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The map label for this gene is tagO [H]

Identifier: 188528372

GI number: 188528372

Start: 1601021

End: 1602019

Strand: Reverse

Name: tagO [H]

Synonym: HPSH_08230

Alternate gene names: 188528372

Gene position: 1602019-1601021 (Counterclockwise)

Preceding gene: 188528377

Following gene: 188528371

Centisome position: 99.59

GC content: 39.74

Gene sequence:

>999_bases
GTGCTATATTTTCTAACCAGTCTTTTCATTTGCTCTTTAATTGTTTTGTGGTCTAAAAAATCCACGCTCTTTGTGGATAA
CGCTAATAAAATACAAGGCTTTCATCATGCAAGAACCCCACGAGCCGGGGGGCTTGGGATCTTTCTTTCTTTTGCGTTGG
CTTGTTATTCTGAACCTTTTGAAACGCCTTTTAAGGGGTTTTTTGTTTTTTTGGGGCTGTTGTTAGTCTTTTTAAGCGGT
TTTTTAGAAGACATTAACTTTTCACTCAGCCCCAAAATACGCCTTATTTTGCAAGCTGTAGGGGTCGTTTGCATCATCTC
ATCAACGCCTTTAGTGGTGAGCGATTTTTCGCCCCTTTTTAGCTTGCCTTATTTTATCGCTTTTTTATTCGCTGTTTTTA
TGCTAGTGGGCATCAGTAACGCTATTAATATTATTGATGGGTTTAACGGGCTTGCGTCAGGGATTTGCACGATTGCGCTT
TTAGTCATTCATTATATAGACCCTAGCAATTTGTCTTGTTTGCTGGCTTACATGGTGCTTGGGTTTATGGTGTTAAATTT
CCCTTTAGGAAAGATTTTTTTAGGCGATGGGGGGGCGTATTTTTTGGGCTTGGTGTGCGGGATTTCCCTTTTGAATTTGA
GTTTAGAGCAAAAAATCAGCGTGTTTTTTGGACTCAATTTAATGCTTTATCCGGTTATAGAGGTGCTTTTTAGTATCCTT
AGGCGCAAAATAAAACGCCAAAAAGCCACCATGCCGGATAATTTGCATTTGCACACCCTTTTATTCCAATTCTTGCAACG
GCGCTCTTTGGGTTACCCCAATTCTCTATGCGCGTTTATCCTTATTCTGTGCAACCTGCCTTTTATTTTTTTAAGCGTCT
TTTTTCGCTCAAACGCTTATGCGCTCATTATCATTAGCCTAGTCTTTATCGCATGCTATTTAATAGGCTATGCTTATTTG
AACAGGCGGGTTTATGCTTCAGAAAAGCGAGCGTTTTAA

Upstream 100 bases:

>100_bases
AAAACCCACCTCTTACACCTATAAGATTTTATCATCACGCTATCTTTTGCTATAATACCCAAAACAAAATGCCAATTAAA
TCCAATAAAAAGTGTTGTGG

Downstream 100 bases:

>100_bases
TGAAAAAACTCAAAGGTCTTTTTTTGAGCCTACTCTTATGGGTCTATCCTTTAAGGAGTGAGCCGATCAATGAGGGGGCA
TACATTTTAGAAGAGATCGG

Product: undecaprenyl phosphate N-acetylglucosaminyltransferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFALACYSEPFETPFKGFFVFLGLLLVFLSG
FLEDINFSLSPKIRLILQAVGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAVFMLVGISNAINIIDGFNGLASGICTIAL
LVIHYIDPSNLSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLVCGISLLNLSLEQKISVFFGLNLMLYPVIEVLFSIL
RRKIKRQKATMPDNLHLHTLLFQFLQRRSLGYPNSLCAFILILCNLPFIFLSVFFRSNAYALIIISLVFIACYLIGYAYL
NRRVYASEKRAF

Sequences:

>Translated_332_residues
MLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFALACYSEPFETPFKGFFVFLGLLLVFLSG
FLEDINFSLSPKIRLILQAVGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAVFMLVGISNAINIIDGFNGLASGICTIAL
LVIHYIDPSNLSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLVCGISLLNLSLEQKISVFFGLNLMLYPVIEVLFSIL
RRKIKRQKATMPDNLHLHTLLFQFLQRRSLGYPNSLCAFILILCNLPFIFLSVFFRSNAYALIIISLVFIACYLIGYAYL
NRRVYASEKRAF
>Mature_332_residues
MLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFALACYSEPFETPFKGFFVFLGLLLVFLSG
FLEDINFSLSPKIRLILQAVGVVCIISSTPLVVSDFSPLFSLPYFIAFLFAVFMLVGISNAINIIDGFNGLASGICTIAL
LVIHYIDPSNLSCLLAYMVLGFMVLNFPLGKIFLGDGGAYFLGLVCGISLLNLSLEQKISVFFGLNLMLYPVIEVLFSIL
RRKIKRQKATMPDNLHLHTLLFQFLQRRSLGYPNSLCAFILILCNLPFIFLSVFFRSNAYALIIISLVFIACYLIGYAYL
NRRVYASEKRAF

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=281, Percent_Identity=26.3345195729537, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 37154; Mature: 37154

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFALACYSEPF
CHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCC
ETPFKGFFVFLGLLLVFLSGFLEDINFSLSPKIRLILQAVGVVCIISSTPLVVSDFSPLF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEECCCHHH
SLPYFIAFLFAVFMLVGISNAINIIDGFNGLASGICTIALLVIHYIDPSNLSCLLAYMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GFMVLNFPLGKIFLGDGGAYFLGLVCGISLLNLSLEQKISVFFGLNLMLYPVIEVLFSIL
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRKIKRQKATMPDNLHLHTLLFQFLQRRSLGYPNSLCAFILILCNLPFIFLSVFFRSNAY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCH
ALIIISLVFIACYLIGYAYLNRRVYASEKRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLYFLTSLFICSLIVLWSKKSTLFVDNANKIQGFHHARTPRAGGLGIFLSFALACYSEPF
CHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHCCCCCCCCHHHHHHHHHHHHCCCC
ETPFKGFFVFLGLLLVFLSGFLEDINFSLSPKIRLILQAVGVVCIISSTPLVVSDFSPLF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCEEEECCCHHH
SLPYFIAFLFAVFMLVGISNAINIIDGFNGLASGICTIALLVIHYIDPSNLSCLLAYMVL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
GFMVLNFPLGKIFLGDGGAYFLGLVCGISLLNLSLEQKISVFFGLNLMLYPVIEVLFSIL
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRKIKRQKATMPDNLHLHTLLFQFLQRRSLGYPNSLCAFILILCNLPFIFLSVFFRSNAY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCH
ALIIISLVFIACYLIGYAYLNRRVYASEKRAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]