Click here to switch to the map view.

The map label for this gene is aegA [C]

Identifier: 188585512

GI number: 188585512

Start: 930878

End: 932401

Strand: Direct

Name: aegA [C]

Synonym: Nther_0884

Alternate gene names: 188585512

Gene position: 930878-932401 (Clockwise)

Preceding gene: 188585511

Following gene: 188585513

Centisome position: 29.41

GC content: 36.22

Gene sequence:

>1524_bases
ATGAGAAAATTTGAAACCGAAGTCCAAAAAATCAATCATGAAATTATGAGAGAATTGGCTAAATTAGTTTTCAAAAATAA
ATTATTAGATGAAATAAATGAATTACCTCAAAAAATAATCCAGGGTGATGAAGCTCGGTACCGTTGTTGTGTTTACAAAG
AAAGAGCGATTATTACCGAGAGGGTACGCCTGGATATGGGTGTTAATCCAAACAATATTCACTCTAATACATTTTTAAAG
GATGATTACGAACAAGCATGCCATCGACTGGACAAGCCAGTAGTACAAGCATTAGAAAAAGCATGCGACAAATGTCCTAT
AAATAGGTTTACAGTTACTGAAGCTTGCCGGGGTTGTGTTGCTCATTATTGTATGGAAAGTTGTCCTAAAGATGCTATTA
GTTTCATTAATCGCCAGGCTTATATCAATCAAGAAAAATGTATAGAGTGTGGAAAATGTAAGAATATGTGTCCTTTTAAT
GCAATCTCTGATGTAATGCGCCCTTGTCGAAGCGCATGTACTGTAGATGCCGTTAAAGTTGATGGTGATAGAAGAATTAG
CATAGATCAAGATAAATGTGTCAGTTGTGGTGCTTGTATTGAAGCATGTCCCTTTGGTGCTATTGCCTCTAAATCCAATT
TTATTTCTTTTCTAGAGGATCTGACAGGAGGAGAGCAGATACATGCAATGATAGCACCATCTATAGCTGGTCAATTTGGA
GCCAAAGTAAAAGTTTCCCAAATAAAAGCAGCTCTTAAAAATTTAGGTATGGATTCTGTACAAGAGGTTGCTAAAGGTGC
AGATGTCGTAGCATATCATGAAGCTAAGGAATTAATATCTAGCATCCATGAGCATAATTTTATGTTAAGTTCATGTTGTC
CTGCTTTTGTCAGTTTAGTAAAGAATTTTTATTCAGAGTTTACAGCTAATTTATCTCAAACAGTCTCTCCTATGATTGCC
ATGGGTAGATCGATTAAACAAAAATATCCAGGTTCGAAAGTAGTTTTCATTGGCCCCTGTATTGCAAAGAAAGACGAAGC
CCTTGAAGAAGATGTGCAGGATGGAGTTGACTATGTGTTAACTTATGAAGAAATATGTGCTTTATTTGAAGGTGCAGGGG
TTGACCCGTCACAATGTGAGGAATTTACAGAAGAAGAGGATCAAAACAAGCTTGTCAGTCCTTTTGGAAGATGTTTTGCT
AAGAGTGGCGGAGTAGGAGAGGCAATTAAGAGAACTGTTAAAGAAATAGAACCTGATTATGATATTGATATCAATGTAGT
TAAATGCAGTGGTCTAAATGAATGTAAACAAGTTTTAGAGAAACTTAAAAATGGCAAATTAGAGGCGGATTTTATCGAAG
GAATGGGATGCGAAGAGGGATGTATCGGTGGTCCAGGCAATTTAGTAAAACCTAATAAATCTAAAGTAATGGTTGAAAAA
TACGGAAAAGAAGCAGAAATAGAAAGTGCAGTAGAGTCGGCTTCTTCCCAAATTGAAGAACCACAATTGTTTAGAGAGCA
TTAA

Upstream 100 bases:

>100_bases
TTACACAAGGCCGATAATATAAACAATTGTTGTGAAACTAATAACAATTTGTTATGATATCATTATCATTAAAGCAAATA
AATATATAGGAGGGACAACA

Downstream 100 bases:

>100_bases
TTAAAAAAGTCATAAGAAAGTAAAGTTAAGGATATAACTTTAAATTGAAAAATCGATTGAGATTAAGGCTGTAATCTAAG
TTATTTAAACACTTAGTATT

Product: hydrogenase large subunit domain protein

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MRKFETEVQKINHEIMRELAKLVFKNKLLDEINELPQKIIQGDEARYRCCVYKERAIITERVRLDMGVNPNNIHSNTFLK
DDYEQACHRLDKPVVQALEKACDKCPINRFTVTEACRGCVAHYCMESCPKDAISFINRQAYINQEKCIECGKCKNMCPFN
AISDVMRPCRSACTVDAVKVDGDRRISIDQDKCVSCGACIEACPFGAIASKSNFISFLEDLTGGEQIHAMIAPSIAGQFG
AKVKVSQIKAALKNLGMDSVQEVAKGADVVAYHEAKELISSIHEHNFMLSSCCPAFVSLVKNFYSEFTANLSQTVSPMIA
MGRSIKQKYPGSKVVFIGPCIAKKDEALEEDVQDGVDYVLTYEEICALFEGAGVDPSQCEEFTEEEDQNKLVSPFGRCFA
KSGGVGEAIKRTVKEIEPDYDIDINVVKCSGLNECKQVLEKLKNGKLEADFIEGMGCEEGCIGGPGNLVKPNKSKVMVEK
YGKEAEIESAVESASSQIEEPQLFREH

Sequences:

>Translated_507_residues
MRKFETEVQKINHEIMRELAKLVFKNKLLDEINELPQKIIQGDEARYRCCVYKERAIITERVRLDMGVNPNNIHSNTFLK
DDYEQACHRLDKPVVQALEKACDKCPINRFTVTEACRGCVAHYCMESCPKDAISFINRQAYINQEKCIECGKCKNMCPFN
AISDVMRPCRSACTVDAVKVDGDRRISIDQDKCVSCGACIEACPFGAIASKSNFISFLEDLTGGEQIHAMIAPSIAGQFG
AKVKVSQIKAALKNLGMDSVQEVAKGADVVAYHEAKELISSIHEHNFMLSSCCPAFVSLVKNFYSEFTANLSQTVSPMIA
MGRSIKQKYPGSKVVFIGPCIAKKDEALEEDVQDGVDYVLTYEEICALFEGAGVDPSQCEEFTEEEDQNKLVSPFGRCFA
KSGGVGEAIKRTVKEIEPDYDIDINVVKCSGLNECKQVLEKLKNGKLEADFIEGMGCEEGCIGGPGNLVKPNKSKVMVEK
YGKEAEIESAVESASSQIEEPQLFREH
>Mature_507_residues
MRKFETEVQKINHEIMRELAKLVFKNKLLDEINELPQKIIQGDEARYRCCVYKERAIITERVRLDMGVNPNNIHSNTFLK
DDYEQACHRLDKPVVQALEKACDKCPINRFTVTEACRGCVAHYCMESCPKDAISFINRQAYINQEKCIECGKCKNMCPFN
AISDVMRPCRSACTVDAVKVDGDRRISIDQDKCVSCGACIEACPFGAIASKSNFISFLEDLTGGEQIHAMIAPSIAGQFG
AKVKVSQIKAALKNLGMDSVQEVAKGADVVAYHEAKELISSIHEHNFMLSSCCPAFVSLVKNFYSEFTANLSQTVSPMIA
MGRSIKQKYPGSKVVFIGPCIAKKDEALEEDVQDGVDYVLTYEEICALFEGAGVDPSQCEEFTEEEDQNKLVSPFGRCFA
KSGGVGEAIKRTVKEIEPDYDIDINVVKCSGLNECKQVLEKLKNGKLEADFIEGMGCEEGCIGGPGNLVKPNKSKVMVEK
YGKEAEIESAVESASSQIEEPQLFREH

Specific function: Unknown

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 56220; Mature: 56220

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFETEVQKINHEIMRELAKLVFKNKLLDEINELPQKIIQGDEARYRCCVYKERAIITE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RVRLDMGVNPNNIHSNTFLKDDYEQACHRLDKPVVQALEKACDKCPINRFTVTEACRGCV
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AHYCMESCPKDAISFINRQAYINQEKCIECGKCKNMCPFNAISDVMRPCRSACTVDAVKV
HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
DGDRRISIDQDKCVSCGACIEACPFGAIASKSNFISFLEDLTGGEQIHAMIAPSIAGQFG
CCCCEECCCHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKVKVSQIKAALKNLGMDSVQEVAKGADVVAYHEAKELISSIHEHNFMLSSCCPAFVSLV
CCCHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KNFYSEFTANLSQTVSPMIAMGRSIKQKYPGSKVVFIGPCIAKKDEALEEDVQDGVDYVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHH
TYEEICALFEGAGVDPSQCEEFTEEEDQNKLVSPFGRCFAKSGGVGEAIKRTVKEIEPDY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
DIDINVVKCSGLNECKQVLEKLKNGKLEADFIEGMGCEEGCIGGPGNLVKPNKSKVMVEK
CCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
YGKEAEIESAVESASSQIEEPQLFREH
CCCHHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MRKFETEVQKINHEIMRELAKLVFKNKLLDEINELPQKIIQGDEARYRCCVYKERAIITE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
RVRLDMGVNPNNIHSNTFLKDDYEQACHRLDKPVVQALEKACDKCPINRFTVTEACRGCV
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AHYCMESCPKDAISFINRQAYINQEKCIECGKCKNMCPFNAISDVMRPCRSACTVDAVKV
HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEE
DGDRRISIDQDKCVSCGACIEACPFGAIASKSNFISFLEDLTGGEQIHAMIAPSIAGQFG
CCCCEECCCHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
AKVKVSQIKAALKNLGMDSVQEVAKGADVVAYHEAKELISSIHEHNFMLSSCCPAFVSLV
CCCHHHHHHHHHHHCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
KNFYSEFTANLSQTVSPMIAMGRSIKQKYPGSKVVFIGPCIAKKDEALEEDVQDGVDYVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHH
TYEEICALFEGAGVDPSQCEEFTEEEDQNKLVSPFGRCFAKSGGVGEAIKRTVKEIEPDY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
DIDINVVKCSGLNECKQVLEKLKNGKLEADFIEGMGCEEGCIGGPGNLVKPNKSKVMVEK
CCEEEEEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
YGKEAEIESAVESASSQIEEPQLFREH
CCCHHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]