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The map label for this gene is speE1 [H]

Identifier: 188585533

GI number: 188585533

Start: 956357

End: 958774

Strand: Direct

Name: speE1 [H]

Synonym: Nther_0905

Alternate gene names: 188585533

Gene position: 956357-958774 (Clockwise)

Preceding gene: 188585532

Following gene: 188585536

Centisome position: 30.21

GC content: 38.21

Gene sequence:

>2418_bases
ATGAGTTTAACTGTAAGACGATCAGAGGCTTTGATTAAGCTGTTTACAATATTAATTGGTATTACCGGAATGATGGGACA
GCTCCTTCTTTTAAGGGAGCTGTTAGTAACTTTTTACGGTAATGAATTAGTTATTGGGATTGTTATTGCCAATTGGGTGA
TTATGGAAGCTATCGGCAGTTTCTTTGGAGGTAAAATTAGCACTTCTCAAAGCTCAAAGCTTTGGTACTTTTTATTCCTG
GCCCTATATGCCCTGGTCTTACCAGCAGCTTTATATTTCTCACGGACTGCTGTAGTAATTTTATTTGATGTATTGCCTGG
TGAATCCATAAATATTTGGGAGCACTTCTTGTCTTCTATCTTAATACTTGTTTTTCCCGCCTTAATTCACGGGGCATTGT
ATCCCTTGGGGACAGCTATGTTAAAAGATGTGAGAGATTCGGCTAATGTAAATCTTTCAAGACAATCTGCCGGTGATGTG
TATATTTTAGAAAATCTAGGAACTTTAATTGGCGGTCTGTTTTTTACAATAATATTGGTTGACAAATACCACTCTTTTAC
CTTGGGGATAGCCATCACAGTAGTTCATTTAATGGCAGTAATAATGGGGACTACTTTTTTATCAAAAAGAGGGAAAGTAC
CGAGGAAAACGGAAGGGATCTATCTTGTATTGATAATCTTAGCTGTTGTGATAGTTTCCCCTTGGGGTTTTGATGTAGCC
GATACCTTGCACGAGTCTTCCTTAGAGCAGCAGTGGTGGGGAGCAAATATAGTCCATTATGAGAACACACCATATGGTAA
TATAACTACCCTGGAAAGTGATGGAGAATATACATTCTATTATGATGGACGTCCGGTTTTCACAGCCCCTGTCCCTGATA
TGGCCAGAATTAAAGACTTTATTCATGTGTCTGCAGCTTCTCACTCTTCACCTGAAGAAGTGTTAATGGTGGGAGGAGGT
ATGGGAGGCAGTATTGCTCAACTTCTTGAACATGAAGTTTCAGGATTAAAATATGTGGAACTAGATCCCAATTTACCTGG
AGTTGCCGGGAAATATCAAGTTTCACCGGTAAAAGAAGAATTGGAAGATCCCAGGGTAGAGCTAGAAATTACTGACGGCC
GCCAGTATCTGAGACAAACCGAAAACAACTATGATCTAATAGTCATGGGGTTCATTACTCCTGAAACTTTACAAACCAAT
CGCTTATTCACCGTTGAATTTTATGAATTGGTGGAGCAAACCTTGGCCGAAGGTGGTCTCCTAGCGTTTACTGCCCCTGG
CTCACGGGAATATATGAGCCGTGAAATGAAGCAATTAAATGCTTCCCTTTTTAACAGTGTTAGCCGTGTTTTTTCCGACA
TTAAGTTGATTCCCGGGGATGATAATATTTATCTTGCCTCTAATGATGAAATTAACTTAACCCCTCAAGTTCTATATCAA
AGACTTGAAGAACGGGATATTACTACTGAAATGATGACGGAAAGTTATTTGGAATATCGTCTTGATCCTGGAGTTAAGGA
GAAGATAACAAAGGATATAAAGACCATGGAAGTTCAACCAAACTTTGATTTCAATCCAAAAGGTTTCTTTTATACACTTC
AGCATTGGGGGACCATGTTTTCGCCTACTATGGTTCAATTCCTTGATAAGTTAGAGAGCTTTGAACCGATTTATTATATA
GCCCTGATAGCCCTTATATTCAGTGTTGTTTACATCGTTCCTCGGATCGCTCTAGTTTCGAGATACTCCTCTGATCTTAG
TATCCCCTTACTGATTGCCATTTTTATAAGCGGGATTATAGCTATGGCCTTTGATTTATTTATCATGTTTTCATTTCAGA
CTTTTTATGGTTCAATCTATAAAATGACGGGTTTTCTTCTGGCTTCATTCATGCTGGGAATGTTTTTAGGTGGTAATTGG
TCTGTTAGTAAACTGGTATCTACACAGACCAAAGAAATTCAAATCCGAACATTTAAGTTATGTGAACTGGTTTTAATTTT
ATTGATTTTTGGCCTAGGAAGTTTAATTTATGCAATGGGATCTTGGTCGAGAGTTTTACCTGATTTTATTTTTATAGGAA
TTTTTGGTATTTTAGCTGTTGTATCAGCTTTTCCCATAGGGGTTCAGTTCCCCCTTGCTGTAAGCATTTTGGAGGATGAT
TGGGACCCAAAATGTAAATCAACGGGGAATTTCGCTAAATCAATAAAAACGGAAAACTCAAAATTCGTCAGTACAGCTTC
AGCTTTATATGCTGCTGATTTACTGGGGGGTTGGATTTCTGGACTTGTGATATCCATGGTGTTATTCCCGGTTATCGGTT
TGGTAAATACTCTAATAGTTTTGGGTTTTATGAAGGTTGGCAGCTTGCTTTTATTATGTTTCTATCCTGTTAAATATGGG
ACTTCCAATCATTATTAA

Upstream 100 bases:

>100_bases
TCATTAAAAGAGATCACTTTTCCGTACATGAAATAAATTTAGAAGATGGAAAATGCGAAAACTGTGGATTAGATATCCCT
GGTGTTTGGAGCATCTAATC

Downstream 100 bases:

>100_bases
TAGTATTATTAAAGCTAATATTACCATGGTATCTAAAAAATTAGCAGTTGTGTAATCTAAATTTATAGTATTCCTAAGTA
AATTTACTCCATAGGTCATT

Product: Spermine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase 1; PAPT 1; SPDSY 1 [H]

Number of amino acids: Translated: 805; Mature: 804

Protein sequence:

>805_residues
MSLTVRRSEALIKLFTILIGITGMMGQLLLLRELLVTFYGNELVIGIVIANWVIMEAIGSFFGGKISTSQSSKLWYFLFL
ALYALVLPAALYFSRTAVVILFDVLPGESINIWEHFLSSILILVFPALIHGALYPLGTAMLKDVRDSANVNLSRQSAGDV
YILENLGTLIGGLFFTIILVDKYHSFTLGIAITVVHLMAVIMGTTFLSKRGKVPRKTEGIYLVLIILAVVIVSPWGFDVA
DTLHESSLEQQWWGANIVHYENTPYGNITTLESDGEYTFYYDGRPVFTAPVPDMARIKDFIHVSAASHSSPEEVLMVGGG
MGGSIAQLLEHEVSGLKYVELDPNLPGVAGKYQVSPVKEELEDPRVELEITDGRQYLRQTENNYDLIVMGFITPETLQTN
RLFTVEFYELVEQTLAEGGLLAFTAPGSREYMSREMKQLNASLFNSVSRVFSDIKLIPGDDNIYLASNDEINLTPQVLYQ
RLEERDITTEMMTESYLEYRLDPGVKEKITKDIKTMEVQPNFDFNPKGFFYTLQHWGTMFSPTMVQFLDKLESFEPIYYI
ALIALIFSVVYIVPRIALVSRYSSDLSIPLLIAIFISGIIAMAFDLFIMFSFQTFYGSIYKMTGFLLASFMLGMFLGGNW
SVSKLVSTQTKEIQIRTFKLCELVLILLIFGLGSLIYAMGSWSRVLPDFIFIGIFGILAVVSAFPIGVQFPLAVSILEDD
WDPKCKSTGNFAKSIKTENSKFVSTASALYAADLLGGWISGLVISMVLFPVIGLVNTLIVLGFMKVGSLLLLCFYPVKYG
TSNHY

Sequences:

>Translated_805_residues
MSLTVRRSEALIKLFTILIGITGMMGQLLLLRELLVTFYGNELVIGIVIANWVIMEAIGSFFGGKISTSQSSKLWYFLFL
ALYALVLPAALYFSRTAVVILFDVLPGESINIWEHFLSSILILVFPALIHGALYPLGTAMLKDVRDSANVNLSRQSAGDV
YILENLGTLIGGLFFTIILVDKYHSFTLGIAITVVHLMAVIMGTTFLSKRGKVPRKTEGIYLVLIILAVVIVSPWGFDVA
DTLHESSLEQQWWGANIVHYENTPYGNITTLESDGEYTFYYDGRPVFTAPVPDMARIKDFIHVSAASHSSPEEVLMVGGG
MGGSIAQLLEHEVSGLKYVELDPNLPGVAGKYQVSPVKEELEDPRVELEITDGRQYLRQTENNYDLIVMGFITPETLQTN
RLFTVEFYELVEQTLAEGGLLAFTAPGSREYMSREMKQLNASLFNSVSRVFSDIKLIPGDDNIYLASNDEINLTPQVLYQ
RLEERDITTEMMTESYLEYRLDPGVKEKITKDIKTMEVQPNFDFNPKGFFYTLQHWGTMFSPTMVQFLDKLESFEPIYYI
ALIALIFSVVYIVPRIALVSRYSSDLSIPLLIAIFISGIIAMAFDLFIMFSFQTFYGSIYKMTGFLLASFMLGMFLGGNW
SVSKLVSTQTKEIQIRTFKLCELVLILLIFGLGSLIYAMGSWSRVLPDFIFIGIFGILAVVSAFPIGVQFPLAVSILEDD
WDPKCKSTGNFAKSIKTENSKFVSTASALYAADLLGGWISGLVISMVLFPVIGLVNTLIVLGFMKVGSLLLLCFYPVKYG
TSNHY
>Mature_804_residues
SLTVRRSEALIKLFTILIGITGMMGQLLLLRELLVTFYGNELVIGIVIANWVIMEAIGSFFGGKISTSQSSKLWYFLFLA
LYALVLPAALYFSRTAVVILFDVLPGESINIWEHFLSSILILVFPALIHGALYPLGTAMLKDVRDSANVNLSRQSAGDVY
ILENLGTLIGGLFFTIILVDKYHSFTLGIAITVVHLMAVIMGTTFLSKRGKVPRKTEGIYLVLIILAVVIVSPWGFDVAD
TLHESSLEQQWWGANIVHYENTPYGNITTLESDGEYTFYYDGRPVFTAPVPDMARIKDFIHVSAASHSSPEEVLMVGGGM
GGSIAQLLEHEVSGLKYVELDPNLPGVAGKYQVSPVKEELEDPRVELEITDGRQYLRQTENNYDLIVMGFITPETLQTNR
LFTVEFYELVEQTLAEGGLLAFTAPGSREYMSREMKQLNASLFNSVSRVFSDIKLIPGDDNIYLASNDEINLTPQVLYQR
LEERDITTEMMTESYLEYRLDPGVKEKITKDIKTMEVQPNFDFNPKGFFYTLQHWGTMFSPTMVQFLDKLESFEPIYYIA
LIALIFSVVYIVPRIALVSRYSSDLSIPLLIAIFISGIIAMAFDLFIMFSFQTFYGSIYKMTGFLLASFMLGMFLGGNWS
VSKLVSTQTKEIQIRTFKLCELVLILLIFGLGSLIYAMGSWSRVLPDFIFIGIFGILAVVSAFPIGVQFPLAVSILEDDW
DPKCKSTGNFAKSIKTENSKFVSTASALYAADLLGGWISGLVISMVLFPVIGLVNTLIVLGFMKVGSLLLLCFYPVKYGT
SNHY

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG4262

COG function: function code R; Predicted spermidine synthase with an N-terminal membrane domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325326, Length=295, Percent_Identity=23.728813559322, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 89849; Mature: 89718

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS51006 SPERMIDINE_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTVRRSEALIKLFTILIGITGMMGQLLLLRELLVTFYGNELVIGIVIANWVIMEAIGS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
FFGGKISTSQSSKLWYFLFLALYALVLPAALYFSRTAVVILFDVLPGESINIWEHFLSSI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHH
LILVFPALIHGALYPLGTAMLKDVRDSANVNLSRQSAGDVYILENLGTLIGGLFFTIILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHH
DKYHSFTLGIAITVVHLMAVIMGTTFLSKRGKVPRKTEGIYLVLIILAVVIVSPWGFDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
DTLHESSLEQQWWGANIVHYENTPYGNITTLESDGEYTFYYDGRPVFTAPVPDMARIKDF
HHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEEEEECCEEEEECCCCCHHHHHHH
IHVSAASHSSPEEVLMVGGGMGGSIAQLLEHEVSGLKYVELDPNLPGVAGKYQVSPVKEE
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCHHHH
LEDPRVELEITDGRQYLRQTENNYDLIVMGFITPETLQTNRLFTVEFYELVEQTLAEGGL
CCCCCEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCCE
LAFTAPGSREYMSREMKQLNASLFNSVSRVFSDIKLIPGDDNIYLASNDEINLTPQVLYQ
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEECCCCCCCCHHHHHH
RLEERDITTEMMTESYLEYRLDPGVKEKITKDIKTMEVQPNFDFNPKGFFYTLQHWGTMF
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCEEEHHHCCCCC
SPTMVQFLDKLESFEPIYYIALIALIFSVVYIVPRIALVSRYSSDLSIPLLIAIFISGII
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AMAFDLFIMFSFQTFYGSIYKMTGFLLASFMLGMFLGGNWSVSKLVSTQTKEIQIRTFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHEEEHHHHH
CELVLILLIFGLGSLIYAMGSWSRVLPDFIFIGIFGILAVVSAFPIGVQFPLAVSILEDD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCC
WDPKCKSTGNFAKSIKTENSKFVSTASALYAADLLGGWISGLVISMVLFPVIGLVNTLIV
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFMKVGSLLLLCFYPVKYGTSNHY
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLTVRRSEALIKLFTILIGITGMMGQLLLLRELLVTFYGNELVIGIVIANWVIMEAIGS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
FFGGKISTSQSSKLWYFLFLALYALVLPAALYFSRTAVVILFDVLPGESINIWEHFLSSI
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHH
LILVFPALIHGALYPLGTAMLKDVRDSANVNLSRQSAGDVYILENLGTLIGGLFFTIILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHH
DKYHSFTLGIAITVVHLMAVIMGTTFLSKRGKVPRKTEGIYLVLIILAVVIVSPWGFDVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHH
DTLHESSLEQQWWGANIVHYENTPYGNITTLESDGEYTFYYDGRPVFTAPVPDMARIKDF
HHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEEEEECCEEEEECCCCCHHHHHHH
IHVSAASHSSPEEVLMVGGGMGGSIAQLLEHEVSGLKYVELDPNLPGVAGKYQVSPVKEE
HHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECCCHHHH
LEDPRVELEITDGRQYLRQTENNYDLIVMGFITPETLQTNRLFTVEFYELVEQTLAEGGL
CCCCCEEEEECCCHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHCCCE
LAFTAPGSREYMSREMKQLNASLFNSVSRVFSDIKLIPGDDNIYLASNDEINLTPQVLYQ
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEECCCCCCCCHHHHHH
RLEERDITTEMMTESYLEYRLDPGVKEKITKDIKTMEVQPNFDFNPKGFFYTLQHWGTMF
HHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCCCCCEEEHHHCCCCC
SPTMVQFLDKLESFEPIYYIALIALIFSVVYIVPRIALVSRYSSDLSIPLLIAIFISGII
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
AMAFDLFIMFSFQTFYGSIYKMTGFLLASFMLGMFLGGNWSVSKLVSTQTKEIQIRTFKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHEEEHHHHH
CELVLILLIFGLGSLIYAMGSWSRVLPDFIFIGIFGILAVVSAFPIGVQFPLAVSILEDD
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCC
WDPKCKSTGNFAKSIKTENSKFVSTASALYAADLLGGWISGLVISMVLFPVIGLVNTLIV
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGFMKVGSLLLLCFYPVKYGTSNHY
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]