAGTTTAAAAAGTACAGCTGAGCAGTTAAAGAAGGGTGAATTATCTCAAAGAGCAAATGTGGTAGGGCCTGAA
GAAATACAAGAATTATCAGTGAGTTTTAATGCCATGGCTGAGAATCTTGAGCATACAGATTTTATCAAGAAAAAGTTGAC
CCAGGATATTTCTCATGAATTGCGAAATCCCGTATCTTCTATAAAAGCCTATCTTGAAGCTTTCCAAGATGGTGTTTTGG
AAGTAGACGAGGATAATTTGAATAGTACAATGGAAGAGCTTACTCGTTTAGAGACTTTATCTAAACAGTTGCATCAGCTA
GCTTTAGTAGATTTCAAAGAGTACGAGCCTAAACTAGACTGGGTGAATTTAACGGATTTAGCTTATAAGCTAAAACACAC
TATTAGTAAACAGGTTTTAAAGTATAATATTGAATTCAGTTGTAACTTACCTGAAGAGGAAATATGGATTAAAGGAGATC
AAGAATTGTTATATGCTGCTATAAATAACCTGGTACAAAATGCGCTTAAATTCACAGATAATGGTGGGTTGATTGAAATG
GGCGTAGAAATAAAAGATGATACTAATCAAGTTATGATGTATGTTTCCGATAATGGTCAAGGGATTCCTCAAGATAAATT
ACCTTATATTTTTGAACGCTTTTATCAAGTCGAGGAATCCAGGACTAAAAAAGACCTGCCGAAAAATGATCCTAATTATA
GCTCTTGTGGAAGTGGAATAGGCTTGTCACTAGTCAAAGAATGGACTAAGGCTATGGGCGGTTATGTAGTGGTAGATTCC
CAGTTAGGCAAAGGAAGCACTTTTAAATTAATATTCCCTTATTAA

Upstream 100 bases:

>100_bases
TTTGCGAAGAAAAATTGAACAAAATCCTAAAAAACCTATTTTTATAAAAACTGTGTTTGGTGCCGGTTATCAATTTGGTA
AATTTTAAAGGAGTGCCTAA

Downstream 100 bases:

>100_bases
TCTTCACAAAATCTTCAAATCTTCCTGATATAGTTAAGATCAAATACGGATAAAACACAAACAAACAGGAGGTCGATTAA
CTATGTTTAAAAAAATCCTA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSLQKLFRKNSLFLRLFLALWFLSAGLLILTGVFVNRTVEAEFTELVRSSEIAEHEQITESISDILAQEDNFASSLQMSI
NHLARTHNKRIILEDSNRDVILDTGEDQRRHGPMMDRGMHQGRGPGRDQEHGEKSVTEFYTDREIEENTYPLTINDGEKG
RVTILSLDRKDGFFTPEELDFTRQVTRSILAGSGIALLLSALISLIVSLSISKPVNSLKSTAEQLKKGELSQRANVVGPE
EIQELSVSFNAMAENLEHTDFIKKKLTQDISHELRNPVSSIKAYLEAFQDGVLEVDEDNLNSTMEELTRLETLSKQLHQL
ALVDFKEYEPKLDWVNLTDLAYKLKHTISKQVLKYNIEFSCNLPEEEIWIKGDQELLYAAINNLVQNALKFTDNGGLIEM
GVEIKDDTNQVMMYVSDNGQGIPQDKLPYIFERFYQVEESRTKKDLPKNDPNYSSCGSGIGLSLVKEWTKAMGGYVVVDS
QLGKGSTFKLIFPY

Sequences:

>Translated_494_residues
MSLQKLFRKNSLFLRLFLALWFLSAGLLILTGVFVNRTVEAEFTELVRSSEIAEHEQITESISDILAQEDNFASSLQMSI
NHLARTHNKRIILEDSNRDVILDTGEDQRRHGPMMDRGMHQGRGPGRDQEHGEKSVTEFYTDREIEENTYPLTINDGEKG
RVTILSLDRKDGFFTPEELDFTRQVTRSILAGSGIALLLSALISLIVSLSISKPVNSLKSTAEQLKKGELSQRANVVGPE
EIQELSVSFNAMAENLEHTDFIKKKLTQDISHELRNPVSSIKAYLEAFQDGVLEVDEDNLNSTMEELTRLETLSKQLHQL
ALVDFKEYEPKLDWVNLTDLAYKLKHTISKQVLKYNIEFSCNLPEEEIWIKGDQELLYAAINNLVQNALKFTDNGGLIEM
GVEIKDDTNQVMMYVSDNGQGIPQDKLPYIFERFYQVEESRTKKDLPKNDPNYSSCGSGIGLSLVKEWTKAMGGYVVVDS
QLGKGSTFKLIFPY
>Mature_493_residues
SLQKLFRKNSLFLRLFLALWFLSAGLLILTGVFVNRTVEAEFTELVRSSEIAEHEQITESISDILAQEDNFASSLQMSIN
HLARTHNKRIILEDSNRDVILDTGEDQRRHGPMMDRGMHQGRGPGRDQEHGEKSVTEFYTDREIEENTYPLTINDGEKGR
VTILSLDRKDGFFTPEELDFTRQVTRSILAGSGIALLLSALISLIVSLSISKPVNSLKSTAEQLKKGELSQRANVVGPEE
IQELSVSFNAMAENLEHTDFIKKKLTQDISHELRNPVSSIKAYLEAFQDGVLEVDEDNLNSTMEELTRLETLSKQLHQLA
LVDFKEYEPKLDWVNLTDLAYKLKHTISKQVLKYNIEFSCNLPEEEIWIKGDQELLYAAINNLVQNALKFTDNGGLIEMG
VEIKDDTNQVMMYVSDNGQGIPQDKLPYIFERFYQVEESRTKKDLPKNDPNYSSCGSGIGLSLVKEWTKAMGGYVVVDSQ
LGKGSTFKLIFPY

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=265, Percent_Identity=29.811320754717, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=29.9342105263158, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=28.3898305084746, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=30.5220883534137, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=350, Percent_Identity=23.7142857142857, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=299, Percent_Identity=27.4247491638796, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787894, Length=308, Percent_Identity=26.2987012987013, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=238, Percent_Identity=28.1512605042017, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=27.0588235294118, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=352, Percent_Identity=23.0113636363636, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081816, Length=262, Percent_Identity=25.5725190839695, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.3418803418803, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789403, Length=324, Percent_Identity=24.3827160493827, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=306, Percent_Identity=22.8758169934641, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55987; Mature: 55856

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQKLFRKNSLFLRLFLALWFLSAGLLILTGVFVNRTVEAEFTELVRSSEIAEHEQITE
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SISDILAQEDNFASSLQMSINHLARTHNKRIILEDSNRDVILDTGEDQRRHGPMMDRGMH
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCHHHCCCCHHHCCC
QGRGPGRDQEHGEKSVTEFYTDREIEENTYPLTINDGEKGRVTILSLDRKDGFFTPEELD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHH
FTRQVTRSILAGSGIALLLSALISLIVSLSISKPVNSLKSTAEQLKKGELSQRANVVGPE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHH
EIQELSVSFNAMAENLEHTDFIKKKLTQDISHELRNPVSSIKAYLEAFQDGVLEVDEDNL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
NSTMEELTRLETLSKQLHQLALVDFKEYEPKLDWVNLTDLAYKLKHTISKQVLKYNIEFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHEECEEE
CNLPEEEIWIKGDQELLYAAINNLVQNALKFTDNGGLIEMGVEIKDDTNQVMMYVSDNGQ
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEEECCCCC
GIPQDKLPYIFERFYQVEESRTKKDLPKNDPNYSSCGSGIGLSLVKEWTKAMGGYVVVDS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCEEEEEC
QLGKGSTFKLIFPY
CCCCCCEEEEEECC
>Mature Secondary Structure 
SLQKLFRKNSLFLRLFLALWFLSAGLLILTGVFVNRTVEAEFTELVRSSEIAEHEQITE
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SISDILAQEDNFASSLQMSINHLARTHNKRIILEDSNRDVILDTGEDQRRHGPMMDRGMH
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCHHHCCCCHHHCCC
QGRGPGRDQEHGEKSVTEFYTDREIEENTYPLTINDGEKGRVTILSLDRKDGFFTPEELD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCCHHHH
FTRQVTRSILAGSGIALLLSALISLIVSLSISKPVNSLKSTAEQLKKGELSQRANVVGPE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHH
EIQELSVSFNAMAENLEHTDFIKKKLTQDISHELRNPVSSIKAYLEAFQDGVLEVDEDNL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEECCCHH
NSTMEELTRLETLSKQLHQLALVDFKEYEPKLDWVNLTDLAYKLKHTISKQVLKYNIEFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHEECEEE
CNLPEEEIWIKGDQELLYAAINNLVQNALKFTDNGGLIEMGVEIKDDTNQVMMYVSDNGQ
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCEEEEEECCCCC
GIPQDKLPYIFERFYQVEESRTKKDLPKNDPNYSSCGSGIGLSLVKEWTKAMGGYVVVDS
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCEEEEEC
QLGKGSTFKLIFPY
CCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]