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The map label for this gene is tyrA [H]

Identifier: 188528170

GI number: 188528170

Start: 1389601

End: 1390428

Strand: Direct

Name: tyrA [H]

Synonym: HPSH_07145

Alternate gene names: 188528170

Gene position: 1389601-1390428 (Clockwise)

Preceding gene: 188528169

Following gene: 188528173

Centisome position: 86.39

GC content: 42.03

Gene sequence:

>828_bases
ATGAAAGCAGGCATTATTGGTTTAGGGCTTATGGGGGGGAGTTTGGGGCTGGCCTTGCAAGAATGGGGGCGTTTTAAAAG
CGTTACAGGCTATGATCATAACGCTTTGCATGCTAAATTAGCCTTGACTTTGGGGCTTGTAGATGAATGCGTGGAATTTG
AAAAGATTTTAGAATGCGATGTGATTTTTTTGGCCATTCCAGTTGAGGGCATCATTGCATGTTTGAAAAAAATGACTCCC
ATTAAAAAAAGCGCAACGATTATTGATTTAGGGGGCGCTAAAGCGCAAATCATTCACAATATCCCTAAAAGCATTCGTAA
GAATTTCATCGCCGCGCACCCCATGTGCGGGACAGAGTTTTATGGCCCTAAAGCGAGCGTTAAGGGGCTGTATGAAAACG
CCCTTGTGATATTGTGCGATTTAGAAGATTCAGGGACTGAGCAAGTAGAGATCGCTAAAGAAATCTTTTTAGGCATTAAA
GCGCGCTTGATTAAAATGAAATCCAATGAGCATGACACCCATGTGGCTTATATCAGCCATTTACCCCATGTTTTGAGCTA
CGCTCTAGCCAATAGCGTTTTAAAGCAAAACGACCCAGAGATGATTTTATCCTTAGCGGGTGGGGGTTTTAGGGATATGA
GCCGTTTGTCTAAAAGCTCGCCTTTAATGTGGAAAGATATTTTCAAACAAAACCGAGACAATGTCTTAGAAGCGATTAAA
AAATGCGAAAAAGAAATCGCGCAAGCTAAGGCTTGGATAGAAAATAACGATTATGAAAGCCTTGCAGAATGGATGGCGCA
AGCGAACAAACTCCAGGAATTCATGTAA

Upstream 100 bases:

>100_bases
ATTTAGATGAAATCCCTGCTGAAGTGCGAGAGAATTTAAACATCGTTGCGGTGAAAAACATCGCTGAAGTGCTAGAAAAA
ACTTTGCTTTAAAATTTGGC

Downstream 100 bases:

>100_bases
AGTAAAATGATGCAGAATAATTTAAAATTTACATATCGTTGTTTTTAGAGTTGCTAGAAACAGAATGGGGTGTTTTTGGA
TTGTCTTTATTGGTTATAAG

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: PDH [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLKKMTP
IKKSATIIDLGGAKAQIIHNIPKSIRKNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGTEQVEIAKEIFLGIK
ARLIKMKSNEHDTHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVLEAIK
KCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM

Sequences:

>Translated_275_residues
MKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLKKMTP
IKKSATIIDLGGAKAQIIHNIPKSIRKNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGTEQVEIAKEIFLGIK
ARLIKMKSNEHDTHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVLEAIK
KCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
>Mature_275_residues
MKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECDVIFLAIPVEGIIACLKKMTP
IKKSATIIDLGGAKAQIIHNIPKSIRKNFIAAHPMCGTEFYGPKASVKGLYENALVILCDLEDSGTEQVEIAKEIFLGIK
ARLIKMKSNEHDTHVAYISHLPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVLEAIK
KCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM

Specific function: Tyrosine biosynthesis [C]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: 500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.12 [H]

Molecular weight: Translated: 30429; Mature: 30429

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECD
CCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VIFLAIPVEGIIACLKKMTPIKKSATIIDLGGAKAQIIHNIPKSIRKNFIAAHPMCGTEF
EEEEEECHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
YGPKASVKGLYENALVILCDLEDSGTEQVEIAKEIFLGIKARLIKMKSNEHDTHVAYISH
CCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVLEAIK
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
KCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAGIIGLGLMGGSLGLALQEWGRFKSVTGYDHNALHAKLALTLGLVDECVEFEKILECD
CCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
VIFLAIPVEGIIACLKKMTPIKKSATIIDLGGAKAQIIHNIPKSIRKNFIAAHPMCGTEF
EEEEEECHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
YGPKASVKGLYENALVILCDLEDSGTEQVEIAKEIFLGIKARLIKMKSNEHDTHVAYISH
CCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPHVLSYALANSVLKQNDPEMILSLAGGGFRDMSRLSKSSPLMWKDIFKQNRDNVLEAIK
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHH
KCEKEIAQAKAWIENNDYESLAEWMAQANKLQEFM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA