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The map label for this gene is nreC [H]

Identifier: 188585286

GI number: 188585286

Start: 671794

End: 672441

Strand: Reverse

Name: nreC [H]

Synonym: Nther_0648

Alternate gene names: 188585286

Gene position: 672441-671794 (Counterclockwise)

Preceding gene: 188585287

Following gene: 188585276

Centisome position: 21.24

GC content: 37.04

Gene sequence:

>648_bases
ATGACTATTTCGGTACTAGTAGTTGATGATCATGCCGTACTTGGAAAAGGATTGAGTATGCTTTTAAATTCCCAAGATGA
TATGGAGGTATGTGGGCAAGTTGGTACTGCCAAAGAAGCTTTAGATACATGCAAGGAAAAATGTCCCGATGTAGTATTAC
TGGATCTGTCACTCCCAGATAAACAGGGTCATGAAATAATCAAAGAACTCAAAGAATCTTGTAGTGCCCGAGTTTTGGCA
CTGACAATGCACGAAGATGAAGCTTATTTCAAAAGAGTGGTTGAAGCAGGAGGAGATGGGTATATTTTAAAAAAAGCAGC
TGATGACGAATTGATTTCAGCCATCAGGTCAGTTTATCAAGGAGAAGTTATTGTAGATAAAACTTTTACTAAATTATTAA
TCGACTATTATCGAAACCCAGATAAACAGAGCGGTACAGAAAAAAACTATGATCTCAGCGACAGGGAAAAGGAAGTATTG
CAGCTAATAGCCTTAGGATATACCAATAAAGAAATTGCCGAGAAATTATATATAAGCATAAAAACGGTGGAAACCCATAT
TGCAAGAATAAAAGAAAAATTAGGCCTTAACCGCAGATCCGAGCTAGTCCGATATGCAATGAGAAATAATATAATCAGTA
CCGAGTGA

Upstream 100 bases:

>100_bases
GCAGAATTAATTGGGGGACATTTGGCGATTGAAAGCACTCCCGGAGATGGTACTGCCGTTTATTTAAAGATTAATTTAGC
AAAGGAGGAAACATCAAACC

Downstream 100 bases:

>100_bases
AGCTAGATAGAATTTAATCTTTATCTTACTTCTTTATTAAAATTCTTTAGCAAAATTTTTTATTAAAATTCTATTTCGGA
TTTTTTCAAACAGGGATTAC

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTISVLVVDDHAVLGKGLSMLLNSQDDMEVCGQVGTAKEALDTCKEKCPDVVLLDLSLPDKQGHEIIKELKESCSARVLA
LTMHEDEAYFKRVVEAGGDGYILKKAADDELISAIRSVYQGEVIVDKTFTKLLIDYYRNPDKQSGTEKNYDLSDREKEVL
QLIALGYTNKEIAEKLYISIKTVETHIARIKEKLGLNRRSELVRYAMRNNIISTE

Sequences:

>Translated_215_residues
MTISVLVVDDHAVLGKGLSMLLNSQDDMEVCGQVGTAKEALDTCKEKCPDVVLLDLSLPDKQGHEIIKELKESCSARVLA
LTMHEDEAYFKRVVEAGGDGYILKKAADDELISAIRSVYQGEVIVDKTFTKLLIDYYRNPDKQSGTEKNYDLSDREKEVL
QLIALGYTNKEIAEKLYISIKTVETHIARIKEKLGLNRRSELVRYAMRNNIISTE
>Mature_214_residues
TISVLVVDDHAVLGKGLSMLLNSQDDMEVCGQVGTAKEALDTCKEKCPDVVLLDLSLPDKQGHEIIKELKESCSARVLAL
TMHEDEAYFKRVVEAGGDGYILKKAADDELISAIRSVYQGEVIVDKTFTKLLIDYYRNPDKQSGTEKNYDLSDREKEVLQ
LIALGYTNKEIAEKLYISIKTVETHIARIKEKLGLNRRSELVRYAMRNNIISTE

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=32.093023255814, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=30.6930693069307, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI1788521, Length=199, Percent_Identity=31.1557788944724, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=26.4705882352941, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787473, Length=186, Percent_Identity=30.6451612903226, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788712, Length=213, Percent_Identity=28.169014084507, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=28.3653846153846, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24170; Mature: 24039

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISVLVVDDHAVLGKGLSMLLNSQDDMEVCGQVGTAKEALDTCKEKCPDVVLLDLSLPD
CEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCC
KQGHEIIKELKESCSARVLALTMHEDEAYFKRVVEAGGDGYILKKAADDELISAIRSVYQ
CCHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHC
GEVIVDKTFTKLLIDYYRNPDKQSGTEKNYDLSDREKEVLQLIALGYTNKEIAEKLYISI
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
KTVETHIARIKEKLGLNRRSELVRYAMRNNIISTE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TISVLVVDDHAVLGKGLSMLLNSQDDMEVCGQVGTAKEALDTCKEKCPDVVLLDLSLPD
EEEEEEECCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCC
KQGHEIIKELKESCSARVLALTMHEDEAYFKRVVEAGGDGYILKKAADDELISAIRSVYQ
CCHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHC
GEVIVDKTFTKLLIDYYRNPDKQSGTEKNYDLSDREKEVLQLIALGYTNKEIAEKLYISI
CCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
KTVETHIARIKEKLGLNRRSELVRYAMRNNIISTE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]