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The map label for this gene is nudL [H]

Identifier: 188585107

GI number: 188585107

Start: 496431

End: 497039

Strand: Reverse

Name: nudL [H]

Synonym: Nther_0468

Alternate gene names: 188585107

Gene position: 497039-496431 (Counterclockwise)

Preceding gene: 188585123

Following gene: 188585105

Centisome position: 15.7

GC content: 37.77

Gene sequence:

>609_bases
ATGAATAGACCAGATATTATATCTAAATTTAATAACCGCAGTTCATCCATTATGGGTATCAAAGTCAAAAATTCTGTCCT
GCTTCCCTTAGTTTCAATCAATCAAGAGTGGCAATTGATATTTCAGGTCCGGTCTCAACAAATAAAATCCCAGCCTGGCG
AAATTTCTTTCCCTGGAGGGAAGATAGAACCGGGCGAGAGTTCACGTAATGCCGCTATTCGCGAGACATCAGAAGAGTTG
GGCATTCAAACTAATTCCATTTCCATTTGGGGACAGTTGGATCTACTGGTAACCCCCTTTAATATGATGATTGTACCTTA
TATAGGAGAAATTCATACATTACCAAAGGATTTTAACATTAACTTACAGGAAGTATCCGAAGTTTTTACCGTCCCACTAG
ATTTCTTTGTCAAGGAAAACCCTTATAAATATAGAATGCAAGTGGGAATTACACCACCCCATGATTTTCCTTTTAATTTG
GTGCCCGGTGGTAAGAACTATCCCTTTAAACAGGGGGAATACCCCTCTTATTTTTACATTTACGGTGATTACGTTATCTG
GGGGTTTACAGCCAGAATTATTAAAAACTTTATAGATAATCTATCTTAG

Upstream 100 bases:

>100_bases
TTAAAGTTATGTTTAGATAAGGTTATATCAAAGTTGAATGTGGATAGCTTTAAAATTTTTATATAAGTTAATTCCTCAAT
CATTTGAAAGGAGTTAAACT

Downstream 100 bases:

>100_bases
TTAGGATACAAATCACTTCTATATGAGTGGTTTGTGGAAACATATCAACTGGTTGAAATAATTCCGGATAATAACCAAAC
TCAATCAATTTTCCTACATC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MNRPDIISKFNNRSSSIMGIKVKNSVLLPLVSINQEWQLIFQVRSQQIKSQPGEISFPGGKIEPGESSRNAAIRETSEEL
GIQTNSISIWGQLDLLVTPFNMMIVPYIGEIHTLPKDFNINLQEVSEVFTVPLDFFVKENPYKYRMQVGITPPHDFPFNL
VPGGKNYPFKQGEYPSYFYIYGDYVIWGFTARIIKNFIDNLS

Sequences:

>Translated_202_residues
MNRPDIISKFNNRSSSIMGIKVKNSVLLPLVSINQEWQLIFQVRSQQIKSQPGEISFPGGKIEPGESSRNAAIRETSEEL
GIQTNSISIWGQLDLLVTPFNMMIVPYIGEIHTLPKDFNINLQEVSEVFTVPLDFFVKENPYKYRMQVGITPPHDFPFNL
VPGGKNYPFKQGEYPSYFYIYGDYVIWGFTARIIKNFIDNLS
>Mature_202_residues
MNRPDIISKFNNRSSSIMGIKVKNSVLLPLVSINQEWQLIFQVRSQQIKSQPGEISFPGGKIEPGESSRNAAIRETSEEL
GIQTNSISIWGQLDLLVTPFNMMIVPYIGEIHTLPKDFNINLQEVSEVFTVPLDFFVKENPYKYRMQVGITPPHDFPFNL
VPGGKNYPFKQGEYPSYFYIYGDYVIWGFTARIIKNFIDNLS

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=120, Percent_Identity=37.5, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536993, Length=176, Percent_Identity=31.25, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17510677, Length=132, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI18859683, Length=185, Percent_Identity=28.1081081081081, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 23132; Mature: 23132

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPDIISKFNNRSSSIMGIKVKNSVLLPLVSINQEWQLIFQVRSQQIKSQPGEISFPGG
CCCCHHHHHCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCC
KIEPGESSRNAAIRETSEELGIQTNSISIWGQLDLLVTPFNMMIVPYIGEIHTLPKDFNI
CCCCCCCCCCCHHHHHHHHHCEEECCEEEEEEEEEEECCCCEEEEECCCCEECCCCCCCC
NLQEVSEVFTVPLDFFVKENPYKYRMQVGITPPHDFPFNLVPGGKNYPFKQGEYPSYFYI
CHHHHHHHHHCCEEEEECCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCEEEE
YGDYVIWGFTARIIKNFIDNLS
EECEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRPDIISKFNNRSSSIMGIKVKNSVLLPLVSINQEWQLIFQVRSQQIKSQPGEISFPGG
CCCCHHHHHCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCC
KIEPGESSRNAAIRETSEELGIQTNSISIWGQLDLLVTPFNMMIVPYIGEIHTLPKDFNI
CCCCCCCCCCCHHHHHHHHHCEEECCEEEEEEEEEEECCCCEEEEECCCCEECCCCCCCC
NLQEVSEVFTVPLDFFVKENPYKYRMQVGITPPHDFPFNLVPGGKNYPFKQGEYPSYFYI
CHHHHHHHHHCCEEEEECCCCEEEEEEEECCCCCCCCCEECCCCCCCCCCCCCCCCEEEE
YGDYVIWGFTARIIKNFIDNLS
EECEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA