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The map label for this gene is mcrC [C]

Identifier: 188585435

GI number: 188585435

Start: 840455

End: 841606

Strand: Direct

Name: mcrC [C]

Synonym: Nther_0806

Alternate gene names: 188585435

Gene position: 840455-841606 (Clockwise)

Preceding gene: 188585434

Following gene: 188585436

Centisome position: 26.55

GC content: 28.99

Gene sequence:

>1152_bases
ATGATGGATAATACTCTAAAGCTAAAAGAGTATGATGAAAGTAATAAACTTCAATTAAGACAGGACCATCTGGATTTATT
ACTAGCTAAATTTGATAATCAACTAAAGGTCAAGTCAGCTATTGATAGATCAGGATATATTATATGTAGTAACAGTTATG
TGGGAGTTTACGATTTAGATGACTTTAAAATCGTAGTAGAGCCTAAAATTGATACAGCCAATGTGTTTAAAATGCTTTCC
TACTCTTATGATTTAATTTTTTGGCATGATGAAAAAGCACAATTCGCTAATATTCAGGAACTACTAGATTATTTAGTGTT
GGTATTTTGTAATCAGGTTAATAGGCTTATCAAAAAAGGACTACATGCTGATTATGTACTTGTTAATGATAAATTAAGCT
ATGCTAAAGGGCGCATGAATGTTAGAGAATTGGTAGAAAAGCCTTGGGAAAAGCATAAAATTGATTGTTATTATGACAAT
TATCAAGTTGATATTTTAGAGAATCAAATTATAAAGTTTACAATTGATTTGTTAAAAAGGTATATCCAAAATAATTGGAT
AAGAAGATCACTGTTAAATACAAACAGATACTTTGATTCTGTTTCCTTAAGGCCTATTACAGTAGAAGATATTGATCAAG
TTCAGTACACCACATTAAATAAACATTACAAACACATTCATAACTTCTGTAAAATGTTTTTAGAGTTAATGGGTATAAAT
GAACAAATTGGAGAAACTCTTTTTAATCAGTTTCACTTAGAAATGAACAACCTATATGAAAAATATGTAGGGAAATTATT
AAAGGAAGAGTTACCAAATAATTATTGTGTTATTCTCCAGGATAAGCTTCACTTAGATGAATATGATCAGATAAGCATTA
GGCCGGATATTGTAATTTATAATGATGTAAAGCCTTATTTAGTTATTGATACCAAGTATAAGGGTTCCAAAGATATTACG
AATAATGACATTTACCAAATGGCAGCTTATATGAGTAAAACAAAAACAGATGGTGTATTATTGTATCCTGCTCAAGAAGT
GGCTGAAACAGAATATATTATAAATGGTAGGAGCCTCAATATAAAAACTATTGACTTACAAAACCTTGATGATGGTGCAA
AGGATTTAATAAACTGGATAATTAAAGTTTGA

Upstream 100 bases:

>100_bases
TTTATCCTTATTTAGAAGAGTACTTCATTGATGATATGAATTCAAATATTGATAAATTCAAATGGGAAAATGTCAAGCAT
AGATTAAAGGAATTGATAGA

Downstream 100 bases:

>100_bases
TATTTTGTGGAGGGGTGTATTATGGTGGAAGATGGTGAAAAGATCTCTGGGCATCCTATATTAATAAAAAGCGATGAAAA
TATATCTGATATTGAAAAAA

Product: McrBC 5-methylcytosine restriction system component-like protein

Products: NA

Alternate protein names: McrBC 5-Methylcytosine Restriction System Component; Restriction Modulator Protein; McrBC 5-Methylcytosine Restriction System Component-Like; 5-Methylcytosine-Specific Restriction Subunit McrC; 5-Methylcytosine Restriction System Component- Like Protein; McrBC Catalytic Subunit McrC; McrBC 5-Methylcytosine Restriction Subunit McrC; McrBC Restriction Endonuclease System Subunit McrC; 5-Methylcytosine-Specific Restriction Subunit Mcr; 5-Methylcytosine Restriction System Component; McrBC Restriction Endonuclease System Protein McrC; 5-Methylcytosine Restriction System Catalytic Subunit

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MMDNTLKLKEYDESNKLQLRQDHLDLLLAKFDNQLKVKSAIDRSGYIICSNSYVGVYDLDDFKIVVEPKIDTANVFKMLS
YSYDLIFWHDEKAQFANIQELLDYLVLVFCNQVNRLIKKGLHADYVLVNDKLSYAKGRMNVRELVEKPWEKHKIDCYYDN
YQVDILENQIIKFTIDLLKRYIQNNWIRRSLLNTNRYFDSVSLRPITVEDIDQVQYTTLNKHYKHIHNFCKMFLELMGIN
EQIGETLFNQFHLEMNNLYEKYVGKLLKEELPNNYCVILQDKLHLDEYDQISIRPDIVIYNDVKPYLVIDTKYKGSKDIT
NNDIYQMAAYMSKTKTDGVLLYPAQEVAETEYIINGRSLNIKTIDLQNLDDGAKDLINWIIKV

Sequences:

>Translated_383_residues
MMDNTLKLKEYDESNKLQLRQDHLDLLLAKFDNQLKVKSAIDRSGYIICSNSYVGVYDLDDFKIVVEPKIDTANVFKMLS
YSYDLIFWHDEKAQFANIQELLDYLVLVFCNQVNRLIKKGLHADYVLVNDKLSYAKGRMNVRELVEKPWEKHKIDCYYDN
YQVDILENQIIKFTIDLLKRYIQNNWIRRSLLNTNRYFDSVSLRPITVEDIDQVQYTTLNKHYKHIHNFCKMFLELMGIN
EQIGETLFNQFHLEMNNLYEKYVGKLLKEELPNNYCVILQDKLHLDEYDQISIRPDIVIYNDVKPYLVIDTKYKGSKDIT
NNDIYQMAAYMSKTKTDGVLLYPAQEVAETEYIINGRSLNIKTIDLQNLDDGAKDLINWIIKV
>Mature_383_residues
MMDNTLKLKEYDESNKLQLRQDHLDLLLAKFDNQLKVKSAIDRSGYIICSNSYVGVYDLDDFKIVVEPKIDTANVFKMLS
YSYDLIFWHDEKAQFANIQELLDYLVLVFCNQVNRLIKKGLHADYVLVNDKLSYAKGRMNVRELVEKPWEKHKIDCYYDN
YQVDILENQIIKFTIDLLKRYIQNNWIRRSLLNTNRYFDSVSLRPITVEDIDQVQYTTLNKHYKHIHNFCKMFLELMGIN
EQIGETLFNQFHLEMNNLYEKYVGKLLKEELPNNYCVILQDKLHLDEYDQISIRPDIVIYNDVKPYLVIDTKYKGSKDIT
NNDIYQMAAYMSKTKTDGVLLYPAQEVAETEYIINGRSLNIKTIDLQNLDDGAKDLINWIIKV

Specific function: Modifies The Specificity Of Mcrb Restriction By Expanding The Range Of Modified Sequences Restricted. Does Not Bind To DNA. [C]

COG id: COG4268

COG function: function code V; McrBC 5-methylcytosine restriction system component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790804, Length=330, Percent_Identity=23.9393939393939, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45336; Mature: 45336

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDNTLKLKEYDESNKLQLRQDHLDLLLAKFDNQLKVKSAIDRSGYIICSNSYVGVYDLD
CCCCCEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEHHHHHCCCCEEEECCCEEEEEECC
DFKIVVEPKIDTANVFKMLSYSYDLIFWHDEKAQFANIQELLDYLVLVFCNQVNRLIKKG
CEEEEEECCCCHHHHHHHHHCCEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCC
LHADYVLVNDKLSYAKGRMNVRELVEKPWEKHKIDCYYDNYQVDILENQIIKFTIDLLKR
CCCCEEEEECCHHHHHCCCCHHHHHHCCHHHCCEEEEECCEEEEEEHHHHHHHHHHHHHH
YIQNNWIRRSLLNTNRYFDSVSLRPITVEDIDQVQYTTLNKHYKHIHNFCKMFLELMGIN
HHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQIGETLFNQFHLEMNNLYEKYVGKLLKEELPNNYCVILQDKLHLDEYDQISIRPDIVIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCEEEE
NDVKPYLVIDTKYKGSKDITNNDIYQMAAYMSKTKTDGVLLYPAQEVAETEYIINGRSLN
ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHCCCEEEEECCEEE
IKTIDLQNLDDGAKDLINWIIKV
EEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MMDNTLKLKEYDESNKLQLRQDHLDLLLAKFDNQLKVKSAIDRSGYIICSNSYVGVYDLD
CCCCCEEEEECCCCCCEEEHHHHHHHHHHHHCCCEEHHHHHCCCCEEEECCCEEEEEECC
DFKIVVEPKIDTANVFKMLSYSYDLIFWHDEKAQFANIQELLDYLVLVFCNQVNRLIKKG
CEEEEEECCCCHHHHHHHHHCCEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCC
LHADYVLVNDKLSYAKGRMNVRELVEKPWEKHKIDCYYDNYQVDILENQIIKFTIDLLKR
CCCCEEEEECCHHHHHCCCCHHHHHHCCHHHCCEEEEECCEEEEEEHHHHHHHHHHHHHH
YIQNNWIRRSLLNTNRYFDSVSLRPITVEDIDQVQYTTLNKHYKHIHNFCKMFLELMGIN
HHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQIGETLFNQFHLEMNNLYEKYVGKLLKEELPNNYCVILQDKLHLDEYDQISIRPDIVIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCEEEE
NDVKPYLVIDTKYKGSKDITNNDIYQMAAYMSKTKTDGVLLYPAQEVAETEYIINGRSLN
ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHCCCEEEEECCEEE
IKTIDLQNLDDGAKDLINWIIKV
EEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA