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The map label for this gene is slyD [H]

Identifier: 188527907

GI number: 188527907

Start: 1140988

End: 1141536

Strand: Reverse

Name: slyD [H]

Synonym: HPSH_05790

Alternate gene names: 188527907

Gene position: 1141536-1140988 (Counterclockwise)

Preceding gene: 188527908

Following gene: 188527906

Centisome position: 70.97

GC content: 44.26

Gene sequence:

>549_bases
ATGCAAAACCATGATTTAGAGTCGGTCAAACAAGCCGCTTTGATTGAATATGAAGTGAGGGAGCAGGGGTCTAGCGTTGT
GCTAGACAGTAATATTTCTAAAGAGCCTTTAGAGTTTATTATAGGCGCTAATCAAATCATAGCGGGGTTGGAAAAAGCGG
TATTAAAGGCTCAAATTGGCGAGTGGGAAGAGGTTGTTATCGCTCCAGAAGAAGCTTATGGGGTTTATGAAAGCAGCTAT
TTGCAAGAAGTCCCTAGAGATCAATTTGAAGGCATTGAATTGGAAAAAGGCATGAGCGTTTTTGGGCAAACTGAAGACCA
TCAAACCATTCAAGCCACTATCAAAGATTTTAGCAACACGCATGTGATGGTGGATTATAACCACCCGTTAGCCGGGAAAA
CTTTAGCGTTTCGTTTCAAGGTTTTAGGCTTTAGGGAAGTGAACGAAGAAGAAATTTTAGCTTCACACCATGGCGGTGGG
ACAGGTTGCTGTGGCGGTCATGGCGGAAATAAAGGTGGGGGCTGTGGTTGCTCATGCTCGCATGGGTAG

Upstream 100 bases:

>100_bases
AACTATTATAAATTTTTAAACACTTTGCAACACTTGTATCCTTCAAGCGAACAAGCTAAAATGGCAAAAAAAATCTTAGA
AAACAAGGAGAAACACCATC

Downstream 100 bases:

>100_bases
TAGGGTATAAGAGCATTTAAAAGGCAAGGTCATGAATAGTTCTAATCTCAAAAATTGGCTGTTCCCTACCATTTGCTTTT
TTTTGTTTTGTTATATTTTA

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQNHDLESVKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDHQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVNEEEILASHHGGG
TGCCGGHGGNKGGGCGCSCSHG

Sequences:

>Translated_182_residues
MQNHDLESVKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDHQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVNEEEILASHHGGG
TGCCGGHGGNKGGGCGCSCSHG
>Mature_182_residues
MQNHDLESVKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSY
LQEVPRDQFEGIELEKGMSVFGQTEDHQTIQATIKDFSNTHVMVDYNHPLAGKTLAFRFKVLGFREVNEEEILASHHGGG
TGCCGGHGGNKGGGCGCSCSHG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=139, Percent_Identity=35.9712230215827, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19755; Mature: 19755

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHDLESVKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDHQTIQATIKDFSNT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHHCCCCCHHHHHHHHHHCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVNEEEILASHHGGGTGCCGGHGGNKGGGCGCSCS
EEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
HG
CC
>Mature Secondary Structure
MQNHDLESVKQAALIEYEVREQGSSVVLDSNISKEPLEFIIGANQIIAGLEKAVLKAQIG
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHCC
EWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDHQTIQATIKDFSNT
CCEEEEECCHHHHCCHHHHHHHHCCHHHHCCEEHHCCCHHHCCCCCHHHHHHHHHHCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVNEEEILASHHGGGTGCCGGHGGNKGGGCGCSCS
EEEEEECCCCCCCEEEEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
HG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]