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The map label for this gene is yqkF [H]

Identifier: 188585214

GI number: 188585214

Start: 604770

End: 605825

Strand: Direct

Name: yqkF [H]

Synonym: Nther_0576

Alternate gene names: 188585214

Gene position: 604770-605825 (Clockwise)

Preceding gene: 188585211

Following gene: 188585216

Centisome position: 19.1

GC content: 35.51

Gene sequence:

>1056_bases
ATGACCATAAGTAGAAGGACTTTTTTAAAAATTGGCGGTGTTGTGATAGCTGGTAGTGTAATTTATGTAATCAATTCGGA
AATATTTCCTGAAAAAGATCAAGATTCATCTCCACATTATAATAATTTAAAAGATAATGAAGATTCCGTCAAGCTAAATG
CTGACAAAAACAAAGATCCGAATCCTGCTAACAAGGAACATCAAAACATGATACCCAGAAGAAAACTGGGAAAAACTGAA
AGATCGGTTAGTTTATTGGGATTAGGTGGAGGAGGGATTCTGGCTCAAGAAGGGAATGAATCTCAAGAAGAGATCCAAGA
ATTGATTCAAAAAGCCGTCGACAATGGTATTAATTTTATTGATACTGCTCCCACTTATGGTCCCAGTGAAGAAAACATAG
GAACTGCTTTAGAAGGACTAGCAATAGACCGATCCGAGTTGTTTATTGCTACTAAAACCTTATCTAGATCTTATGACGAA
ACTATGAAACTAGTGGAAGAAAGCCTTAACAGATTAAAAACTGATTATATAGACCTATACCAAATTCATGGTATAAATGG
TCAAGAAGATTTAGAAGAAGCTTTTTCTCAAGATGGATCTATCCAAGCTTTAGAGAAATTAAAACAAGAGGGTGTTATTA
AATCTACCGGGGTTAGCGGTCATCGTGAACCAAGAGTGTTAATGGACGCTCTAGAAGAGTATGACTTTGACTGTATTATG
ATGCCACTAAACGCAGGAGATATCCATGACCGGCCTTTTCAAACTAAGCTTTTAAATAAAGCCCGGGATAGGAATATGGG
GATAATAGCCATGAAAGTAATGGCTTACGGCAACATATTTAATGAAGAGGGGATTAGAAAAGCGGAACAGGCACTTTCTT
ACACCTGTTCCTTTCCCATAAGTACTGCTATTATTGGAATATCCCAAATCAATCAATTAGAAGACAATATCCAGATTTTG
AAAAATTTTTCACCTTTAGAGAACCATGATTTAGAAAAGCTTGAACAATTGACTGAACATTATCAGGATAAAATAAATCA
TTTTAGAGATTGGTAG

Upstream 100 bases:

>100_bases
ATAATTTTGTCAGAAAAGTTTCAGAAAGTCAAAGAGGGATCTTGGAGAAGATCTTTCATGATCTCAATGAGTGATTTTAA
TGTGGAGGGATGGTTGTTAA

Downstream 100 bases:

>100_bases
TTAGCAAGTTATTCAATATCAATTTCATGGGAGTCACCATGGCTGTTAGGCTCATTTTTGAGAGGTAGTTTGACGTTCAG
GATACCTTTATCATAGGTGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTISRRTFLKIGGVVIAGSVIYVINSEIFPEKDQDSSPHYNNLKDNEDSVKLNADKNKDPNPANKEHQNMIPRRKLGKTE
RSVSLLGLGGGGILAQEGNESQEEIQELIQKAVDNGINFIDTAPTYGPSEENIGTALEGLAIDRSELFIATKTLSRSYDE
TMKLVEESLNRLKTDYIDLYQIHGINGQEDLEEAFSQDGSIQALEKLKQEGVIKSTGVSGHREPRVLMDALEEYDFDCIM
MPLNAGDIHDRPFQTKLLNKARDRNMGIIAMKVMAYGNIFNEEGIRKAEQALSYTCSFPISTAIIGISQINQLEDNIQIL
KNFSPLENHDLEKLEQLTEHYQDKINHFRDW

Sequences:

>Translated_351_residues
MTISRRTFLKIGGVVIAGSVIYVINSEIFPEKDQDSSPHYNNLKDNEDSVKLNADKNKDPNPANKEHQNMIPRRKLGKTE
RSVSLLGLGGGGILAQEGNESQEEIQELIQKAVDNGINFIDTAPTYGPSEENIGTALEGLAIDRSELFIATKTLSRSYDE
TMKLVEESLNRLKTDYIDLYQIHGINGQEDLEEAFSQDGSIQALEKLKQEGVIKSTGVSGHREPRVLMDALEEYDFDCIM
MPLNAGDIHDRPFQTKLLNKARDRNMGIIAMKVMAYGNIFNEEGIRKAEQALSYTCSFPISTAIIGISQINQLEDNIQIL
KNFSPLENHDLEKLEQLTEHYQDKINHFRDW
>Mature_350_residues
TISRRTFLKIGGVVIAGSVIYVINSEIFPEKDQDSSPHYNNLKDNEDSVKLNADKNKDPNPANKEHQNMIPRRKLGKTER
SVSLLGLGGGGILAQEGNESQEEIQELIQKAVDNGINFIDTAPTYGPSEENIGTALEGLAIDRSELFIATKTLSRSYDET
MKLVEESLNRLKTDYIDLYQIHGINGQEDLEEAFSQDGSIQALEKLKQEGVIKSTGVSGHREPRVLMDALEEYDFDCIMM
PLNAGDIHDRPFQTKLLNKARDRNMGIIAMKVMAYGNIFNEEGIRKAEQALSYTCSFPISTAIIGISQINQLEDNIQILK
NFSPLENHDLEKLEQLTEHYQDKINHFRDW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081735, Length=294, Percent_Identity=29.9319727891156, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082198, Length=141, Percent_Identity=34.7517730496454, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=345, Percent_Identity=24.3478260869565, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788081, Length=152, Percent_Identity=30.2631578947368, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=314, Percent_Identity=23.5668789808917, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323684, Length=166, Percent_Identity=37.9518072289157, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646155, Length=160, Percent_Identity=38.125, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=162, Percent_Identity=32.7160493827161, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=192, Percent_Identity=30.7291666666667, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39532; Mature: 39401

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISRRTFLKIGGVVIAGSVIYVINSEIFPEKDQDSSPHYNNLKDNEDSVKLNADKNKDP
CCCCHHHHHHHCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
NPANKEHQNMIPRRKLGKTERSVSLLGLGGGGILAQEGNESQEEIQELIQKAVDNGINFI
CCCCCHHHHCCCHHHHCCCHHCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCCEE
DTAPTYGPSEENIGTALEGLAIDRSELFIATKTLSRSYDETMKLVEESLNRLKTDYIDLY
ECCCCCCCCCCCHHHHHHHHEECCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
QIHGINGQEDLEEAFSQDGSIQALEKLKQEGVIKSTGVSGHREPRVLMDALEEYDFDCIM
EEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCEEE
MPLNAGDIHDRPFQTKLLNKARDRNMGIIAMKVMAYGNIFNEEGIRKAEQALSYTCSFPI
EECCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHCCHHCHHHHHHHHHHHHHCCCCCH
STAIIGISQINQLEDNIQILKNFSPLENHDLEKLEQLTEHYQDKINHFRDW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TISRRTFLKIGGVVIAGSVIYVINSEIFPEKDQDSSPHYNNLKDNEDSVKLNADKNKDP
CCCHHHHHHHCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
NPANKEHQNMIPRRKLGKTERSVSLLGLGGGGILAQEGNESQEEIQELIQKAVDNGINFI
CCCCCHHHHCCCHHHHCCCHHCEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHCCCCEE
DTAPTYGPSEENIGTALEGLAIDRSELFIATKTLSRSYDETMKLVEESLNRLKTDYIDLY
ECCCCCCCCCCCHHHHHHHHEECCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
QIHGINGQEDLEEAFSQDGSIQALEKLKQEGVIKSTGVSGHREPRVLMDALEEYDFDCIM
EEECCCCHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHCCCCEEE
MPLNAGDIHDRPFQTKLLNKARDRNMGIIAMKVMAYGNIFNEEGIRKAEQALSYTCSFPI
EECCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHCCHHCHHHHHHHHHHHHHCCCCCH
STAIIGISQINQLEDNIQILKNFSPLENHDLEKLEQLTEHYQDKINHFRDW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]