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The map label for this gene is walR [H]

Identifier: 188585544

GI number: 188585544

Start: 971458

End: 972162

Strand: Direct

Name: walR [H]

Synonym: Nther_0916

Alternate gene names: 188585544

Gene position: 971458-972162 (Clockwise)

Preceding gene: 188585543

Following gene: 188585545

Centisome position: 30.69

GC content: 36.17

Gene sequence:

>705_bases
ATGAGTGAGAACACCAATTGTTACACTGTGTTAATCATAGAAGATGAACAGGGACTTGTGAAAGTTTTGAAAGCCTATTT
GGAGAAAGAAGGATACCAGGTCTATGCCTCTCACGATGGTTTAGCAGGATTAGAACTTTTTAAAAAACAAAATCCTGACA
TTGTGGTTTTAGATTTAATGCTTCCCAACATGTCAGGAGAAGAAATAGCCAGAAAAATCAGAAAAGAGCAAGAGACTCCA
ATTCTCATGTTAACTGCCAAGGGCAGTGAAGATGAGAAAATTACAGGTTTGGGAATAGGTGCAGATGATTATGTAGTAAA
GCCTGCCAGCCCAAGGGAAATAATAGCCAGGTTAAAGACAATTTTGCGAAGAGTAGGAAAAGAGCCTGGCAGAATACAAC
AAGAAATTATTACAGCAGGTGAAATCACCATTGATACTTTGGCTAAAAAAATTTATTTGCGAGGAACAGAGATTTCTTTA
ACTCAAACGGAATTTGATATTTTATCAACCCTGGCACTATATCCTAAAAAAGTGTTTTCTCGCGAAAACTTGGCTGATAG
AATATACGGTTATTTATGGGAAGGGGACTCCCGTACGATAGATACCCATATCAAGAATTTGCGAAGAAAAATTGAACAAA
ATCCTAAAAAACCTATTTTTATAAAAACTGTGTTTGGTGCCGGTTATCAATTTGGTAAATTTTAA

Upstream 100 bases:

>100_bases
ACAATTATAAATTTGAGTTAGTTAATGAAATTAAAATAAATCAAAGAGAAAATTATAACTGACATTAGGTTTTATGAAGT
CTTGATTGGAGGATTAAAAA

Downstream 100 bases:

>100_bases
AGGAGTGCCTAAATGTCTTTACAAAAATTATTTAGGAAAAATAGCTTATTTTTACGATTGTTCTTGGCACTGTGGTTTCT
TAGTGCTGGATTGCTAATAT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSENTNCYTVLIIEDEQGLVKVLKAYLEKEGYQVYASHDGLAGLELFKKQNPDIVVLDLMLPNMSGEEIARKIRKEQETP
ILMLTAKGSEDEKITGLGIGADDYVVKPASPREIIARLKTILRRVGKEPGRIQQEIITAGEITIDTLAKKIYLRGTEISL
TQTEFDILSTLALYPKKVFSRENLADRIYGYLWEGDSRTIDTHIKNLRRKIEQNPKKPIFIKTVFGAGYQFGKF

Sequences:

>Translated_234_residues
MSENTNCYTVLIIEDEQGLVKVLKAYLEKEGYQVYASHDGLAGLELFKKQNPDIVVLDLMLPNMSGEEIARKIRKEQETP
ILMLTAKGSEDEKITGLGIGADDYVVKPASPREIIARLKTILRRVGKEPGRIQQEIITAGEITIDTLAKKIYLRGTEISL
TQTEFDILSTLALYPKKVFSRENLADRIYGYLWEGDSRTIDTHIKNLRRKIEQNPKKPIFIKTVFGAGYQFGKF
>Mature_233_residues
SENTNCYTVLIIEDEQGLVKVLKAYLEKEGYQVYASHDGLAGLELFKKQNPDIVVLDLMLPNMSGEEIARKIRKEQETPI
LMLTAKGSEDEKITGLGIGADDYVVKPASPREIIARLKTILRRVGKEPGRIQQEIITAGEITIDTLAKKIYLRGTEISLT
QTEFDILSTLALYPKKVFSRENLADRIYGYLWEGDSRTIDTHIKNLRRKIEQNPKKPIFIKTVFGAGYQFGKF

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=42.1052631578947, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.0212765957447, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=40.7079646017699, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=32.3008849557522, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.5291479820628, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=33.1838565022422, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=36.5638766519824, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=32.3275862068966, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=33.6322869955157, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.0357142857143, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.7610619469027, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788550, Length=161, Percent_Identity=27.9503105590062, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=151, Percent_Identity=33.112582781457, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26525; Mature: 26394

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENTNCYTVLIIEDEQGLVKVLKAYLEKEGYQVYASHDGLAGLELFKKQNPDIVVLDLM
CCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCEEEEEEE
LPNMSGEEIARKIRKEQETPILMLTAKGSEDEKITGLGIGADDYVVKPASPREIIARLKT
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHH
ILRRVGKEPGRIQQEIITAGEITIDTLAKKIYLRGTEISLTQTEFDILSTLALYPKKVFS
HHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHEECCCEEEEEHHHHHHHHHHHHHHHHHHC
RENLADRIYGYLWEGDSRTIDTHIKNLRRKIEQNPKKPIFIKTVFGAGYQFGKF
CCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SENTNCYTVLIIEDEQGLVKVLKAYLEKEGYQVYASHDGLAGLELFKKQNPDIVVLDLM
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCEEEEEEE
LPNMSGEEIARKIRKEQETPILMLTAKGSEDEKITGLGIGADDYVVKPASPREIIARLKT
CCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCEECCCCHHHHHHHHHH
ILRRVGKEPGRIQQEIITAGEITIDTLAKKIYLRGTEISLTQTEFDILSTLALYPKKVFS
HHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHEECCCEEEEEHHHHHHHHHHHHHHHHHHC
RENLADRIYGYLWEGDSRTIDTHIKNLRRKIEQNPKKPIFIKTVFGAGYQFGKF
CCCHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA