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The map label for this gene is gapB [H]

Identifier: 188528134

GI number: 188528134

Start: 1350904

End: 1351896

Strand: Reverse

Name: gapB [H]

Synonym: HPSH_06965

Alternate gene names: 188528134

Gene position: 1351896-1350904 (Counterclockwise)

Preceding gene: 188528135

Following gene: 188528133

Centisome position: 84.04

GC content: 42.4

Gene sequence:

>993_bases
ATGCCAATTAGAATCGCTATCAATGGGACTGGGCGCATCGGTTTGTGCACTATAAGAGTCGCCAGTCAAAGAAAAGATGT
AGAAATTGCCGCTATCAATTCTACCGCTGAAACAGAAACTCTTTTGCATTTGATCCGCCATGACAGCGTGCATGGGCATT
TTGAAGCCAAATTAAACGCTGATAGAACCCTAAATATCGGGCATAGTAAAAACATTTTAGTGTTGAGCGAGCGAGACATT
AACAAGCTTGATTTTTCTGTCGCTAACGCAGAAATCATCATAGAATGCACCGGGAAATTCAATTCCCTAGAAGCTTCAAG
CGCTCATCTTAAAAACAGCGTGAAAAAAGTCATCATCTCCGCTCCCGCGCAAAATACGCCAACCTTTGTCTATGGGGTGA
ATCACAAAAATTACCATAACGAAAGCGTGATTTCTAACGCTTCTTGCACGACTAACGCTACCACTCCTTTATTAAAAATC
TTAGATGAAGCCTTTAAAGTAGAAAACGCGCTTTTAACCACCATTCACAGCTACACTAACGATCAAAACCTTTTAGACAC
CAAGCACAAAGACATCCGCCGCGCTAGAGCAGCCAGCCTTAACCTCATCCCTACAAGCACCGGCGTGAGCAAAGCCATTT
CGCTAGTCTTACCGCATTTAGGCCCTAAGATCACAGGCCTTGCTATTAGAGTGCCTACCCCTAATGTGAGCTTAGTGGAT
CTGTCTTTAAGCTTTAAAAAATCCGTGAGTAAAGCGAGCGTTCAGCATGCGCTTAAAGACGCTTGCAAGCATGCCTTTAA
AGGGGTTGTGAGTATTGATGAAGAAAGGCTTGTTTCAAGCGATTTTATTTCTTCGCCTTTTAGCGCGATTGTGATTGATG
ATCAAATCATGACAATAGGCGAAAAAAATGCTAAAGTATTGGCATGGTATGATAATGAAATGGGTTATAGCGAGCGCTTG
ATAGACATGGCGCAATATATAGCGCAAAATTAA

Upstream 100 bases:

>100_bases
TTTAGTTTATGATTGATGCTTAATGAGACAGAACCCCTTAAGAATACCTTTATTTAAGAGCGTTTGTGATAAAATGGTGA
TTTTTAAATAAAGGGAAAAC

Downstream 100 bases:

>100_bases
AAGAAAGGATTTTTCATGTTAGCTAAAATGTCGTTTATGCAAAACGTTAAAAACATTCAAGAAGTGGAAGTGGGTCATAA
AAGGGTGCTTATTAGAGTGG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPIRIAINGTGRIGLCTIRVASQRKDVEIAAINSTAETETLLHLIRHDSVHGHFEAKLNADRTLNIGHSKNILVLSERDI
NKLDFSVANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNATTPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAASLNLIPTSTGVSKAISLVLPHLGPKITGLAIRVPTPNVSLVD
LSLSFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN

Sequences:

>Translated_330_residues
MPIRIAINGTGRIGLCTIRVASQRKDVEIAAINSTAETETLLHLIRHDSVHGHFEAKLNADRTLNIGHSKNILVLSERDI
NKLDFSVANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNATTPLLKI
LDEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAASLNLIPTSTGVSKAISLVLPHLGPKITGLAIRVPTPNVSLVD
LSLSFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERL
IDMAQYIAQN
>Mature_329_residues
PIRIAINGTGRIGLCTIRVASQRKDVEIAAINSTAETETLLHLIRHDSVHGHFEAKLNADRTLNIGHSKNILVLSERDIN
KLDFSVANAEIIIECTGKFNSLEASSAHLKNSVKKVIISAPAQNTPTFVYGVNHKNYHNESVISNASCTTNATTPLLKIL
DEAFKVENALLTTIHSYTNDQNLLDTKHKDIRRARAASLNLIPTSTGVSKAISLVLPHLGPKITGLAIRVPTPNVSLVDL
SLSFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIGEKNAKVLAWYDNEMGYSERLI
DMAQYIAQN

Specific function: More active in anabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=37.6899696048632, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=35.1681957186544, Blast_Score=232, Evalue=4e-61,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=37.7643504531722, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1789295, Length=328, Percent_Identity=38.4146341463415, Blast_Score=241, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=38.7387387387387, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=38.4384384384384, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=38.4384384384384, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=38.4384384384384, Blast_Score=249, Evalue=1e-66,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=40, Blast_Score=266, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=39.6969696969697, Blast_Score=260, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=39.6969696969697, Blast_Score=259, Evalue=4e-70,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=39.6923076923077, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=38.6503067484663, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=38.6503067484663, Blast_Score=254, Evalue=4e-68,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=38.0368098159509, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=38.0368098159509, Blast_Score=254, Evalue=8e-68,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.59 [H]

Molecular weight: Translated: 36087; Mature: 35955

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIRIAINGTGRIGLCTIRVASQRKDVEIAAINSTAETETLLHLIRHDSVHGHFEAKLNA
CEEEEEEECCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DRTLNIGHSKNILVLSERDINKLDFSVANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CEEEECCCCCCEEEEECCCCCHHEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHEEEEE
APAQNTPTFVYGVNHKNYHNESVISNASCTTNATTPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAASLNLIPTSTGVSKAISLVLPHLGPKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEE
LSLSFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIRIAINGTGRIGLCTIRVASQRKDVEIAAINSTAETETLLHLIRHDSVHGHFEAKLNA
EEEEEEECCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECC
DRTLNIGHSKNILVLSERDINKLDFSVANAEIIIECTGKFNSLEASSAHLKNSVKKVIIS
CEEEECCCCCCEEEEECCCCCHHEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHEEEEE
APAQNTPTFVYGVNHKNYHNESVISNASCTTNATTPLLKILDEAFKVENALLTTIHSYTN
CCCCCCCEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DQNLLDTKHKDIRRARAASLNLIPTSTGVSKAISLVLPHLGPKITGLAIRVPTPNVSLVD
CCCHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEE
LSLSFKKSVSKASVQHALKDACKHAFKGVVSIDEERLVSSDFISSPFSAIVIDDQIMTIG
EEEHHHHHHHHHHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCCCCEEEEECCEEEEEC
EKNAKVLAWYDNEMGYSERLIDMAQYIAQN
CCCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10799476 [H]