Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 188527750

GI number: 188527750

Start: 971540

End: 972472

Strand: Direct

Name: htpX [H]

Synonym: HPSH_04885

Alternate gene names: 188527750

Gene position: 971540-972472 (Clockwise)

Preceding gene: 188527749

Following gene: 188527751

Centisome position: 60.4

GC content: 37.62

Gene sequence:

>933_bases
ATGACGAATTTTGAAAAAATTATCGCGCAAAACAAGCTCAAAACAAACGCGGTTTTAGCGACTTATTGCGTGATTTTTGC
TTTTATTGGGTTGTTGGTGGATGTTATTAGAATTAATGCTAACGATTTAGGAACAGCTCTTTTTAAACTCATGACTTTTC
AAATTTTTCCTACGATCACCATCATTATGTTTTTAGTGGCTTTTGTCATTATTGTTGTTTGTATCCAAAATTTTAGCTCT
ATCATGTTAAGCGGTGATGAATACAAGCTTATTGACAAAAGCAAGGTTTTAAGCTCTAAAGAAAACCAAATCCATCGCCT
TTTGTTAGAGCTTTTAGAAGAGGCTAAGCTTCATTTTGAGCCTAAGCTTTATATCATTAAAGCCCCTTACATGAACGCTT
TTGCGAGCGGGTGGAATGAATCTAATTCCCTTATCGCTCTTACAAGCGCTTTAATAGAGAGATTAGATAGAGATGAATTA
AAAGCTGTGATCGCTCATGAGCTCAGCCACATCAGGCACAATGACATTCGCTTGACCATGTGTGTGGGGATTTTAAGCAA
TATCATGCTGTTAGTGGCTAATTTTAGCGTGTATTTTTTCATGGGGAATCGCAAGAATAGCGGGGCGAATTTAGCCCGAA
TGATTTTATTAGTTTTACAGATCATTTTGCCTTTTTTAACGCTCCTTTTACAAATGTATTTGAGTCGCACACGAGAATAC
ATGGCTGATAGCGGGGCGGCGTTTTTAATGCATGACAATAAGCCTATGATTAGAGCCTTACAAAAAATTTCTAACGACTA
TGCGAACAACGATTACAAGGGTGTAGATCAGAACTCCACTCGATCGGCAGCTTATCTTTTTAGCGCTGAAATGTTTAGCA
CCCACCCTAGCATTAAAAATCGTATCCAATCTTTATCAAGGCGCGTCATTTAA

Upstream 100 bases:

>100_bases
GTGAAAGAAAAAGCGCAATTTGAATTGGGATTTTACTTGCCTAAAGGGAGTTATGCGAGCGCGTTGCTCAAAGAAATCAA
GCATGAGAAAGGAGAAAATA

Downstream 100 bases:

>100_bases
ATGGAAAATTTTTTCAACCAGTTTTTTGAAAATATCGGCGAAGATAAAAACAGAGAAGGTTTGAAAGAGACGCCTAAAAG
GGTTCAAGAATTATGGAAAT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTNFEKIIAQNKLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTITIIMFLVAFVIIVVCIQNFSS
IMLSGDEYKLIDKSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDEL
KAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREY
MADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKNRIQSLSRRVI

Sequences:

>Translated_310_residues
MTNFEKIIAQNKLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTITIIMFLVAFVIIVVCIQNFSS
IMLSGDEYKLIDKSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDEL
KAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREY
MADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKNRIQSLSRRVI
>Mature_309_residues
TNFEKIIAQNKLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTITIIMFLVAFVIIVVCIQNFSSI
MLSGDEYKLIDKSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDELK
AVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREYM
ADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKNRIQSLSRRVI

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=195, Percent_Identity=31.7948717948718, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 35258; Mature: 35127

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFEKIIAQNKLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTIT
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IIMFLVAFVIIVVCIQNFSSIMLSGDEYKLIDKSKVLSSKENQIHRLLLELLEEAKLHFE
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
PKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTM
CEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH
CVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREY
HHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKN
HHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
RIQSLSRRVI
HHHHHHHCCC
>Mature Secondary Structure 
TNFEKIIAQNKLKTNAVLATYCVIFAFIGLLVDVIRINANDLGTALFKLMTFQIFPTIT
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IIMFLVAFVIIVVCIQNFSSIMLSGDEYKLIDKSKVLSSKENQIHRLLLELLEEAKLHFE
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
PKLYIIKAPYMNAFASGWNESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTM
CEEEEEECCHHHHHHCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHH
CVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILLVLQIILPFLTLLLQMYLSRTREY
HHHHHHHHHHHHHHCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MADSGAAFLMHDNKPMIRALQKISNDYANNDYKGVDQNSTRSAAYLFSAEMFSTHPSIKN
HHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHH
RIQSLSRRVI
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]