Click here to switch to the map view.

The map label for this gene is radA [H]

Identifier: 188584800

GI number: 188584800

Start: 182158

End: 183528

Strand: Direct

Name: radA [H]

Synonym: Nther_0158

Alternate gene names: 188584800

Gene position: 182158-183528 (Clockwise)

Preceding gene: 188584799

Following gene: 188584801

Centisome position: 5.75

GC content: 37.2

Gene sequence:

>1371_bases
TTGAAAAAATCGACAATATATTACATGTGTTTAGACTGTGGACATACGGAATTAAAGTGGTTAGGTAAGTGTCCTGCATG
TTCTAATTGGAATACATTTCAAAAAAAATATCAACAACCGAGCGATAATAAGCATAAATCTAACATTGGTTCATCTGAAT
CAGAACAATCTTCTCAAGTAATCACCTTGTCAGAGATTGACTTAGAAAAAGAACCTCGTATGAGTACAAGCATCGATGAA
CTTGATAGAGTTTTAGGTGGAGGTATTGTACCTGGCTCAGTAGTTCTCTTTGGAGGAGACCCTGGGATAGGTAAAAGTAC
CCTGATGTTGCAAGCCTCTCATAATTTGGATACATTAAATTTCAGTACCCTTTATGTTTCTGGTGAAGAATCACTGTCTC
AATTAAAACTAAGATGTGAAAGACTAGGACTAAACTCTGAATCCTTATTGTTTGCTTCTATCACAGACCTCAGGGAACTA
GAAAATAGATTAAATGAACAAAAACCACAAATATTAATAATTGATTCTATTCAATCATTATATACTCCTGAAATTGAAGC
CCCGCCTGGAAGTTTATCCCAAGTTAAGCACTGTGCAGCAGTTTTACACTCAGTTGCTAAAGAAAATGAAATTGCTTGTT
TGATAGTTGGGCATGTTACTAAGGCAGGCCAAATAGCCGGCCCTAAAGTTTTAGAACATATAGTAGATACTGTTTTATAC
TTTGAGGGAGATCATCATCAAGACTATAGGATATTGAGAAGCATAAAAAATAGATTCGGCCCCATAGAAATTGGTGTTTT
TGAAATGCGTCAAACTGGATTACAGGAAATTACTAACCCGTCCAAATTGTTTTTAAGGAAAAGACCAGACTACACCGTAG
GTTCTGCTATCTTACCCAGTTTAGAAGGAACAAGGGCCTTTTTGGTAGAGATTCAAGCTCTGGTCAGTACCAGTCAACTA
GGCACTCCCAGAAGAGTTGTCACAGGTATTGACAGTAACCGAGCAGCATTAATAACTGCCGTTTTAGAGAAAAAATCCGG
TTTGCACTTAGTAGGTGACGATATTTTTATTAATGTGGTTGGTGGTGCTAAAGTAGCTGAACCTGCAGCCGACTTGGCTG
TGGCTCTAAGTTTGATCTCTAGCTTTAAAGAACAAGGGTTTCCGGGAGATTTAGTTGTCATGGGAGAAATAGGTTTAACA
GGTGAAATACGATCATGTAATCAACCAGAAAAACGCCTTTTAGAAGCAGAAAGAATGGGTTTTAAAAAAGCAATATTACC
CGAAGCTTGCCGTTTAAATCATCATCAAGGAAACATTGAGATTTATCCGGTATCCTATTTGAAAGATGTTTTAGAAATAT
TATCAGGGTAG

Upstream 100 bases:

>100_bases
CATGCCTTCCCAGGCAAGCGGCGGCCAAATCTTGGTCGTCGCTTGTTGTTTTTATGGCTAAAATAGTGATATAATTTTAT
TAACAAGGGGAGTGGAAAAA

Downstream 100 bases:

>100_bases
GTGATTGCGCTTGACATATTTATCAAAATTACATGATAATAAGGAGTTTTTAGATACTCTGGCTATGCTAGCTCCCGGGA
CGGGGCTTCGAGCAGGACTT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKKSTIYYMCLDCGHTELKWLGKCPACSNWNTFQKKYQQPSDNKHKSNIGSSESEQSSQVITLSEIDLEKEPRMSTSIDE
LDRVLGGGIVPGSVVLFGGDPGIGKSTLMLQASHNLDTLNFSTLYVSGEESLSQLKLRCERLGLNSESLLFASITDLREL
ENRLNEQKPQILIIDSIQSLYTPEIEAPPGSLSQVKHCAAVLHSVAKENEIACLIVGHVTKAGQIAGPKVLEHIVDTVLY
FEGDHHQDYRILRSIKNRFGPIEIGVFEMRQTGLQEITNPSKLFLRKRPDYTVGSAILPSLEGTRAFLVEIQALVSTSQL
GTPRRVVTGIDSNRAALITAVLEKKSGLHLVGDDIFINVVGGAKVAEPAADLAVALSLISSFKEQGFPGDLVVMGEIGLT
GEIRSCNQPEKRLLEAERMGFKKAILPEACRLNHHQGNIEIYPVSYLKDVLEILSG

Sequences:

>Translated_456_residues
MKKSTIYYMCLDCGHTELKWLGKCPACSNWNTFQKKYQQPSDNKHKSNIGSSESEQSSQVITLSEIDLEKEPRMSTSIDE
LDRVLGGGIVPGSVVLFGGDPGIGKSTLMLQASHNLDTLNFSTLYVSGEESLSQLKLRCERLGLNSESLLFASITDLREL
ENRLNEQKPQILIIDSIQSLYTPEIEAPPGSLSQVKHCAAVLHSVAKENEIACLIVGHVTKAGQIAGPKVLEHIVDTVLY
FEGDHHQDYRILRSIKNRFGPIEIGVFEMRQTGLQEITNPSKLFLRKRPDYTVGSAILPSLEGTRAFLVEIQALVSTSQL
GTPRRVVTGIDSNRAALITAVLEKKSGLHLVGDDIFINVVGGAKVAEPAADLAVALSLISSFKEQGFPGDLVVMGEIGLT
GEIRSCNQPEKRLLEAERMGFKKAILPEACRLNHHQGNIEIYPVSYLKDVLEILSG
>Mature_456_residues
MKKSTIYYMCLDCGHTELKWLGKCPACSNWNTFQKKYQQPSDNKHKSNIGSSESEQSSQVITLSEIDLEKEPRMSTSIDE
LDRVLGGGIVPGSVVLFGGDPGIGKSTLMLQASHNLDTLNFSTLYVSGEESLSQLKLRCERLGLNSESLLFASITDLREL
ENRLNEQKPQILIIDSIQSLYTPEIEAPPGSLSQVKHCAAVLHSVAKENEIACLIVGHVTKAGQIAGPKVLEHIVDTVLY
FEGDHHQDYRILRSIKNRFGPIEIGVFEMRQTGLQEITNPSKLFLRKRPDYTVGSAILPSLEGTRAFLVEIQALVSTSQL
GTPRRVVTGIDSNRAALITAVLEKKSGLHLVGDDIFINVVGGAKVAEPAADLAVALSLISSFKEQGFPGDLVVMGEIGLT
GEIRSCNQPEKRLLEAERMGFKKAILPEACRLNHHQGNIEIYPVSYLKDVLEILSG

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=450, Percent_Identity=44, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50032; Mature: 50032

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSTIYYMCLDCGHTELKWLGKCPACSNWNTFQKKYQQPSDNKHKSNIGSSESEQSSQV
CCCCEEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
ITLSEIDLEKEPRMSTSIDELDRVLGGGIVPGSVVLFGGDPGIGKSTLMLQASHNLDTLN
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCEEE
FSTLYVSGEESLSQLKLRCERLGLNSESLLFASITDLRELENRLNEQKPQILIIDSIQSL
EEEEEEECHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECHHHH
YTPEIEAPPGSLSQVKHCAAVLHSVAKENEIACLIVGHVTKAGQIAGPKVLEHIVDTVLY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHE
FEGDHHQDYRILRSIKNRFGPIEIGVFEMRQTGLQEITNPSKLFLRKRPDYTVGSAILPS
ECCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHEECCCCCCCCHHHCCC
LEGTRAFLVEIQALVSTSQLGTPRRVVTGIDSNRAALITAVLEKKSGLHLVGDDIFINVV
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEECCCEEEEEE
GGAKVAEPAADLAVALSLISSFKEQGFPGDLVVMGEIGLTGEIRSCNQPEKRLLEAERMG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
FKKAILPEACRLNHHQGNIEIYPVSYLKDVLEILSG
CHHHHCCHHHHCCCCCCCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKKSTIYYMCLDCGHTELKWLGKCPACSNWNTFQKKYQQPSDNKHKSNIGSSESEQSSQV
CCCCEEEEEEEECCCHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE
ITLSEIDLEKEPRMSTSIDELDRVLGGGIVPGSVVLFGGDPGIGKSTLMLQASHNLDTLN
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCEEE
FSTLYVSGEESLSQLKLRCERLGLNSESLLFASITDLRELENRLNEQKPQILIIDSIQSL
EEEEEEECHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCEEEEECHHHH
YTPEIEAPPGSLSQVKHCAAVLHSVAKENEIACLIVGHVTKAGQIAGPKVLEHIVDTVLY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHE
FEGDHHQDYRILRSIKNRFGPIEIGVFEMRQTGLQEITNPSKLFLRKRPDYTVGSAILPS
ECCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCHHHHEECCCCCCCCHHHCCC
LEGTRAFLVEIQALVSTSQLGTPRRVVTGIDSNRAALITAVLEKKSGLHLVGDDIFINVV
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEECCCEEEEEE
GGAKVAEPAADLAVALSLISSFKEQGFPGDLVVMGEIGLTGEIRSCNQPEKRLLEAERMG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
FKKAILPEACRLNHHQGNIEIYPVSYLKDVLEILSG
CHHHHCCHHHHCCCCCCCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]