BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is yhdH [H]

Identifier: 188585333

GI number: 188585333

Start: 724426

End: 725772

Strand: Direct

Name: yhdH [H]

Synonym: Nther_0698

Alternate gene names: 188585333

Gene position: 724426-725772 (Clockwise)

Preceding gene: 188585332

Following gene: 188585334

Centisome position: 22.88

GC content: 39.5

Gene sequence:

>1347_bases
ATGCCTGATCAACGTGAACAATGGAAGTCGAAATTAGGTTTCGTACTTGCGGCGGCAGGCTCAGCTGTAGGCTTAGGTAA
TGTCTGGAGATTTCCCTTTGTAACAGGGGAAGAAGGTGGAGCTGCCTTTTTAATTATTTACATTATCGCAATAATAATTA
TAGGCTATCCCCTTATGGTAACTGAAATTTCTTTGGGTAGACATACTCAAAGAAATCCGGTTGGTGCTTTTAAATCAATT
GCTCCTAATACTCCTTGGTGGCTTGTTGGTGCTTTATCTGTGCTAACAGGGTTTGTCATCCTAAGTTATTATTCTGTTAT
TGCTGGTTGGTCTCTATCTTACATTGTTAAATCTTTAGCAGGTTTTCCAATAGGAATAGAAGCCACAGAGCAGCTATTTG
GTGAACACACTACAAGTCTTTTTGAACCAATTTTTTATCACTTTTTATTCATGGCGATTGTAGTCGGTGTTATATCAGCT
GGAGTTGTGAAAGGTATTCAAAGAGTGGTCACTTTTCTCATGCCAGTGTTGGTAGTACTATTACTGGCTGTTGTTATTAG
GGCTGTCACTTTACCCGGAGCTGGAGAGGGTTTAGCATTCCTATTTAGGCCGGATTTCAGTGCGGTTAGTTGGGATACTA
TTCTCGCTGCCATAGGTCAGTCATTCTTCACTTTAAGTCTTGGTATGGGTGCTATTTTAACTTATGGAAGTTATCTTTCT
AAGAATGATGAAATACCTAACAGTTCAGTTCAGGTAATTGGTGCCGATGCTCTGATTGCAATTATTTCAGGTATGGCTAT
TTTCCCTGCTGTTTTTGCTTTAGGATTTGACCCTGGTGAAGGTCCTGGATTGGTATTCGTCACTTTACCGGCTGTTTTTG
CAGAAATGCCTGTTGGTGGACTTTTTGGATTCTTATTCTTTGTCTTATTATCCATTGCGGCATTAACCTCTGCCATTTCA
TTGCTAGAGGTAGTTGTAGCTTATTTCGTAGACGAAAAACAATGGCCTAGAAAAAAAGCTTCTGCTACTATAGGTTTGGT
TGCTTTTATCGTAGGGCTTTTCCCAGTTTTAGGTTATAGCGCCCTAGATCATGTTACCTTTATGGGCATGGATATCTTAG
ACACTTATGATTTTATAGCAGATAGTATTATGTTACCACTAGGTGGGGCTATGATTGCTTTCTTTGCCGGTCATGTTTGG
GGTACTAGAAATGTTATGGAAGAAGCAAATAAATCTGCCACCGGTATTAGGATTGGCGATTGGGCAGCACCATTATTAAA
GTATATAATCCCTATTGGCGTTATCATAGTAATGATTGTAGGAATTATAGAGACTATTGGTGGTTAA

Upstream 100 bases:

>100_bases
GGAATGATGAAAGTTTTTAGATTAAGGTTAATTAATCTCTGGTTATTAGGCTTAAACCAGGGATTGATTGAATAATAATA
ACTTAAAAAGGAGGTTTTTC

Downstream 100 bases:

>100_bases
AAATTAGATCTCTAATAATATTTAAGGGCATCCAGACTTAATGGGTGCCCTTTTATTATGTTAAAATTCAGTTATGCTTA
TTAACCAAATCTTTTTAACC

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MPDQREQWKSKLGFVLAAAGSAVGLGNVWRFPFVTGEEGGAAFLIIYIIAIIIIGYPLMVTEISLGRHTQRNPVGAFKSI
APNTPWWLVGALSVLTGFVILSYYSVIAGWSLSYIVKSLAGFPIGIEATEQLFGEHTTSLFEPIFYHFLFMAIVVGVISA
GVVKGIQRVVTFLMPVLVVLLLAVVIRAVTLPGAGEGLAFLFRPDFSAVSWDTILAAIGQSFFTLSLGMGAILTYGSYLS
KNDEIPNSSVQVIGADALIAIISGMAIFPAVFALGFDPGEGPGLVFVTLPAVFAEMPVGGLFGFLFFVLLSIAALTSAIS
LLEVVVAYFVDEKQWPRKKASATIGLVAFIVGLFPVLGYSALDHVTFMGMDILDTYDFIADSIMLPLGGAMIAFFAGHVW
GTRNVMEEANKSATGIRIGDWAAPLLKYIIPIGVIIVMIVGIIETIGG

Sequences:

>Translated_448_residues
MPDQREQWKSKLGFVLAAAGSAVGLGNVWRFPFVTGEEGGAAFLIIYIIAIIIIGYPLMVTEISLGRHTQRNPVGAFKSI
APNTPWWLVGALSVLTGFVILSYYSVIAGWSLSYIVKSLAGFPIGIEATEQLFGEHTTSLFEPIFYHFLFMAIVVGVISA
GVVKGIQRVVTFLMPVLVVLLLAVVIRAVTLPGAGEGLAFLFRPDFSAVSWDTILAAIGQSFFTLSLGMGAILTYGSYLS
KNDEIPNSSVQVIGADALIAIISGMAIFPAVFALGFDPGEGPGLVFVTLPAVFAEMPVGGLFGFLFFVLLSIAALTSAIS
LLEVVVAYFVDEKQWPRKKASATIGLVAFIVGLFPVLGYSALDHVTFMGMDILDTYDFIADSIMLPLGGAMIAFFAGHVW
GTRNVMEEANKSATGIRIGDWAAPLLKYIIPIGVIIVMIVGIIETIGG
>Mature_447_residues
PDQREQWKSKLGFVLAAAGSAVGLGNVWRFPFVTGEEGGAAFLIIYIIAIIIIGYPLMVTEISLGRHTQRNPVGAFKSIA
PNTPWWLVGALSVLTGFVILSYYSVIAGWSLSYIVKSLAGFPIGIEATEQLFGEHTTSLFEPIFYHFLFMAIVVGVISAG
VVKGIQRVVTFLMPVLVVLLLAVVIRAVTLPGAGEGLAFLFRPDFSAVSWDTILAAIGQSFFTLSLGMGAILTYGSYLSK
NDEIPNSSVQVIGADALIAIISGMAIFPAVFALGFDPGEGPGLVFVTLPAVFAEMPVGGLFGFLFFVLLSIAALTSAISL
LEVVVAYFVDEKQWPRKKASATIGLVAFIVGLFPVLGYSALDHVTFMGMDILDTYDFIADSIMLPLGGAMIAFFAGHVWG
TRNVMEEANKSATGIRIGDWAAPLLKYIIPIGVIIVMIVGIIETIGG

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=433, Percent_Identity=27.4826789838337, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI171184408, Length=435, Percent_Identity=26.8965517241379, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI171184406, Length=435, Percent_Identity=26.8965517241379, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI171184404, Length=435, Percent_Identity=26.8965517241379, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI21361581, Length=482, Percent_Identity=25.103734439834, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI4507043, Length=400, Percent_Identity=26.5, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI197276623, Length=498, Percent_Identity=26.7068273092369, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI54607094, Length=498, Percent_Identity=26.7068273092369, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI194018524, Length=297, Percent_Identity=29.96632996633, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7657587, Length=467, Percent_Identity=25.2676659528908, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI51468073, Length=443, Percent_Identity=25.2821670428894, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI289191351, Length=500, Percent_Identity=25.2, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4557046, Length=500, Percent_Identity=25.2, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI289191377, Length=500, Percent_Identity=25.2, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI4507041, Length=423, Percent_Identity=25.531914893617, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI134304856, Length=413, Percent_Identity=29.2978208232446, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI33354281, Length=297, Percent_Identity=27.6094276094276, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI58219014, Length=298, Percent_Identity=26.8456375838926, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI11181770, Length=306, Percent_Identity=28.4313725490196, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI92859670, Length=455, Percent_Identity=24.3956043956044, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI6005715, Length=436, Percent_Identity=25.2293577981651, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI21361693, Length=116, Percent_Identity=41.3793103448276, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI12408638, Length=275, Percent_Identity=29.4545454545455, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI197276625, Length=119, Percent_Identity=40.3361344537815, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI300360519, Length=284, Percent_Identity=25.3521126760563, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5032097, Length=115, Percent_Identity=35.6521739130435, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI218563756, Length=115, Percent_Identity=35.6521739130435, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI67782317, Length=79, Percent_Identity=41.7721518987342, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI55749589, Length=273, Percent_Identity=24.5421245421245, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI67782315, Length=79, Percent_Identity=41.7721518987342, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI67782313, Length=79, Percent_Identity=41.7721518987342, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI289191353, Length=317, Percent_Identity=23.3438485804416, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=482, Percent_Identity=25.3112033195021, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17554804, Length=469, Percent_Identity=26.0127931769723, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI25146584, Length=433, Percent_Identity=25.635103926097, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17569475, Length=406, Percent_Identity=27.3399014778325, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71998244, Length=331, Percent_Identity=30.2114803625378, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71995588, Length=409, Percent_Identity=26.8948655256724, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI133952791, Length=248, Percent_Identity=27.8225806451613, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI212642127, Length=255, Percent_Identity=26.2745098039216, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17542050, Length=117, Percent_Identity=34.1880341880342, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=124, Percent_Identity=33.0645161290323, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136952, Length=375, Percent_Identity=29.8666666666667, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281364394, Length=375, Percent_Identity=29.8666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28574704, Length=375, Percent_Identity=29.8666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17136950, Length=375, Percent_Identity=29.8666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28574702, Length=375, Percent_Identity=29.8666666666667, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24762620, Length=418, Percent_Identity=27.7511961722488, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24652942, Length=403, Percent_Identity=26.7990074441687, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45551088, Length=403, Percent_Identity=26.7990074441687, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI45550877, Length=443, Percent_Identity=25.7336343115124, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45551183, Length=456, Percent_Identity=26.3157894736842, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281363702, Length=376, Percent_Identity=29.5212765957447, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24661428, Length=505, Percent_Identity=24.7524752475248, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24582567, Length=451, Percent_Identity=26.3858093126386, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639514, Length=522, Percent_Identity=22.9885057471264, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221329674, Length=521, Percent_Identity=23.2245681381958, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281365034, Length=479, Percent_Identity=25.0521920668058, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI19921936, Length=390, Percent_Identity=26.6666666666667, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281363700, Length=338, Percent_Identity=30.4733727810651, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281364136, Length=403, Percent_Identity=26.0545905707196, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24639853, Length=519, Percent_Identity=26.5895953757225, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24655079, Length=296, Percent_Identity=29.0540540540541, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24639516, Length=539, Percent_Identity=22.4489795918367, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24654186, Length=309, Percent_Identity=28.1553398058252, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24582569, Length=417, Percent_Identity=23.5011990407674, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921352, Length=287, Percent_Identity=26.1324041811847, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584353, Length=287, Percent_Identity=26.1324041811847, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 47792; Mature: 47661

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDQREQWKSKLGFVLAAAGSAVGLGNVWRFPFVTGEEGGAAFLIIYIIAIIIIGYPLMV
CCHHHHHHHHHCCHHEECCCCCCCCCCEECCEEECCCCCHHHHHHHHHHHHHHCCHHHH
TEISLGRHTQRNPVGAFKSIAPNTPWWLVGALSVLTGFVILSYYSVIAGWSLSYIVKSLA
HEEHHCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GFPIGIEATEQLFGEHTTSLFEPIFYHFLFMAIVVGVISAGVVKGIQRVVTFLMPVLVVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAVVIRAVTLPGAGEGLAFLFRPDFSAVSWDTILAAIGQSFFTLSLGMGAILTYGSYLS
HHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNDEIPNSSVQVIGADALIAIISGMAIFPAVFALGFDPGEGPGLVFVTLPAVFAEMPVGG
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHCCHHH
LFGFLFFVLLSIAALTSAISLLEVVVAYFVDEKQWPRKKASATIGLVAFIVGLFPVLGYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALDHVTFMGMDILDTYDFIADSIMLPLGGAMIAFFAGHVWGTRNVMEEANKSATGIRIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCEECH
WAAPLLKYIIPIGVIIVMIVGIIETIGG
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]