Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 188584884

GI number: 188584884

Start: 251102

End: 252430

Strand: Direct

Name: glmM

Synonym: Nther_0242

Alternate gene names: 188584884

Gene position: 251102-252430 (Clockwise)

Preceding gene: 188584883

Following gene: 188584886

Centisome position: 7.93

GC content: 38.3

Gene sequence:

>1329_bases
ATGCCAAAATTGTTTGGTACAGATGGAGTAAGAGGAGTAGCTAATGAAGACTTAACCCCAGAGCTTTGCTTAAAAATTGG
TAGAGCAGCAGGGGAATATTTAAAATCATACGGAGACACTGTCTTGGTTGGAAGAGACACTAGATTATCAGGCACTATGT
TGGAAGCTGCCCTTTCAGCAGGTTTAGCTTCAGTAGGTTTAAAAGTAGAGCGCCTTGGGATAGTTACAACTCCTGCAGTT
GCATTTTTAGCTAGTAGAGAAGATGTAGCCGGAGGTGCTATGATTTCGGCTTCTCATAACCCTGTTCCTGATAACGGAGT
TAAGTTTTTTGATAATAAGGGATATAAGCTCGCTGAAAGTCACGAAGAGCAGATTGAAAATTATTTAGAAAAGGAATTAT
CACGACCTACAGGTACTGATATAGGAAAAGTTTTACCCGAAAACAACAAACTAATTGAAAATTATATCCAAGAATTAATT
GACAAATATCCACTGGATTTGAGTAATTATAAAATTGTCCTGGATTGTGCTTACGGAGCCACTTATCAGATAGCACCACG
TCTATTTAAAAAACTTGGTGCCGAGATAATACCTTTACATGCAGAAAATAGAGGAGAAAAAATCAATGTGGAATGTGGCT
CTACTAATCCAGAACTGACTTCTCGAACAGTAGTGGAAGAAGGAGCAGATTTAGGGTTCTCCTTCGATGGTGACGGTGAT
AGAATTATTGCCCTAGATGAAGAGGGGAACCAGGTCAATGGTGACAAAATCATGGCTATTCTTGCCAAAGATATGAAAAG
TCGTGGAGAATTAAAGAATGATAAATTAATTGCCACTGTTATGAGTAATCTTGGCTTAAAATTAGCTTTAAAAGAATTAG
GTATAGCATTGGAAGAGACCAAGGTTGGTGACCGCAATGTCCTTAACCGAATGAGGGAGCAGGACTGTGTTTTAGGTGGA
GAACAATCAGGACATATAATTAATCTCCAAGATAACACAACCGGTGATGGTGTCTTGACTGGCCTGAAATTGATGAAGGT
CTTAATTGACACTGGTCAATCTTTAAAGCAATTGGCTTCAATAATGGAAGAACTTCCTCAATTACTAGTAAATGTAAAAG
TTTCAAACAAGGATTCTGCTATTAATTCACAGAAAGTTCAAGAAGAAAAATCTAAAGTGGAAAAGCAACTAGGCAGTAAA
GGCCGAGTACTAATTCGTCCTTCAGGAACAGAACCAGTGATTAGAGTCATGGTTGAAGGTGAAAACAGAGAGACTTTACA
TGAGGTGGCTAATCACTTAACTCAGGTGATTAAAAAAGCAGCTGAATAG

Upstream 100 bases:

>100_bases
TAAAATATAATGACAAATATTTTTTGGTACAAAAAATCTATGGGTTTTAACTGATTTTTAACTTGTGAGAACTGATTTAC
TACGAAAGGGAGTGAAACTG

Downstream 100 bases:

>100_bases
AGGAAATAGTAACGAGTCTGTTAAGTTGTTATGAAAAATAAGCTCATTTGCTCGCAAGATTTCAAAAGATTTGGCAGTCA
AGCGGCATTATTACTATGTA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MPKLFGTDGVRGVANEDLTPELCLKIGRAAGEYLKSYGDTVLVGRDTRLSGTMLEAALSAGLASVGLKVERLGIVTTPAV
AFLASREDVAGGAMISASHNPVPDNGVKFFDNKGYKLAESHEEQIENYLEKELSRPTGTDIGKVLPENNKLIENYIQELI
DKYPLDLSNYKIVLDCAYGATYQIAPRLFKKLGAEIIPLHAENRGEKINVECGSTNPELTSRTVVEEGADLGFSFDGDGD
RIIALDEEGNQVNGDKIMAILAKDMKSRGELKNDKLIATVMSNLGLKLALKELGIALEETKVGDRNVLNRMREQDCVLGG
EQSGHIINLQDNTTGDGVLTGLKLMKVLIDTGQSLKQLASIMEELPQLLVNVKVSNKDSAINSQKVQEEKSKVEKQLGSK
GRVLIRPSGTEPVIRVMVEGENRETLHEVANHLTQVIKKAAE

Sequences:

>Translated_442_residues
MPKLFGTDGVRGVANEDLTPELCLKIGRAAGEYLKSYGDTVLVGRDTRLSGTMLEAALSAGLASVGLKVERLGIVTTPAV
AFLASREDVAGGAMISASHNPVPDNGVKFFDNKGYKLAESHEEQIENYLEKELSRPTGTDIGKVLPENNKLIENYIQELI
DKYPLDLSNYKIVLDCAYGATYQIAPRLFKKLGAEIIPLHAENRGEKINVECGSTNPELTSRTVVEEGADLGFSFDGDGD
RIIALDEEGNQVNGDKIMAILAKDMKSRGELKNDKLIATVMSNLGLKLALKELGIALEETKVGDRNVLNRMREQDCVLGG
EQSGHIINLQDNTTGDGVLTGLKLMKVLIDTGQSLKQLASIMEELPQLLVNVKVSNKDSAINSQKVQEEKSKVEKQLGSK
GRVLIRPSGTEPVIRVMVEGENRETLHEVANHLTQVIKKAAE
>Mature_441_residues
PKLFGTDGVRGVANEDLTPELCLKIGRAAGEYLKSYGDTVLVGRDTRLSGTMLEAALSAGLASVGLKVERLGIVTTPAVA
FLASREDVAGGAMISASHNPVPDNGVKFFDNKGYKLAESHEEQIENYLEKELSRPTGTDIGKVLPENNKLIENYIQELID
KYPLDLSNYKIVLDCAYGATYQIAPRLFKKLGAEIIPLHAENRGEKINVECGSTNPELTSRTVVEEGADLGFSFDGDGDR
IIALDEEGNQVNGDKIMAILAKDMKSRGELKNDKLIATVMSNLGLKLALKELGIALEETKVGDRNVLNRMREQDCVLGGE
QSGHIINLQDNTTGDGVLTGLKLMKVLIDTGQSLKQLASIMEELPQLLVNVKVSNKDSAINSQKVQEEKSKVEKQLGSKG
RVLIRPSGTEPVIRVMVEGENRETLHEVANHLTQVIKKAAE

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Homo sapiens, GI31377548, Length=358, Percent_Identity=26.2569832402235, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=45.045045045045, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1788361, Length=445, Percent_Identity=27.6404494382022, Blast_Score=128, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_NATTJ (B2A4R9)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916429.1
- ProteinModelPortal:   B2A4R9
- SMR:   B2A4R9
- GeneID:   6316000
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0242
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48033; Mature: 47901

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 98-98

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLFGTDGVRGVANEDLTPELCLKIGRAAGEYLKSYGDTVLVGRDTRLSGTMLEAALSA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
GLASVGLKVERLGIVTTPAVAFLASREDVAGGAMISASHNPVPDNGVKFFDNKGYKLAES
HHHHHCCEEEEECEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCHHHH
HEEQIENYLEKELSRPTGTDIGKVLPENNKLIENYIQELIDKYPLDLSNYKIVLDCAYGA
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
TYQIAPRLFKKLGAEIIPLHAENRGEKINVECGSTNPELTSRTVVEEGADLGFSFDGDGD
CHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCC
RIIALDEEGNQVNGDKIMAILAKDMKSRGELKNDKLIATVMSNLGLKLALKELGIALEET
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEHHHHCCCHHHC
KVGDRNVLNRMREQDCVLGGEQSGHIINLQDNTTGDGVLTGLKLMKVLIDTGQSLKQLAS
CCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
IMEELPQLLVNVKVSNKDSAINSQKVQEEKSKVEKQLGSKGRVLIRPSGTEPVIRVMVEG
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEC
ENRETLHEVANHLTQVIKKAAE
CCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKLFGTDGVRGVANEDLTPELCLKIGRAAGEYLKSYGDTVLVGRDTRLSGTMLEAALSA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
GLASVGLKVERLGIVTTPAVAFLASREDVAGGAMISASHNPVPDNGVKFFDNKGYKLAES
HHHHHCCEEEEECEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCHHHH
HEEQIENYLEKELSRPTGTDIGKVLPENNKLIENYIQELIDKYPLDLSNYKIVLDCAYGA
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCC
TYQIAPRLFKKLGAEIIPLHAENRGEKINVECGSTNPELTSRTVVEEGADLGFSFDGDGD
CHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCCCEEECCCCC
RIIALDEEGNQVNGDKIMAILAKDMKSRGELKNDKLIATVMSNLGLKLALKELGIALEET
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEHHHHCCCHHHC
KVGDRNVLNRMREQDCVLGGEQSGHIINLQDNTTGDGVLTGLKLMKVLIDTGQSLKQLAS
CCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
IMEELPQLLVNVKVSNKDSAINSQKVQEEKSKVEKQLGSKGRVLIRPSGTEPVIRVMVEG
HHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEC
ENRETLHEVANHLTQVIKKAAE
CCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA