BacMap

Definition	Helicobacter pylori Shi470, complete genome.
Accession	NC_010698
Length	1,608,548

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The map label for this gene is dnaJ [H]

Identifier: 188528120

GI number: 188528120

Start: 1339132

End: 1340241

Strand: Reverse

Name: dnaJ [H]

Synonym: HPSH_06885

Alternate gene names: 188528120

Gene position: 1340241-1339132 (Counterclockwise)

Preceding gene: 188528124

Following gene: 188528119

Centisome position: 83.32

GC content: 41.35

Gene sequence:

>1110_bases
GTGGAATTGAGTTATTATGAAATTTTAGAAGTGGAAAAACACAGCAACCAAGAGACCATTAAAAAGTCTTACAGAAAGTT
GGCTTTAAAATACCACCCAGACAGAAACGCCGGCGATAAAGAAGCCGAAGAAAAGTTCAAGCTCATCAATGAAGCCTATG
GGGTGTTAAGCGATGAAAAGAAACGGGCCTTATACGATAGGTATGGTAAAAAAGGCTTAAACCAAGCCGGTGCGAGCCAG
AGCGATTTTTCTGATTTTTTTGAAGATTTAGGCTCGTTTTTTGAAGACGCTTTTGGCTTTGGCGCTAGAGGGAGTAAAAG
GCAAAAAAGCTCTATCGCACCGGATTATTTGCAAATTATTGAATTGAGTTTTAAAGAAGCGGTTTTTGGCTGTAAGAAAA
CCATTAAAGTCCAATACCAGAGCGTTTGTGAAAGTTGCGATGGCACGGGCGCTAAGGATAAAGCCCTAGAAACTTGCAAG
CAATGCAACGGGCAGGGGCAAGTGTTTATGCGTCAAGGTTTTATGAGTTTTGCGCAAACTTGCGGGGCGTGTAAAGGCAA
GGGTAAAACCATTAAGACCCCATGCCAAGCGTGTAAGGGTAAAACCTACATCCTTAAAGATGAAGAAATTGATGCGATGA
TCCCTGAGGGCATTGATGATCAAAACCGCATGGTGCTTAAAAATAAAGGCAATGAATACGAGAAGGGAAAAAGAGGGGAT
TTGTATTTAGAAGCGCGAGTCAAAGAAGATGAGCATTTCAAGCGCGAAGGCTGTGATTTGTTCATTGAAGCACCGGTATT
TTTCACCACTATCGCTTTAGGGCATACGATTAAAGTGCCGTCTTTAAAAGGGGACGAACTGGAATTAAAAATCCCTAGAA
ACGCCAAAGACAGGCAGACTTTTGCGTTTAGAAACGAGGGCGTGAAACACCCGGAAAGCTCTTATAGAGGGAGTTTGATC
GTGGAATTGCAAGTGATTTACCCTAAAAGTTTGAATAAAGAACAGCAAGAGTTATTGGAAAAGTTGCATGCGAGTTTTGG
CTATGAGAGCGAGCCGCATAAAAGCGTTTTAGAAACTTGTATTTCTAAAATTAAAGACTGGTTTAAATGA

Upstream 100 bases:

>100_bases
TCATCGTGTTATTTTATCTAAGTTTTGGCATGCATGAAAACACGCAAACCCACCGCTTTTAAGATAAAATAAGCGTTTTG
ATGCCATTTTTGGAGCGATC

Downstream 100 bases:

>100_bases
AAGGTTGTTGATGCATGATTTTCTAAAAGCCTTTAAAGACGCTTTCCCTCATACCATTTCTATCTTTTTAGGGTATTTGC
TTATGGGAATGACTTTTGGG

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQ
SDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQIIELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCK
QCNGQGQVFMRQGFMSFAQTCGACKGKGKTIKTPCQACKGKTYILKDEEIDAMIPEGIDDQNRMVLKNKGNEYEKGKRGD
LYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNAKDRQTFAFRNEGVKHPESSYRGSLI
VELQVIYPKSLNKEQQELLEKLHASFGYESEPHKSVLETCISKIKDWFK

Sequences:

>Translated_369_residues
MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQ
SDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQIIELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCK
QCNGQGQVFMRQGFMSFAQTCGACKGKGKTIKTPCQACKGKTYILKDEEIDAMIPEGIDDQNRMVLKNKGNEYEKGKRGD
LYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNAKDRQTFAFRNEGVKHPESSYRGSLI
VELQVIYPKSLNKEQQELLEKLHASFGYESEPHKSVLETCISKIKDWFK
>Mature_369_residues
MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEKKRALYDRYGKKGLNQAGASQ
SDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQIIELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCK
QCNGQGQVFMRQGFMSFAQTCGACKGKGKTIKTPCQACKGKTYILKDEEIDAMIPEGIDDQNRMVLKNKGNEYEKGKRGD
LYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNAKDRQTFAFRNEGVKHPESSYRGSLI
VELQVIYPKSLNKEQQELLEKLHASFGYESEPHKSVLETCISKIKDWFK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=341, Percent_Identity=30.2052785923754, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI205360840, Length=341, Percent_Identity=30.2052785923754, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI194328758, Length=353, Percent_Identity=30.8781869688385, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI194328760, Length=353, Percent_Identity=30.8781869688385, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4504511, Length=355, Percent_Identity=30.1408450704225, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI5031741, Length=352, Percent_Identity=27.8409090909091, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI201862587, Length=358, Percent_Identity=27.0949720670391, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI56549115, Length=358, Percent_Identity=27.0949720670391, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI201862518, Length=358, Percent_Identity=27.0949720670391, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI6631085, Length=393, Percent_Identity=25.6997455470738, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI194328762, Length=319, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI7706495, Length=346, Percent_Identity=27.4566473988439, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5453690, Length=363, Percent_Identity=25.6198347107438, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI47777312, Length=96, Percent_Identity=51.0416666666667, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI27151736, Length=108, Percent_Identity=45.3703703703704, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI88501736, Length=79, Percent_Identity=54.4303797468354, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI23503241, Length=99, Percent_Identity=50.5050505050505, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI17388799, Length=87, Percent_Identity=58.6206896551724, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4885495, Length=87, Percent_Identity=58.6206896551724, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI21553335, Length=81, Percent_Identity=50.6172839506173, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI45504382, Length=70, Percent_Identity=54.2857142857143, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI39204547, Length=185, Percent_Identity=31.3513513513514, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI29126218, Length=70, Percent_Identity=55.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27735107, Length=88, Percent_Identity=43.1818181818182, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI9558755, Length=101, Percent_Identity=43.5643564356436, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI217035105, Length=76, Percent_Identity=43.421052631579, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI68077168, Length=91, Percent_Identity=45.0549450549451, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI68077166, Length=91, Percent_Identity=45.0549450549451, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI194306642, Length=86, Percent_Identity=46.5116279069767, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI194306640, Length=86, Percent_Identity=46.5116279069767, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI24308127, Length=94, Percent_Identity=41.4893617021277, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI56687498, Length=115, Percent_Identity=37.3913043478261, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI22749377, Length=66, Percent_Identity=51.5151515151515, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI72534740, Length=66, Percent_Identity=51.5151515151515, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786197, Length=359, Percent_Identity=42.0612813370474, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1787235, Length=351, Percent_Identity=26.4957264957265, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17553098, Length=358, Percent_Identity=30.7262569832402, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17553096, Length=358, Percent_Identity=30.7262569832402, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17507263, Length=351, Percent_Identity=29.6296296296296, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17534355, Length=384, Percent_Identity=25, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17563890, Length=362, Percent_Identity=26.5193370165746, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI212645553, Length=334, Percent_Identity=26.3473053892216, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115532378, Length=96, Percent_Identity=41.6666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554644, Length=85, Percent_Identity=48.2352941176471, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17554874, Length=91, Percent_Identity=42.8571428571429, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568643, Length=72, Percent_Identity=51.3888888888889, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI86563276, Length=122, Percent_Identity=40.9836065573771, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=374, Percent_Identity=29.9465240641711, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323870, Length=358, Percent_Identity=28.4916201117318, Blast_Score=135, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6321094, Length=386, Percent_Identity=29.2746113989637, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323119, Length=269, Percent_Identity=30.1115241635688, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324103, Length=87, Percent_Identity=45.9770114942529, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323813, Length=99, Percent_Identity=44.4444444444444, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322194, Length=106, Percent_Identity=39.622641509434, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324321, Length=68, Percent_Identity=50, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320888, Length=99, Percent_Identity=38.3838383838384, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324252, Length=66, Percent_Identity=48.4848484848485, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129487, Length=265, Percent_Identity=34.3396226415094, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24584014, Length=265, Percent_Identity=34.3396226415094, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24646562, Length=343, Percent_Identity=30.9037900874636, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24646560, Length=343, Percent_Identity=30.9037900874636, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24646558, Length=343, Percent_Identity=30.9037900874636, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24646556, Length=343, Percent_Identity=30.9037900874636, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI21357547, Length=343, Percent_Identity=30.9037900874636, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI45552813, Length=376, Percent_Identity=29.2553191489362, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI45552811, Length=374, Percent_Identity=28.8770053475936, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI45549272, Length=374, Percent_Identity=28.8770053475936, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574949, Length=347, Percent_Identity=26.2247838616715, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24658562, Length=390, Percent_Identity=25.8974358974359, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658555, Length=390, Percent_Identity=25.8974358974359, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI85726398, Length=371, Percent_Identity=26.4150943396226, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18858081, Length=357, Percent_Identity=26.6106442577031, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654066, Length=101, Percent_Identity=48.5148514851485, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654070, Length=101, Percent_Identity=48.5148514851485, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654068, Length=101, Percent_Identity=48.5148514851485, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654072, Length=101, Percent_Identity=48.5148514851485, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737735, Length=70, Percent_Identity=54.2857142857143, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574723, Length=70, Percent_Identity=54.2857142857143, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24668523, Length=70, Percent_Identity=54.2857142857143, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19920464, Length=341, Percent_Identity=24.0469208211144, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24762799, Length=91, Percent_Identity=41.7582417582418, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24651439, Length=72, Percent_Identity=44.4444444444444, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668492, Length=73, Percent_Identity=45.2054794520548, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24651436, Length=72, Percent_Identity=44.4444444444444, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358311, Length=72, Percent_Identity=44.4444444444444, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161077138, Length=65, Percent_Identity=49.2307692307692, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 41972; Mature: 41972

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCHH
KRALYDRYGKKGLNQAGASQSDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQII
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHH
ELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCKQCNGQGQVFMRQGFMSFAQT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
CGACKGKGKTIKTPCQACKGKTYILKDEEIDAMIPEGIDDQNRMVLKNKGNEYEKGKRGD
HHCCCCCCCCCCCHHHHHCCCEEEEECCCCCHHCCCCCCCCCCEEEECCCCCCCCCCCCC
LYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNAKDRQT
EEEEEECCCHHHHHHCCCCEEEECHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCHHHH
FAFRNEGVKHPESSYRGSLIVELQVIYPKSLNKEQQELLEKLHASFGYESEPHKSVLETC
HHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ISKIKDWFK
HHHHHHHCC
>Mature Secondary Structure
MELSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKEAEEKFKLINEAYGVLSDEK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCHH
KRALYDRYGKKGLNQAGASQSDFSDFFEDLGSFFEDAFGFGARGSKRQKSSIAPDYLQII
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHH
ELSFKEAVFGCKKTIKVQYQSVCESCDGTGAKDKALETCKQCNGQGQVFMRQGFMSFAQT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHH
CGACKGKGKTIKTPCQACKGKTYILKDEEIDAMIPEGIDDQNRMVLKNKGNEYEKGKRGD
HHCCCCCCCCCCCHHHHHCCCEEEEECCCCCHHCCCCCCCCCCEEEECCCCCCCCCCCCC
LYLEARVKEDEHFKREGCDLFIEAPVFFTTIALGHTIKVPSLKGDELELKIPRNAKDRQT
EEEEEECCCHHHHHHCCCCEEEECHHHHHHHHHCCEEECCCCCCCCEEEECCCCCCHHHH
FAFRNEGVKHPESSYRGSLIVELQVIYPKSLNKEQQELLEKLHASFGYESEPHKSVLETC
HHHHHCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ISKIKDWFK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]