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The map label for this gene is helD [H]

Identifier: 188585523

GI number: 188585523

Start: 943244

End: 945511

Strand: Reverse

Name: helD [H]

Synonym: Nther_0895

Alternate gene names: 188585523

Gene position: 945511-943244 (Counterclockwise)

Preceding gene: 188585528

Following gene: 188585522

Centisome position: 29.87

GC content: 33.02

Gene sequence:

>2268_bases
ATGTCGGAATTAAACCATCCAGATTATAATGAAGAGCTAGATCACTTAGAACGGACTAAAAGTTATATGGATCACTTCAT
AAATGAAATATCAAATAAACAACAACATTCTGCAGGTCAAATAAAGGAAGCTTATGAAATTTTGGATTTTCTCGACAGCA
GTCAAAGCTATATAACTATACTCGTTAATGCCAGATATTTAGACCATAGTACAGAAACTGTAGATAAAGTTAAACGGGCT
AAAAGCAGCCCTTACTTTAGTAGAATTGATTTTAGAGACCATCGTGATGAAGAGCCAAAAAGCTATTATATTGGTAAATT
ATCTTTATTTAAAGAAGATAACGAACCTGTAATCATAGATTGGCGATCACCAATTGCAAGTTTATATTACGAGGGGAGAT
TAGGCGAAGTATCTTACAAAGCCTATGAGGGAGAAATTACAGGTGAATTATCCCTGAAACGTCAATATACCATAGAAAAC
GAAGAGCTTCAGGATTTTTTTGATGTAGATATCACTACTACTGATGAACTTCTACAAGCCTCTCTCAGGGGAAGTGCCGA
TAACAAACTCAAAGATATAGTATCAACTATTCAGGCTGAACAAAATCAAGTTATCCGAGCAGATTTAAATAAACCCTTAA
TTGTTCAAGGGACAGCGGGTAGTGGTAAAACAACCATCGCTCTCCATAGGATAGCTTATTTAATATACACCTATGAAAAA
AGTTTTAATCCCGAGAATTTTATGATTATAGCCCCTAACAAATTATTTTTAGATTATATCTCCAATGTACTTCCAGATTT
AGGAGTTGAAGAAGCAAAACAAACCACATTTACTAGTTTTTGTTTTGAACTACTAGAAATAAAGGAACAACTAACTTTAC
AAGATTATAAATTATCTACACTACTTGAAAACTATGGCTTAACAAATTCCGAAAAAGATTTGATCAAATGGAGGGCTACC
TTCAAAGGTTCAATGACATTCAAGAAATTAATTGACAACTACATCTGCCAAATCGAACAAGATTTACTACCAAAAGAGGG
AATTGAATTAGAAGGTTATAGCATAATGAGCAAGGATGAAATCACAACAGCTTTTATGAAAGACTACTCTTACTTGCCTT
TATTTCAACGAATTGATCATATCAAGAAGAAATTATCAACAAGGGCAAAACAACAAAAATCATTAATTATTCAATCCATA
CAAAGTGAATACGAACAAAAGATTGATCAGGCCAGAAAATCTGAAAATCAAGAACTAGGTAGAAAAAATGCAGTAGCCTT
GATGGAAGAACGTGATCAAAAAATTGCAAGGGTTAAACAAGGAGCTGGAAAAATAGTTTCAAAATACACTAAACAATTTT
CCAAGAAAAACTATCTCACACATTACAAGAATTTAATGAAAACTCCATCTTTACTAAAGAAATTTTGTCCTGGAAATATA
GACGAAGAAAAAGTTAATTATTTATCTAAAACGGCTAAAACTTTATTTAAACATAAACAACTAGAATTAGAAGATTTAGC
ACCACTATTATATATAAAAGCAAATTTAGAAGGGTTCTCAACAGAAATTGAGAGCACAAATGTAATAATCGACGAAGCAC
AGGATTTCAGCTTGTTTCAACTTCACACTTTGAAATATGTCCTTAACACTAAAAACTTCACATTACTAGGTGACCTTTCC
CAAGGAATTCATGCATATAGAAGTATCAAAGATTGGGAAACAGTAAATAACCACATATTTGATAAAGAAGCCACTTCTCT
GTCATTACAGCAAAGCTATCGTACTACTGTAGAGATAATGAACCTGGCTAATCAAATTTTAGAACAAAGTGTAAATGACA
ATGTCCCTTTAGCAAGGCCAGTGGTACGCCACGGCAAAAAGCCCGAAAATAATGTGTATACTCAAATTCCTGACTTAATT
CAAGATCTAGCAGAAACAATTACAAAGCTACAATCTAGTAACTATAACTCCATTGCTATCATTGGGAAAACCATGAATGA
ATGTGAGACCATCAAACAGAATCTCCAGCAACAAAGAATTGACCTACCAGTATTAACGGGTTCAGAAGAGGATTATCAGG
CTGGAGCAGTAATAATACCATCTTATGCTACTAAGGGATTGGAATTTGATACAGCCTTAATTGTTAACCTAGAAGAAGAG
TATCAAAAAAATGAATTGGATGCCAAGCTTTTATACGTGTCAATGACACGGGCAATGCATGAATTGTATATATTTAATAT
CTTAGGTAAAATCGAATTTCTAAATTGA

Upstream 100 bases:

>100_bases
GATCGATCTATTTAATCTCTTTTTTTATCGATACGACTATGTTATATTAGGTTAATGTGTAAGTGTAGTTCCCTTCAAAC
AAAGTGGAAAGGAGTCAGAT

Downstream 100 bases:

>100_bases
CAAATAAAAACGGATTGAGATAAAATTAGCCATAGTGATACTTTTCACATTTACTGGCAGGTGTTCACGATGGTTTATAG
CAAAATAATATTAATTGTCC

Product: superfamily I DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MSELNHPDYNEELDHLERTKSYMDHFINEISNKQQHSAGQIKEAYEILDFLDSSQSYITILVNARYLDHSTETVDKVKRA
KSSPYFSRIDFRDHRDEEPKSYYIGKLSLFKEDNEPVIIDWRSPIASLYYEGRLGEVSYKAYEGEITGELSLKRQYTIEN
EELQDFFDVDITTTDELLQASLRGSADNKLKDIVSTIQAEQNQVIRADLNKPLIVQGTAGSGKTTIALHRIAYLIYTYEK
SFNPENFMIIAPNKLFLDYISNVLPDLGVEEAKQTTFTSFCFELLEIKEQLTLQDYKLSTLLENYGLTNSEKDLIKWRAT
FKGSMTFKKLIDNYICQIEQDLLPKEGIELEGYSIMSKDEITTAFMKDYSYLPLFQRIDHIKKKLSTRAKQQKSLIIQSI
QSEYEQKIDQARKSENQELGRKNAVALMEERDQKIARVKQGAGKIVSKYTKQFSKKNYLTHYKNLMKTPSLLKKFCPGNI
DEEKVNYLSKTAKTLFKHKQLELEDLAPLLYIKANLEGFSTEIESTNVIIDEAQDFSLFQLHTLKYVLNTKNFTLLGDLS
QGIHAYRSIKDWETVNNHIFDKEATSLSLQQSYRTTVEIMNLANQILEQSVNDNVPLARPVVRHGKKPENNVYTQIPDLI
QDLAETITKLQSSNYNSIAIIGKTMNECETIKQNLQQQRIDLPVLTGSEEDYQAGAVIIPSYATKGLEFDTALIVNLEEE
YQKNELDAKLLYVSMTRAMHELYIFNILGKIEFLN

Sequences:

>Translated_755_residues
MSELNHPDYNEELDHLERTKSYMDHFINEISNKQQHSAGQIKEAYEILDFLDSSQSYITILVNARYLDHSTETVDKVKRA
KSSPYFSRIDFRDHRDEEPKSYYIGKLSLFKEDNEPVIIDWRSPIASLYYEGRLGEVSYKAYEGEITGELSLKRQYTIEN
EELQDFFDVDITTTDELLQASLRGSADNKLKDIVSTIQAEQNQVIRADLNKPLIVQGTAGSGKTTIALHRIAYLIYTYEK
SFNPENFMIIAPNKLFLDYISNVLPDLGVEEAKQTTFTSFCFELLEIKEQLTLQDYKLSTLLENYGLTNSEKDLIKWRAT
FKGSMTFKKLIDNYICQIEQDLLPKEGIELEGYSIMSKDEITTAFMKDYSYLPLFQRIDHIKKKLSTRAKQQKSLIIQSI
QSEYEQKIDQARKSENQELGRKNAVALMEERDQKIARVKQGAGKIVSKYTKQFSKKNYLTHYKNLMKTPSLLKKFCPGNI
DEEKVNYLSKTAKTLFKHKQLELEDLAPLLYIKANLEGFSTEIESTNVIIDEAQDFSLFQLHTLKYVLNTKNFTLLGDLS
QGIHAYRSIKDWETVNNHIFDKEATSLSLQQSYRTTVEIMNLANQILEQSVNDNVPLARPVVRHGKKPENNVYTQIPDLI
QDLAETITKLQSSNYNSIAIIGKTMNECETIKQNLQQQRIDLPVLTGSEEDYQAGAVIIPSYATKGLEFDTALIVNLEEE
YQKNELDAKLLYVSMTRAMHELYIFNILGKIEFLN
>Mature_754_residues
SELNHPDYNEELDHLERTKSYMDHFINEISNKQQHSAGQIKEAYEILDFLDSSQSYITILVNARYLDHSTETVDKVKRAK
SSPYFSRIDFRDHRDEEPKSYYIGKLSLFKEDNEPVIIDWRSPIASLYYEGRLGEVSYKAYEGEITGELSLKRQYTIENE
ELQDFFDVDITTTDELLQASLRGSADNKLKDIVSTIQAEQNQVIRADLNKPLIVQGTAGSGKTTIALHRIAYLIYTYEKS
FNPENFMIIAPNKLFLDYISNVLPDLGVEEAKQTTFTSFCFELLEIKEQLTLQDYKLSTLLENYGLTNSEKDLIKWRATF
KGSMTFKKLIDNYICQIEQDLLPKEGIELEGYSIMSKDEITTAFMKDYSYLPLFQRIDHIKKKLSTRAKQQKSLIIQSIQ
SEYEQKIDQARKSENQELGRKNAVALMEERDQKIARVKQGAGKIVSKYTKQFSKKNYLTHYKNLMKTPSLLKKFCPGNID
EEKVNYLSKTAKTLFKHKQLELEDLAPLLYIKANLEGFSTEIESTNVIIDEAQDFSLFQLHTLKYVLNTKNFTLLGDLSQ
GIHAYRSIKDWETVNNHIFDKEATSLSLQQSYRTTVEIMNLANQILEQSVNDNVPLARPVVRHGKKPENNVYTQIPDLIQ
DLAETITKLQSSNYNSIAIIGKTMNECETIKQNLQQQRIDLPVLTGSEEDYQAGAVIIPSYATKGLEFDTALIVNLEEEY
QKNELDAKLLYVSMTRAMHELYIFNILGKIEFLN

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 87120; Mature: 86989

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELNHPDYNEELDHLERTKSYMDHFINEISNKQQHSAGQIKEAYEILDFLDSSQSYITI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LVNARYLDHSTETVDKVKRAKSSPYFSRIDFRDHRDEEPKSYYIGKLSLFKEDNEPVIID
EEEEEECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEEEEECCCCCEEEE
WRSPIASLYYEGRLGEVSYKAYEGEITGELSLKRQYTIENEELQDFFDVDITTTDELLQA
CCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHH
SLRGSADNKLKDIVSTIQAEQNQVIRADLNKPLIVQGTAGSGKTTIALHRIAYLIYTYEK
HHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHC
SFNPENFMIIAPNKLFLDYISNVLPDLGVEEAKQTTFTSFCFELLEIKEQLTLQDYKLST
CCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLENYGLTNSEKDLIKWRATFKGSMTFKKLIDNYICQIEQDLLPKEGIELEGYSIMSKDE
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHHH
ITTAFMKDYSYLPLFQRIDHIKKKLSTRAKQQKSLIIQSIQSEYEQKIDQARKSENQELG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKNAVALMEERDQKIARVKQGAGKIVSKYTKQFSKKNYLTHYKNLMKTPSLLKKFCPGNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
DEEKVNYLSKTAKTLFKHKQLELEDLAPLLYIKANLEGFSTEIESTNVIIDEAQDFSLFQ
CHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCHHH
LHTLKYVLNTKNFTLLGDLSQGIHAYRSIKDWETVNNHIFDKEATSLSLQQSYRTTVEIM
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NLANQILEQSVNDNVPLARPVVRHGKKPENNVYTQIPDLIQDLAETITKLQSSNYNSIAI
HHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IGKTMNECETIKQNLQQQRIDLPVLTGSEEDYQAGAVIIPSYATKGLEFDTALIVNLEEE
EECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECCCCCCCCCCCEEEEEEEHHH
YQKNELDAKLLYVSMTRAMHELYIFNILGKIEFLN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SELNHPDYNEELDHLERTKSYMDHFINEISNKQQHSAGQIKEAYEILDFLDSSQSYITI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LVNARYLDHSTETVDKVKRAKSSPYFSRIDFRDHRDEEPKSYYIGKLSLFKEDNEPVIID
EEEEEECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEEEEECCCCCEEEE
WRSPIASLYYEGRLGEVSYKAYEGEITGELSLKRQYTIENEELQDFFDVDITTTDELLQA
CCCHHHHHHCCCCCCCEEEEEECCCEEEEEEEEEEECCCCHHHHHHHCCCCCCHHHHHHH
SLRGSADNKLKDIVSTIQAEQNQVIRADLNKPLIVQGTAGSGKTTIALHRIAYLIYTYEK
HHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHC
SFNPENFMIIAPNKLFLDYISNVLPDLGVEEAKQTTFTSFCFELLEIKEQLTLQDYKLST
CCCCCCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLENYGLTNSEKDLIKWRATFKGSMTFKKLIDNYICQIEQDLLPKEGIELEGYSIMSKDE
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCHHH
ITTAFMKDYSYLPLFQRIDHIKKKLSTRAKQQKSLIIQSIQSEYEQKIDQARKSENQELG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKNAVALMEERDQKIARVKQGAGKIVSKYTKQFSKKNYLTHYKNLMKTPSLLKKFCPGNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
DEEKVNYLSKTAKTLFKHKQLELEDLAPLLYIKANLEGFSTEIESTNVIIDEAQDFSLFQ
CHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCHHH
LHTLKYVLNTKNFTLLGDLSQGIHAYRSIKDWETVNNHIFDKEATSLSLQQSYRTTVEIM
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NLANQILEQSVNDNVPLARPVVRHGKKPENNVYTQIPDLIQDLAETITKLQSSNYNSIAI
HHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IGKTMNECETIKQNLQQQRIDLPVLTGSEEDYQAGAVIIPSYATKGLEFDTALIVNLEEE
EECCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEECCCCCCCCCCCEEEEEEEHHH
YQKNELDAKLLYVSMTRAMHELYIFNILGKIEFLN
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]