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The map label for this gene is coaD

Identifier: 188528245

GI number: 188528245

Start: 1467397

End: 1467870

Strand: Reverse

Name: coaD

Synonym: HPSH_07555

Alternate gene names: 188528245

Gene position: 1467870-1467397 (Counterclockwise)

Preceding gene: 188528246

Following gene: 188528244

Centisome position: 91.25

GC content: 40.93

Gene sequence:

>474_bases
ATGCAAAAAATCGGCATTTACCCGGGCACTTTTGATCCGGTCACTAACGGGCATATAGACATCATCCACCGATCTAGCGA
ATTGTTTGAAAAGCTCATTGTCGCTGTGGCGTATTCTTGCGCTAAAAACCCCATGTTTAGTTTGAAAGAGCGCTTAGAAA
TGATACAGCTTGCCACTAAAGGTTTTAAAAATGTAGAATGCGTGGCGTTTGAAGGGCTATTAGCCAATCTGGCTAAAGAA
TATCATTGTAAGGTGCTAGTTAGGGGATTAAGGGTGGTGAGCGATTTTGAATACGAATTGCAAATGGGCTATGCGAACAA
ATCCTTAAACCACGAATTAGAAACCTTGTATTTCATGCCCACTTTACAAAACGCTTTCATAAGCTCTTCTATCGTGCGAT
CCATTATCGCGCATAAGGGCGATGCGAGTCATTTAGTGCCTAAAGAAATTCACCCTTTTATTTCAAAGGTTTAA

Upstream 100 bases:

>100_bases
AGAGCAAGACTTTAGAAGCGATGCAAGATTTTTTAGTGGGGAAGTGGTTTGACAGCTTAGGGATAGAAAATGACTTATAC
CCACGATGGGGAATGAACTG

Downstream 100 bases:

>100_bases
AATGTATGTGGTGTTAGAAGGCGTTGATGGCGCGGGCAAAAGCACTCAAGTAGGATTATTAAAAGACAGGTTTAAAAACG
CCCTTGTTACCAAAGAGCCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATKGFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV

Sequences:

>Translated_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATKGFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV
>Mature_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATKGFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=50.3311258278146, Blast_Score=180, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17730; Mature: 17730

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAYSCAKNPMFSLKERLEMIQLATK
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHHEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIHPFISKV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA