Click here to switch to the map view.

The map label for this gene is mrpC [H]

Identifier: 188585146

GI number: 188585146

Start: 530397

End: 530756

Strand: Direct

Name: mrpC [H]

Synonym: Nther_0507

Alternate gene names: 188585146

Gene position: 530397-530756 (Clockwise)

Preceding gene: 188585145

Following gene: 188585147

Centisome position: 16.76

GC content: 34.17

Gene sequence:

>360_bases
TTGGGTCTATTACAAAGCATAGCCGCTAATTACTATTTTTTGTTTGCAATTCTATTATTTTTGATTGGTATCTATACCAT
GTTGACTCATCCTAATTTATTAAAAAAGGTAATTGGGCTCAATATCATGGAAACATCAGTTTTTTTACTGTTCGTTTCTG
GTGGATATGTTGCCGGTGGACGGGCACCTATAGTCACCGGAAATGAAGAGGTATATGTAAATCCTCTTCCCCACGCATTA
ATACTAACTGGTATTGTCATAGCAATTAGTATTACTTCATTGTTACTTAGCTTAATTGTGAAAATATACAAATATTATGG
CACTTTGAATGCGGACAAAATTTCCAAAATGAGGGGTTGA

Upstream 100 bases:

>100_bases
CATGGAAACTGGTTTAATGTGGCTAATGGCTTTAAAGTAGCTCTTAGTTTGGTGAAATTATTCTACTTATTAAGTACTCT
CGAAAGCGAGGATGGTAAAA

Downstream 100 bases:

>100_bases
TTTTAATTGGAAGGCCATTTTCACCTGCCAATCATTATAGTTTTAATCGGTATTTTCGTATCATTTATATTACCGGGATT
ACATTTTATCAAAAAAAATC

Product: NADH-ubiquinone oxidoreductase chain 4L

Products: NA

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MGLLQSIAANYYFLFAILLFLIGIYTMLTHPNLLKKVIGLNIMETSVFLLFVSGGYVAGGRAPIVTGNEEVYVNPLPHAL
ILTGIVIAISITSLLLSLIVKIYKYYGTLNADKISKMRG

Sequences:

>Translated_119_residues
MGLLQSIAANYYFLFAILLFLIGIYTMLTHPNLLKKVIGLNIMETSVFLLFVSGGYVAGGRAPIVTGNEEVYVNPLPHAL
ILTGIVIAISITSLLLSLIVKIYKYYGTLNADKISKMRG
>Mature_118_residues
GLLQSIAANYYFLFAILLFLIGIYTMLTHPNLLKKVIGLNIMETSVFLLFVSGGYVAGGRAPIVTGNEEVYVNPLPHALI
LTGIVIAISITSLLLSLIVKIYKYYGTLNADKISKMRG

Specific function: Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual N

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001133 [H]

Pfam domain/function: PF00420 Oxidored_q2 [H]

EC number: NA

Molecular weight: Translated: 13010; Mature: 12879

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLQSIAANYYFLFAILLFLIGIYTMLTHPNLLKKVIGLNIMETSVFLLFVSGGYVAGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHEECCCEECCC
RAPIVTGNEEVYVNPLPHALILTGIVIAISITSLLLSLIVKIYKYYGTLNADKISKMRG
CCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
GLLQSIAANYYFLFAILLFLIGIYTMLTHPNLLKKVIGLNIMETSVFLLFVSGGYVAGG
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHEECCCEECCC
RAPIVTGNEEVYVNPLPHALILTGIVIAISITSLLLSLIVKIYKYYGTLNADKISKMRG
CCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11356194 [H]