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The map label for this gene is 188585278

Identifier: 188585278

GI number: 188585278

Start: 663242

End: 663775

Strand: Direct

Name: 188585278

Synonym: Nther_0640

Alternate gene names: NA

Gene position: 663242-663775 (Clockwise)

Preceding gene: 188585277

Following gene: 188585279

Centisome position: 20.95

GC content: 35.21

Gene sequence:

>534_bases
ATGACAGAATCCAATATTTTATTGACTGGTAAACCCGGTATTGGAAAGACCACCGTGATTAAAAGAACTGTAGAACTTCT
TTCATGTTCAAGTACTGGTTTTTATACCCGTGAAATTAAAAGGGGTGATCCCCGGGTTGGATTTGAAATAATATCTTTAC
AAACTGGAGAGAGATTACCTTTAGCTCATACTGATTTTACCACTGCTGAAGATAGAGTAGGAAAATACGGTGTAAAAGCT
GAAAACCTGCTTGGATTCTTAAAGGAAATTAATGAAGCTATGACTAGTAACAAACCTCAATGCCTGGTGATAGATGAAAT
TGGAAAAATGGAATTTTTCACTCCCGGTTTTCATGAAACCGTGGATAAAGCTTTTCAAAGTTCTTATCCCTTGTTGGCAA
CTATTATGAAAAAGTCTCATAAATTCTGTGATTATTTGAAAAACAGAGGTGATACTGATGTTATTGAGGTTACGGAGAAT
AACAGGGATGACTTACCAGAAAAGTTAGCAAAACGTATAGAAGAGCAATTATAA

Upstream 100 bases:

>100_bases
CAACCTTACACAAAATTCGTTCAATCGAAGAGTTCAACTATCAACAACGGAGTATAAAAGAGCCTTGATTTAAGCCTTAG
TTTGGATATGGGGTGATCTT

Downstream 100 bases:

>100_bases
AATCTAGGAGGTGTTTTTATGCGGATAGGATTAATCAGTGATACTCATGGCAGTTTAAAAGCCTGGAATCAAGCTATGGA
ACTATTTCAAGATTGTCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MTESNILLTGKPGIGKTTVIKRTVELLSCSSTGFYTREIKRGDPRVGFEIISLQTGERLPLAHTDFTTAEDRVGKYGVKA
ENLLGFLKEINEAMTSNKPQCLVIDEIGKMEFFTPGFHETVDKAFQSSYPLLATIMKKSHKFCDYLKNRGDTDVIEVTEN
NRDDLPEKLAKRIEEQL

Sequences:

>Translated_177_residues
MTESNILLTGKPGIGKTTVIKRTVELLSCSSTGFYTREIKRGDPRVGFEIISLQTGERLPLAHTDFTTAEDRVGKYGVKA
ENLLGFLKEINEAMTSNKPQCLVIDEIGKMEFFTPGFHETVDKAFQSSYPLLATIMKKSHKFCDYLKNRGDTDVIEVTEN
NRDDLPEKLAKRIEEQL
>Mature_176_residues
TESNILLTGKPGIGKTTVIKRTVELLSCSSTGFYTREIKRGDPRVGFEIISLQTGERLPLAHTDFTTAEDRVGKYGVKAE
NLLGFLKEINEAMTSNKPQCLVIDEIGKMEFFTPGFHETVDKAFQSSYPLLATIMKKSHKFCDYLKNRGDTDVIEVTENN
RDDLPEKLAKRIEEQL

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family

Homologues:

Organism=Homo sapiens, GI14150100, Length=178, Percent_Identity=35.9550561797753, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI85726488, Length=182, Percent_Identity=30.2197802197802, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPTH_NATTJ (B2A6V4)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916823.1
- ProteinModelPortal:   B2A6V4
- SMR:   B2A6V4
- GeneID:   6315191
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0640
- HOGENOM:   HBG574935
- OMA:   TKENRNH
- HAMAP:   MF_00796
- InterPro:   IPR004948

Pfam domain/function: PF03266 DUF265

EC number: =3.6.1.15

Molecular weight: Translated: 19950; Mature: 19819

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESNILLTGKPGIGKTTVIKRTVELLSCSSTGFYTREIKRGDPRVGFEIISLQTGERLP
CCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCCCEEEEEECCCCCCC
LAHTDFTTAEDRVGKYGVKAENLLGFLKEINEAMTSNKPQCLVIDEIGKMEFFTPGFHET
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCHHHH
VDKAFQSSYPLLATIMKKSHKFCDYLKNRGDTDVIEVTENNRDDLPEKLAKRIEEQL
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TESNILLTGKPGIGKTTVIKRTVELLSCSSTGFYTREIKRGDPRVGFEIISLQTGERLP
CCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEHHHCCCCCCCCEEEEEECCCCCCC
LAHTDFTTAEDRVGKYGVKAENLLGFLKEINEAMTSNKPQCLVIDEIGKMEFFTPGFHET
CCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCHHHH
VDKAFQSSYPLLATIMKKSHKFCDYLKNRGDTDVIEVTENNRDDLPEKLAKRIEEQL
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA