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The map label for this gene is 188528196

Identifier: 188528196

GI number: 188528196

Start: 1423889

End: 1424998

Strand: Reverse

Name: 188528196

Synonym: HPSH_07300

Alternate gene names: NA

Gene position: 1424998-1423889 (Counterclockwise)

Preceding gene: 188528197

Following gene: 188528194

Centisome position: 88.59

GC content: 32.43

Gene sequence:

>1110_bases
ATGCTGCCCTTAAATTGGCAAAGAGTGAGGCTTGGGGATATAGGCAAACCATGCATGTGTAAAAGAGTGATGAAGCATCA
AACAACACGATATGGTGAAATTCCATTCTATAAAATAGGCACATTTGGCAACACCGCTGATGCCTTTATTTCAAAAAAGC
TATTTTTAGAATACAAAACAAAATATTCTTTTCCAAAAAAAGGCGATATTTTAATTTCTGCTTCCGGAACTATTGGTAGG
GCAGTCATTTATGACGGAAAACCCGCTTATTTTCAAGACTCAAATATCGTTTGGATTGACAACGATGAAACATTAGTAAA
AAATGATTTTTTATTTTATGCTTATTCCAATGTTAAATGGAATACAGAGCATACAACTATCTTAAGACTTTATAATGATA
ATTTTAGAAATACTTTAATCCCCCTACCCCCCCTAAACGAACAAATCGCTATCGCTAACATTTTAAGCGCTTTGGATCAT
TATCTTTATGCATTAGACGCTCTCATTCTTAAAAAAGAGAGCGTTAAAAAAGCTCTAAGCTTTGAACTATTGAGCCAAAG
AAAACGCTTGAAAGGCTTCAATCAAGCATGGCAAAGAGTGAGGCTTGGGGATATTGCCAACTATTTAACATCAAATTTAA
GTGTAGAACAAATCACGCAACAAGGAAAAATTAAAGTCTATGATGTGAATAATTTCATAGGCTATACAGATACAACTTTC
ATTAGTGATAAGCCTTATATTTCTATTGTCAAAGATGGAAGTGTAGGCAGAGTAAGGATTTTGCCACCTAAAACAAATAT
TTTATCTACTATGGGAGCGTTAATTGCTAATCATAGAACAACAACAGAGTTTTTATTTTATTTGTTATCTAATTTTGATT
TTAAAAATTTCACAAGCGGTAGCATAATACCGCATATTTATTTCAAAGATTATAAAGAAAAGACTATTTTTTTACCCCCT
CTAAACGAACAAATCGCTATCGCTAACATTTTAAGCGATTTGGATAATGAGATCGCCAGCCTTAAAAACAAAAAACGCCA
ATTTGAAAACATCAAAAAAGCTTTAAACCACGATTTAATGAGCGCTAAAATTAGGGTTTTAAAAAAATAA

Upstream 100 bases:

>100_bases
TATAGAAAAACTGGTTTTGGCTAGGGCTTTAAAACTGGTTTTAGAAGATCGGGTGTTTGTGCATGAAAATAAAACGGTGG
TGTTTTGAATGCTTCCATTA

Downstream 100 bases:

>100_bases
ACGCCCCAAAAGTCAAGGACAAACCCGCTTCGCAAAGCAAACCCTAAGCTTTTAAGCTCAGGGGAACTTTGGCTAATAAT
TACTTTTCTATAGAAAAGAT

Product: type I R-M system specificity subunit

Products: NA

Alternate protein names: S protein [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASGTIGR
AVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSALDH
YLYALDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDIANYLTSNLSVEQITQQGKIKVYDVNNFIGYTDTTF
ISDKPYISIVKDGSVGRVRILPPKTNILSTMGALIANHRTTTEFLFYLLSNFDFKNFTSGSIIPHIYFKDYKEKTIFLPP
LNEQIAIANILSDLDNEIASLKNKKRQFENIKKALNHDLMSAKIRVLKK

Sequences:

>Translated_369_residues
MLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASGTIGR
AVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSALDH
YLYALDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDIANYLTSNLSVEQITQQGKIKVYDVNNFIGYTDTTF
ISDKPYISIVKDGSVGRVRILPPKTNILSTMGALIANHRTTTEFLFYLLSNFDFKNFTSGSIIPHIYFKDYKEKTIFLPP
LNEQIAIANILSDLDNEIASLKNKKRQFENIKKALNHDLMSAKIRVLKK
>Mature_369_residues
MLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKTKYSFPKKGDILISASGTIGR
AVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKWNTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSALDH
YLYALDALILKKESVKKALSFELLSQRKRLKGFNQAWQRVRLGDIANYLTSNLSVEQITQQGKIKVYDVNNFIGYTDTTF
ISDKPYISIVKDGSVGRVRILPPKTNILSTMGALIANHRTTTEFLFYLLSNFDFKNFTSGSIIPHIYFKDYKEKTIFLPP
LNEQIAIANILSDLDNEIASLKNKKRQFENIKKALNHDLMSAKIRVLKK

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 42454; Mature: 42454

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKT
CCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHEEEHH
KYSFPKKGDILISASGTIGRAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKW
CCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCEEEEECCCCEEEECCEEEEEEECEEE
NTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSALDHYLYALDALILKKESVKKALS
CCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FELLSQRKRLKGFNQAWQRVRLGDIANYLTSNLSVEQITQQGKIKVYDVNNFIGYTDTTF
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCCEE
ISDKPYISIVKDGSVGRVRILPPKTNILSTMGALIANHRTTTEFLFYLLSNFDFKNFTSG
ECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
SIIPHIYFKDYKEKTIFLPPLNEQIAIANILSDLDNEIASLKNKKRQFENIKKALNHDLM
CCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKIRVLKK
HHHHHHCCC
>Mature Secondary Structure
MLPLNWQRVRLGDIGKPCMCKRVMKHQTTRYGEIPFYKIGTFGNTADAFISKKLFLEYKT
CCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHEEEHH
KYSFPKKGDILISASGTIGRAVIYDGKPAYFQDSNIVWIDNDETLVKNDFLFYAYSNVKW
CCCCCCCCCEEEEECCCCCEEEEECCCCCEEECCEEEEECCCCEEEECCEEEEEEECEEE
NTEHTTILRLYNDNFRNTLIPLPPLNEQIAIANILSALDHYLYALDALILKKESVKKALS
CCCCEEEEEEECCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FELLSQRKRLKGFNQAWQRVRLGDIANYLTSNLSVEQITQQGKIKVYDVNNFIGYTDTTF
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEECCCCCCCCCCEE
ISDKPYISIVKDGSVGRVRILPPKTNILSTMGALIANHRTTTEFLFYLLSNFDFKNFTSG
ECCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
SIIPHIYFKDYKEKTIFLPPLNEQIAIANILSDLDNEIASLKNKKRQFENIKKALNHDLM
CCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKIRVLKK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]