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The map label for this gene is trkA [H]

Identifier: 188585518

GI number: 188585518

Start: 937583

End: 938923

Strand: Reverse

Name: trkA [H]

Synonym: Nther_0890

Alternate gene names: 188585518

Gene position: 938923-937583 (Counterclockwise)

Preceding gene: 188585519

Following gene: 188585517

Centisome position: 29.66

GC content: 29.98

Gene sequence:

>1341_bases
ATGCTTGTAACAATAATTGGCGGAAGTCAAGTTGGTAAAAAACTAGCTAAAATGTTAATTAAAAGAAAACATAAAGTCAC
TTTAATTGAAGAAAATAAACAAACAGCTGAACAGCTTAAAAAAGAGCTAGACACTCTTATAATAAACGGTAGTGGCGCTA
ATATTGAAGATCTAAAAAAAGCTAACGTGGATAAGGCTAAGATGATTATTGCACTAACTGAAAATGATACTGTAAACATA
GTATCTTGTATGCTAGCTAAACAGCTAGGCGAGCCATTTACAATAAGTCAAGTTGCTAGTCTAGAAAATATTACAGAAAA
AGCTAGCAATAAAAAAGTACCAGAACAGTATTTAGGTATTGATTATTTAATTAGTCCTCAACAATCAGTTATAAGTGAAA
TTGTTGAATATATTCATTTTCCTCATGCATCTGATATCCATTATTTTGGTAAGGGGAAATCTTTGCTGCTAGGTATTAGG
GTAACGGAACAATCTGAAGTTATTAACAATTCATTAAAAAATATCGATTTACCGGAAGATTCTCAAATAATTGGCATTGA
AAGTAAAGATTGTAGCTTTAAATTGGCCTTTGACGATGAGAAGGTTTCCCCTGGTGATATAATTTATTTAGTTGGTTCAC
CTGATAGTATAAAAAAAGCAAATATCAAAATTACTAATAAGGAAGTAGAAAACCAACGTATCATAATTATTGGTGGCAAA
AAGATGGGATATAATTTAGTAAGAGAATTAGAAGAGCATTCTAAACATCATGATTTTATGATTAAGGTAATTGAAAGAGA
ACATAAACAATGCGAAGTTTTAAAAAGAAATTTACATGAAAGTATCGTATTAGAAAGCAATTACTTTAATCAAGAAGAAA
TTCTTGAAGCCAACATTGTAATCACAGTCACTGGAGATGATAAAACAAACATTATCAATTCAACTATTGCAAATCAAAAT
GGGATAGATACTATTTCAGAAATTACAAATATTCAATATGAACCGATTTATAAAGCAGTCGGAATAGAAAGTACAGTAAA
TCCCTCTTTAACTACTGCATCTCAAATTATGAAGTTTTTACGTGATATGGATATTGAAACAATGTCTATTTTTCAAAATG
GAGAAGCCGTGGGAACGGAGATTGTATTATCTGAAGATTCATCAGTAATAAACAAACAGGTTTCGGATCTCAAATTGCCT
TCAAAAATTAAAATTGGAGCTGTTATTAGAGAAGAAGATATGTTCATTCCAAATGAGAATTCAGTTTTAAAGGAAGATGA
TAGACTTGTTATTTTTACACCTCTGAATGATCAAAATTCAGTAAAGAAGTACTTAGAATGA

Upstream 100 bases:

>100_bases
TCATAACAGCACTTATAGGATTAGTATTTTTTTATAAAGCAACAGAGCTTTCAGATTACTTTTACCGAATAACAACTAAG
TGAAAATTGAGGTGTTTACA

Downstream 100 bases:

>100_bases
TATCAGTCCCGCCATAAAAGTCTTGATTATTATTGTAAAAAACTGTATAATAAGTACATCACTTGTTGTGTGTTATCAAA
GGAGGAGAATTGATGAAAAT

Product: TrkA-C domain protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MLVTIIGGSQVGKKLAKMLIKRKHKVTLIEENKQTAEQLKKELDTLIINGSGANIEDLKKANVDKAKMIIALTENDTVNI
VSCMLAKQLGEPFTISQVASLENITEKASNKKVPEQYLGIDYLISPQQSVISEIVEYIHFPHASDIHYFGKGKSLLLGIR
VTEQSEVINNSLKNIDLPEDSQIIGIESKDCSFKLAFDDEKVSPGDIIYLVGSPDSIKKANIKITNKEVENQRIIIIGGK
KMGYNLVRELEEHSKHHDFMIKVIEREHKQCEVLKRNLHESIVLESNYFNQEEILEANIVITVTGDDKTNIINSTIANQN
GIDTISEITNIQYEPIYKAVGIESTVNPSLTTASQIMKFLRDMDIETMSIFQNGEAVGTEIVLSEDSSVINKQVSDLKLP
SKIKIGAVIREEDMFIPNENSVLKEDDRLVIFTPLNDQNSVKKYLE

Sequences:

>Translated_446_residues
MLVTIIGGSQVGKKLAKMLIKRKHKVTLIEENKQTAEQLKKELDTLIINGSGANIEDLKKANVDKAKMIIALTENDTVNI
VSCMLAKQLGEPFTISQVASLENITEKASNKKVPEQYLGIDYLISPQQSVISEIVEYIHFPHASDIHYFGKGKSLLLGIR
VTEQSEVINNSLKNIDLPEDSQIIGIESKDCSFKLAFDDEKVSPGDIIYLVGSPDSIKKANIKITNKEVENQRIIIIGGK
KMGYNLVRELEEHSKHHDFMIKVIEREHKQCEVLKRNLHESIVLESNYFNQEEILEANIVITVTGDDKTNIINSTIANQN
GIDTISEITNIQYEPIYKAVGIESTVNPSLTTASQIMKFLRDMDIETMSIFQNGEAVGTEIVLSEDSSVINKQVSDLKLP
SKIKIGAVIREEDMFIPNENSVLKEDDRLVIFTPLNDQNSVKKYLE
>Mature_446_residues
MLVTIIGGSQVGKKLAKMLIKRKHKVTLIEENKQTAEQLKKELDTLIINGSGANIEDLKKANVDKAKMIIALTENDTVNI
VSCMLAKQLGEPFTISQVASLENITEKASNKKVPEQYLGIDYLISPQQSVISEIVEYIHFPHASDIHYFGKGKSLLLGIR
VTEQSEVINNSLKNIDLPEDSQIIGIESKDCSFKLAFDDEKVSPGDIIYLVGSPDSIKKANIKITNKEVENQRIIIIGGK
KMGYNLVRELEEHSKHHDFMIKVIEREHKQCEVLKRNLHESIVLESNYFNQEEILEANIVITVTGDDKTNIINSTIANQN
GIDTISEITNIQYEPIYKAVGIESTVNPSLTTASQIMKFLRDMDIETMSIFQNGEAVGTEIVLSEDSSVINKQVSDLKLP
SKIKIGAVIREEDMFIPNENSVLKEDDRLVIFTPLNDQNSVKKYLE

Specific function: Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=445, Percent_Identity=27.4157303370787, Blast_Score=176, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49996; Mature: 49996

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTIIGGSQVGKKLAKMLIKRKHKVTLIEENKQTAEQLKKELDTLIINGSGANIEDLKK
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCEEEEECCCCCHHHHHH
ANVDKAKMIIALTENDTVNIVSCMLAKQLGEPFTISQVASLENITEKASNKKVPEQYLGI
CCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCC
DYLISPQQSVISEIVEYIHFPHASDIHYFGKGKSLLLGIRVTEQSEVINNSLKNIDLPED
EEEECCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCHHHHHHHHHHCCCCCCC
SQIIGIESKDCSFKLAFDDEKVSPGDIIYLVGSPDSIKKANIKITNKEVENQRIIIIGGK
CCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCC
KMGYNLVRELEEHSKHHDFMIKVIEREHKQCEVLKRNLHESIVLESNYFNQEEILEANIV
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHEEEEEE
ITVTGDDKTNIINSTIANQNGIDTISEITNIQYEPIYKAVGIESTVNPSLTTASQIMKFL
EEEECCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHH
RDMDIETMSIFQNGEAVGTEIVLSEDSSVINKQVSDLKLPSKIKIGAVIREEDMFIPNEN
HHCCCCEEHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCEECCCCC
SVLKEDDRLVIFTPLNDQNSVKKYLE
CCEECCCCEEEEECCCCCHHHHHHCC
>Mature Secondary Structure
MLVTIIGGSQVGKKLAKMLIKRKHKVTLIEENKQTAEQLKKELDTLIINGSGANIEDLKK
CEEEEECCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCEEEEECCCCCHHHHHH
ANVDKAKMIIALTENDTVNIVSCMLAKQLGEPFTISQVASLENITEKASNKKVPEQYLGI
CCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCC
DYLISPQQSVISEIVEYIHFPHASDIHYFGKGKSLLLGIRVTEQSEVINNSLKNIDLPED
EEEECCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEECCHHHHHHHHHHCCCCCCC
SQIIGIESKDCSFKLAFDDEKVSPGDIIYLVGSPDSIKKANIKITNKEVENQRIIIIGGK
CCEEEEECCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCC
KMGYNLVRELEEHSKHHDFMIKVIEREHKQCEVLKRNLHESIVLESNYFNQEEILEANIV
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHEEEEEE
ITVTGDDKTNIINSTIANQNGIDTISEITNIQYEPIYKAVGIESTVNPSLTTASQIMKFL
EEEECCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHH
RDMDIETMSIFQNGEAVGTEIVLSEDSSVINKQVSDLKLPSKIKIGAVIREEDMFIPNEN
HHCCCCEEHHHCCCCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCEECCCCC
SVLKEDDRLVIFTPLNDQNSVKKYLE
CCEECCCCEEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]