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The map label for this gene is exoB [H]

Identifier: 188527874

GI number: 188527874

Start: 1107765

End: 1108799

Strand: Reverse

Name: exoB [H]

Synonym: HPSH_05615

Alternate gene names: 188527874

Gene position: 1108799-1107765 (Counterclockwise)

Preceding gene: 188527877

Following gene: 188527863

Centisome position: 68.93

GC content: 40.1

Gene sequence:

>1035_bases
ATGGCATTATTATTCACAGGGGCGTGCGGGTATATAGGCTCGCATACCGCAAGGGCGTTTTTAGAAAAAACTAAAGAAAA
CATCGTTGTTGTAGATGATCTCAGCACCGGTTTTTTAGAACATCTCAAAGCGTTAGAGCATTATTACCCTAATAGGGTTG
TGTTTGTTCAAGCCAATTTGAATGAAACGCAAAAATTAGATGCATTTTTGAATAAGCAGCAGCTAAAAGATCCCATTGAA
GCTATCTTGCACTTTGGGGCTAAAATCTCAGTAGAAGAATCCATGCGCTTGCCTTTAGAATACTACACCAACAACACGCT
CAACACTTTAGAGCTTGTCAAACTTTGTTTAAAACATGCGATCAAGCGTTTTATTTTTTCTTCTACGGCCGTGGTTTATG
GCGAGTCTGATTCTAGCTTGAATGAAGAAAGCCCCTTAAACCCCATTAATCCTTATGGAGCGTCTAAAATGATGAGCGAA
AGGATTTTGTTGGACACTTCTAAAATAGCGGATTTTAATTGCGTTATTTTGCGCTATTTCAATGTGGCTGGAGCATGCAT
GCACAATGATTATGCCACCCCTTACACGCTGGGCCAGCGCACGCTCAACGCCACGCATTTAATCAAAATCGCATGCGAAT
GCGCGGTGGGGAAAAGGAAAAAAATGGGGATTTTTGGCACTAACTACCCCACAAGAGATGGCACTTGCATTAGGGATTAT
ATCCATGTAGATGATTTGGCTAACGCGCATTTAGCGAGCTATCAAACCCTTTTAGAAAAAAATAAGAGCGAGATCTATAA
TGTCGGCTACAATCAAGGTCATAGCGTGAAAGAAGTGATAGAAAAGGTTAAAGAAATCTCAAACAACGATTTTTTAGTGG
AAATTTTAGACAAACGACAGGGCGATCCAGCAAGCCTTATTGCCAATAACGCTAAAATCTTACAAAACACCTCTTTCAAA
CCCCTTTATAACAACCTAGACACCATTATCAAAAGCGCTCTAGATTGGGAAGAACACCTTTTGAGATTTCAATAA

Upstream 100 bases:

>100_bases
AGATGAAATTATAGGTTAAACTTTCTTAAAAAATCCTTAAACAATAAATGGGATTAAGATGTTATAATACTCGTTATTTT
TTCATTTCAAAAGGGGTTTT

Downstream 100 bases:

>100_bases
TACACCCTGTGCAAATACAAGCCATTAGCCATTATGGGCGTTCTTATAGTGGCTTTGATGTTGTGGATTTGCGCTTGAAT
TTCAGCGAGCGTGATTTTTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MALLFTGACGYIGSHTARAFLEKTKENIVVVDDLSTGFLEHLKALEHYYPNRVVFVQANLNETQKLDAFLNKQQLKDPIE
AILHFGAKISVEESMRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAVVYGESDSSLNEESPLNPINPYGASKMMSE
RILLDTSKIADFNCVILRYFNVAGACMHNDYATPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVIEKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFK
PLYNNLDTIIKSALDWEEHLLRFQ

Sequences:

>Translated_344_residues
MALLFTGACGYIGSHTARAFLEKTKENIVVVDDLSTGFLEHLKALEHYYPNRVVFVQANLNETQKLDAFLNKQQLKDPIE
AILHFGAKISVEESMRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAVVYGESDSSLNEESPLNPINPYGASKMMSE
RILLDTSKIADFNCVILRYFNVAGACMHNDYATPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVIEKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFK
PLYNNLDTIIKSALDWEEHLLRFQ
>Mature_343_residues
ALLFTGACGYIGSHTARAFLEKTKENIVVVDDLSTGFLEHLKALEHYYPNRVVFVQANLNETQKLDAFLNKQQLKDPIEA
ILHFGAKISVEESMRLPLEYYTNNTLNTLELVKLCLKHAIKRFIFSSTAVVYGESDSSLNEESPLNPINPYGASKMMSER
ILLDTSKIADFNCVILRYFNVAGACMHNDYATPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDYI
HVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVIEKVKEISNNDFLVEILDKRQGDPASLIANNAKILQNTSFKP
LYNNLDTIIKSALDWEEHLLRFQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=351, Percent_Identity=31.3390313390313, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI56118217, Length=351, Percent_Identity=31.3390313390313, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI189083684, Length=351, Percent_Identity=31.3390313390313, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI7657641, Length=308, Percent_Identity=26.6233766233766, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=23.7942122186495, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=32.8445747800587, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1788353, Length=370, Percent_Identity=24.8648648648649, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790049, Length=284, Percent_Identity=26.4084507042254, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994969, Length=297, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=318, Percent_Identity=34.9056603773585, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71982038, Length=321, Percent_Identity=33.6448598130841, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17568069, Length=276, Percent_Identity=27.8985507246377, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=318, Percent_Identity=35.8490566037736, Blast_Score=177, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19923002, Length=351, Percent_Identity=29.6296296296296, Blast_Score=154, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38882; Mature: 38751

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLFTGACGYIGSHTARAFLEKTKENIVVVDDLSTGFLEHLKALEHYYPNRVVFVQANL
CEEEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECC
NETQKLDAFLNKQQLKDPIEAILHFGAKISVEESMRLPLEYYTNNTLNTLELVKLCLKHA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
IKRFIFSSTAVVYGESDSSLNEESPLNPINPYGASKMMSERILLDTSKIADFNCVILRYF
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHHHCCCCHHHHHHHH
NVAGACMHNDYATPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
HHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHH
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVIEKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTSFKPLYNNLDTIIKSALDWEEHLLRFQ
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCC
>Mature Secondary Structure 
ALLFTGACGYIGSHTARAFLEKTKENIVVVDDLSTGFLEHLKALEHYYPNRVVFVQANL
EEEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECC
NETQKLDAFLNKQQLKDPIEAILHFGAKISVEESMRLPLEYYTNNTLNTLELVKLCLKHA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHCCCCCCHHHHHHHHHHHH
IKRFIFSSTAVVYGESDSSLNEESPLNPINPYGASKMMSERILLDTSKIADFNCVILRYF
HHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEHHHCCCCHHHHHHHH
NVAGACMHNDYATPYTLGQRTLNATHLIKIACECAVGKRKKMGIFGTNYPTRDGTCIRDY
HHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHH
IHVDDLANAHLASYQTLLEKNKSEIYNVGYNQGHSVKEVIEKVKEISNNDFLVEILDKRQ
HHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCC
GDPASLIANNAKILQNTSFKPLYNNLDTIIKSALDWEEHLLRFQ
CCCHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]