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The map label for this gene is nreB [H]

Identifier: 188585287

GI number: 188585287

Start: 672416

End: 673888

Strand: Reverse

Name: nreB [H]

Synonym: Nther_0649

Alternate gene names: 188585287

Gene position: 673888-672416 (Counterclockwise)

Preceding gene: 188585288

Following gene: 188585286

Centisome position: 21.29

GC content: 34.01

Gene sequence:

>1473_bases
ATGATAAATAAAATTAAAAATAAAATTGGTATTAAAGAGAAAATAATAGCTATTGTAGTTATAATTGTATTAATGCTTGG
GATTTGGACTGTAGTTCAAGTCAGGTCAACTACCTCAAGTGCATTAAACGAGTACTTGCAACGCCATGGAATTTCCATAG
CTAAAAATGTTAGCACTAGAAGTGAAAATTATTTATTAACTAACGACCGTTATAGATTACATCAACTGGTATCCGAAACT
ATGGATAATAATTCAGATGTTGAATATTTATTTATAGAAGGGGCGGGAGGAACTGTAGAAATCAGTTCTTTTGCCAATGA
ATTACCAGACAATTTGAAGCAAGTAAATACTGTTGAGGAAAATGAGGAATATAATATTCAACCTTTAAATACTGAACATG
GACTAGTCTATGACATTGCAGTACCAATATTTGAGGGTAGAATTGGTACTGTTCGCCTGGGAATGTCTACTAGTGAAATC
GATCAGTTAGTTCATCAAATTTGTAGCAATATTTGGTTAACAGTTTTGATAGTTTCTATAGTTGGTTTGATTACAGCTTA
TTTATTATCTCTTATAATAATCAATCCAATATATCGACTAGTTTCAGCCACTGAACAAGTAGCAAAGGGTCATTTACATG
GTATCCCCCTGGTGGTAACAAATGATGAAATTGGCAAGCTATCCCTATCTTTTAAGAAAATGATTGAAGGACTTAAATCT
TTACGAGAAAATAATGAGAGTTGTTGGGTCCAACTTGAAAAAAAAGAAGAGATGAGAAAAAAATTGTTAAACAAAATGAT
GTCCGCCCAGGAAGAAGAGCGGAAAAAAATATCAAGGGAGCTTCATGATGGAACCGGACAATCTTTGACTACTTTAAAGT
TAGCGTTAAAACAAATCAGCGAAACAAACGATTTAGAAGAAGCTAAAAGAATGTCTGAAGAACTAAGAGAACTTACTGGA
GATGTAATTGATGAAATCAAAAGTTTGGCCAGGGATCTGCGTCCTAGTGTGTTAGATGATTTGGGATTAGACTATGCCCT
AGAAAAATATCTCAAAGAAATACAAGGAAGGACTGGAGTATCTACCGAATTTTGGTTTCAAGCAGATCAAGGATTAAAAT
TAGAGCCAGAAATTTCTACTAATATTTATCGGATAGTCCAAGAATCTGTCAATAACTCTATCAAACACGCTGATGCTAGT
AAAATTGATGTGATTGTCAAGACCATTTCTTCTCAGTTAATAGTTATTATTGAAGATGATGGGAAAGGATTTGACCTGGA
ACAGTTTTCTGATAATTATAAACAAAATGAAACGCGGGGACTTGGAATATTTGGAATGGAAGAAAGAGCAGAATTAATTG
GGGGACATTTGGCGATTGAAAGCACTCCCGGAGATGGTACTGCCGTTTATTTAAAGATTAATTTAGCAAAGGAGGAAACA
TCAAACCATGACTATTTCGGTACTAGTAGTTGA

Upstream 100 bases:

>100_bases
AATGGTCAATATATATTGGAGCAATTGGGAATTGAGCAGTTTGAGCCCGCTCAAGATAGTAGCTATGACTCCATCAGAGA
TATGGCCGAGGTGGTAGGTT

Downstream 100 bases:

>100_bases
TGATCATGCCGTACTTGGAAAAGGATTGAGTATGCTTTTAAATTCCCAAGATGATATGGAGGTATGTGGGCAAGTTGGTA
CTGCCAAAGAAGCTTTAGAT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MINKIKNKIGIKEKIIAIVVIIVLMLGIWTVVQVRSTTSSALNEYLQRHGISIAKNVSTRSENYLLTNDRYRLHQLVSET
MDNNSDVEYLFIEGAGGTVEISSFANELPDNLKQVNTVEENEEYNIQPLNTEHGLVYDIAVPIFEGRIGTVRLGMSTSEI
DQLVHQICSNIWLTVLIVSIVGLITAYLLSLIIINPIYRLVSATEQVAKGHLHGIPLVVTNDEIGKLSLSFKKMIEGLKS
LRENNESCWVQLEKKEEMRKKLLNKMMSAQEEERKKISRELHDGTGQSLTTLKLALKQISETNDLEEAKRMSEELRELTG
DVIDEIKSLARDLRPSVLDDLGLDYALEKYLKEIQGRTGVSTEFWFQADQGLKLEPEISTNIYRIVQESVNNSIKHADAS
KIDVIVKTISSQLIVIIEDDGKGFDLEQFSDNYKQNETRGLGIFGMEERAELIGGHLAIESTPGDGTAVYLKINLAKEET
SNHDYFGTSS

Sequences:

>Translated_490_residues
MINKIKNKIGIKEKIIAIVVIIVLMLGIWTVVQVRSTTSSALNEYLQRHGISIAKNVSTRSENYLLTNDRYRLHQLVSET
MDNNSDVEYLFIEGAGGTVEISSFANELPDNLKQVNTVEENEEYNIQPLNTEHGLVYDIAVPIFEGRIGTVRLGMSTSEI
DQLVHQICSNIWLTVLIVSIVGLITAYLLSLIIINPIYRLVSATEQVAKGHLHGIPLVVTNDEIGKLSLSFKKMIEGLKS
LRENNESCWVQLEKKEEMRKKLLNKMMSAQEEERKKISRELHDGTGQSLTTLKLALKQISETNDLEEAKRMSEELRELTG
DVIDEIKSLARDLRPSVLDDLGLDYALEKYLKEIQGRTGVSTEFWFQADQGLKLEPEISTNIYRIVQESVNNSIKHADAS
KIDVIVKTISSQLIVIIEDDGKGFDLEQFSDNYKQNETRGLGIFGMEERAELIGGHLAIESTPGDGTAVYLKINLAKEET
SNHDYFGTSS
>Mature_490_residues
MINKIKNKIGIKEKIIAIVVIIVLMLGIWTVVQVRSTTSSALNEYLQRHGISIAKNVSTRSENYLLTNDRYRLHQLVSET
MDNNSDVEYLFIEGAGGTVEISSFANELPDNLKQVNTVEENEEYNIQPLNTEHGLVYDIAVPIFEGRIGTVRLGMSTSEI
DQLVHQICSNIWLTVLIVSIVGLITAYLLSLIIINPIYRLVSATEQVAKGHLHGIPLVVTNDEIGKLSLSFKKMIEGLKS
LRENNESCWVQLEKKEEMRKKLLNKMMSAQEEERKKISRELHDGTGQSLTTLKLALKQISETNDLEEAKRMSEELRELTG
DVIDEIKSLARDLRPSVLDDLGLDYALEKYLKEIQGRTGVSTEFWFQADQGLKLEPEISTNIYRIVQESVNNSIKHADAS
KIDVIVKTISSQLIVIIEDDGKGFDLEQFSDNYKQNETRGLGIFGMEERAELIGGHLAIESTPGDGTAVYLKINLAKEET
SNHDYFGTSS

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=239, Percent_Identity=29.7071129707113, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788812, Length=215, Percent_Identity=29.7674418604651, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787474, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55058; Mature: 55058

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKIKNKIGIKEKIIAIVVIIVLMLGIWTVVQVRSTTSSALNEYLQRHGISIAKNVSTR
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
SENYLLTNDRYRLHQLVSETMDNNSDVEYLFIEGAGGTVEISSFANELPDNLKQVNTVEE
CCCEEEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHCCHHHHHHCCCCC
NEEYNIQPLNTEHGLVYDIAVPIFEGRIGTVRLGMSTSEIDQLVHQICSNIWLTVLIVSI
CCCCCCEECCCCCCEEEEEECHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VGLITAYLLSLIIINPIYRLVSATEQVAKGHLHGIPLVVTNDEIGKLSLSFKKMIEGLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LRENNESCWVQLEKKEEMRKKLLNKMMSAQEEERKKISRELHDGTGQSLTTLKLALKQIS
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ETNDLEEAKRMSEELRELTGDVIDEIKSLARDLRPSVLDDLGLDYALEKYLKEIQGRTGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCC
STEFWFQADQGLKLEPEISTNIYRIVQESVNNSIKHADASKIDVIVKTISSQLIVIIEDD
CCCEEEECCCCCEECCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEECC
GKGFDLEQFSDNYKQNETRGLGIFGMEERAELIGGHLAIESTPGDGTAVYLKINLAKEET
CCCCCHHHHHHHHCCCCCCCCCEECHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCC
SNHDYFGTSS
CCCCCCCCCC
>Mature Secondary Structure
MINKIKNKIGIKEKIIAIVVIIVLMLGIWTVVQVRSTTSSALNEYLQRHGISIAKNVSTR
CCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
SENYLLTNDRYRLHQLVSETMDNNSDVEYLFIEGAGGTVEISSFANELPDNLKQVNTVEE
CCCEEEECCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEHHHHHHHCCHHHHHHCCCCC
NEEYNIQPLNTEHGLVYDIAVPIFEGRIGTVRLGMSTSEIDQLVHQICSNIWLTVLIVSI
CCCCCCEECCCCCCEEEEEECHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VGLITAYLLSLIIINPIYRLVSATEQVAKGHLHGIPLVVTNDEIGKLSLSFKKMIEGLKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LRENNESCWVQLEKKEEMRKKLLNKMMSAQEEERKKISRELHDGTGQSLTTLKLALKQIS
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ETNDLEEAKRMSEELRELTGDVIDEIKSLARDLRPSVLDDLGLDYALEKYLKEIQGRTGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHCCCCCC
STEFWFQADQGLKLEPEISTNIYRIVQESVNNSIKHADASKIDVIVKTISSQLIVIIEDD
CCCEEEECCCCCEECCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCEEEEEECC
GKGFDLEQFSDNYKQNETRGLGIFGMEERAELIGGHLAIESTPGDGTAVYLKINLAKEET
CCCCCHHHHHHHHCCCCCCCCCEECHHHHHHHHCCEEEEECCCCCCEEEEEEEEEECCCC
SNHDYFGTSS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA