| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is uvrA
Identifier: 188527448
GI number: 188527448
Start: 630594
End: 633419
Strand: Direct
Name: uvrA
Synonym: HPSH_03330
Alternate gene names: 188527448
Gene position: 630594-633419 (Clockwise)
Preceding gene: 188527442
Following gene: 188527460
Centisome position: 39.2
GC content: 40.38
Gene sequence:
>2826_bases TTGCAACATAAAACCATTATGGATAAGATCATTATTCAAGGGGCTAGGGAAAATAATCTCAAAAATATTTTTTTAGAAAT CCCTAAAAACCAGTTTGTTGTTTTTACCGGATTAAGCGGTTCGGGTAAATCCACTCTGGCGTTTGACACTTTATACGCTG AAGGCCAAAGGCGCTATTTAGAGAGTTTGTCCAGCTATGCGAGGCAATTTTTAGACAAAGTGGGTAAGCCTAATGTGGAT AAAATTGAAGGCCTAACCCCTGCGATTGCTATTGATCAAAAAACCACTTCTAAAAACCCTAGATCCACTGTGGGGACGAT CACTGAGATTTATGATTATTTAAGGTTGTTGTTTGCAAGGATTGGGGAGCAATTTTGCCCCACATGTTTAGAGCCCATTA GTTCTATGAGCGCGAGCGATATTATTTCTCAAATCTGTCATTTAGAAGAAAATTCTAAAATCATTATTCTAGCCCCCATT ATTAAAGATAAAAAAGGTTCGTTTAACGATAAATTAGAGAGCTTGCGTTTAAAGGGGTATGTGAGAGCTTTTGTTGATGG GGTGATGGTGCGTTTAGATGAAGAAATCCATTTGCACAAAACCAAAAAACACACCATTGAAGCGGTGGTGGATAGAGTGG TTATCAATAGCGAAAATTCTTCACGGATCGCTAGCGCAATAGAAAAAGCCCTTAAAGAAAGCTATGGGGAATTAGAAGTG GAAATCTTGCAAGACAATGCGCCAAGCATCAGGAAGCATTACAGCGAGCATAAGGCATGCTTTAAATGCAAGATGAGTTT TGAAGAATTAGAGCCTTTGAGTTTTTCATTCAATTCGCCTAAAGGGGCGTGCGAGAGTTGTTTGGGTTTGGGGACAAAAT TCAGTTTAGACATTAGTAAGATTTTAGACCCTAACACGCCTTTAAATCAAGGAGCGATTAAAGTGATTTTTGGGTATAAC CGCAGTTATTACGCTCAAATGTTTGAAGGCTTTTGCGAATACAATGGCATTGACACCGCGCTTTGTTTTAATGAATTGAA TAAAGAGCAACAGGACGCTCTTTTGTATGGGAATGGCACTGAAATCAGCTTTCATTTCAAAAACAGCCCTTTAAAACGCC CTTGGAAAGGCATTATCCAAATCGCTTATGACATGTTTAAAGAGCAAAAGGATTTGAGCGATTACATGAGCGAAAAAACC TGTTCTTCGTGCGAGGGGCATCGTTTGAAAGCCTCAAGTTTGAGCGTCCAAGTCGCTGGCTTGAAAATGGCGGATTTTTT AACTAAGCCTATTGAAGAGGTCTATCACTTTTTTAATGATCCCACGCATTTTAGCTATCTTAACGAGCAAGAAAAAAAGA TCGCTGAACCCATTTTAAAAGAGATTTTAGAAAGGGTGTTTTTTTTATACGATGTGGGGCTAGGGTATTTGACTTTAGGG CGGGATGCGCGAACGATTAGCGGAGGGGAGAGCCAAAGGATACGAATCGCTAGTCAAATCGGGAGCGGTCTGACGGGGGT TTTGTATGTTTTAGACGAGCCTAGCATTGGCTTGCATGAAAAAGACACGCTCAAACTCATCAACACCCTTAGGAATTTAC AAAAAAAGGGGAACACGCTCATTGTCGTAGAGCATGACAAAGAGACGATTAAGCATGCGGATTTTGTTGTGGATATTGGG CCAAAGGCTGGAAGGCATGGGGGTGAAGTGGTTTTTAGCGGGAGCGTAAAAGATTTATTGCAAAACAACCATTCTACCGC TTTGTATCTCAACGGCACTAAAAAGATTGAGCGCCCTAAATTGGAACTCCCTAAAGAAAAGCATTTTTTAGAAATTAAAA ATGTCAATATCAATAACATTAAGAATTTGAGCGTTCAAATCCCTTTAAAACAATTGGTGTGCATTACTGGGGTGAGCGGG AGCGGTAAAAGCTCGCTGATTTTACAAACCCTTTTACCCACCGCTCAAACCCTTTTAAACCATGCTAAAAAAATTCAAAG CTTGAATGGGGTGGAGATTGTAGGGTTGGAGCATTTGGATAAAGTGATTTATTTAGACCAAGCCCCCATAGGAAAAACCC CACGAAGCAACCCTGCCACTTATACAGGAGTGATGGATGAAATCAGGATTTTATTTGCCGAGCAAAAAGAAGCTAAAATT TTAGGCTATAGCGCGAGCCGTTTTAGCTTTAATGTTAAAGGGGGGCGGTGCGAGAAATGCCAAGGCGATGGGGATATTAA AATAGAAATGCACTTTTTGCCTGATGTGTTGGTCCAATGCGATAGCTGTAAGGGCACTAAATACAACCCTCAGACTTTAG AAATCAAGGTGAAAGGCAAATCCATTGCCGATGTATTAAACATGAGCGTAGAAGAAGCCTATGAATTTTTTGCTAAATTC CCTAAAATCGCTGTGAAGTTAAAAACCCTTATAGATGTGGGCTTAGGCTATATCACTTTAGGGCAAAACGCTACGACTTT AAGCGGGGGGGAGGCTCAAAGGATCAAATTAGCTAAAGAATTGAGCAAAAAAGACACAGGCAAAACCCTTTATATTTTAG ATGAGCCTACCACCGGTTTGCATTTTGAAGATGTGAATCACCTTTTACAAGTTTTGCATTCTTTAGTGGCGTTAGGCAAT TCCATGATAGTGATTGAGCATAATTTAGACATCATCAAAAACGCTGACTACATTATAGACATGGGGCCTGATGGGGGGGA TAAGGGTGGGAAAGTCATTGCGAGCGGCACGCCTTTAGAAGTGGCGCAAAATTGCGAAAAAACCCAAAGCTATACGGGAA AATTTTTAGCTTTAGAATTGAAATAG
Upstream 100 bases:
>100_bases AACTCTTATGAATAAGAAATGGTAATAAAACCATTCTTTTTTGAAGTATAATAGCTCCTTTTAATCCACTTTCTTATTTT AAGGAATTTTAAGGAAACTC
Downstream 100 bases:
>100_bases CTTGCATGGGGTTTGTTTGTGAAAGAGAATGAACTACCGAAATTATAAAAAATACTAAAAAGCATTTTTTATAATCAATA GTAAAAAGCTTGATTTTAAT
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 941; Mature: 941
Protein sequence:
>941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCLEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENSSRIASAIEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCEYNGIDTALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCEGHRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKDLLQNNHSTALYLNGTKKIERPKLELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKIQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGTKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMIVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Sequences:
>Translated_941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCLEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENSSRIASAIEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCEYNGIDTALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCEGHRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKDLLQNNHSTALYLNGTKKIERPKLELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKIQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGTKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMIVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK >Mature_941_residues MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVD KIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARIGEQFCPTCLEPISSMSASDIISQICHLEENSKIIILAPI IKDKKGSFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENSSRIASAIEKALKESYGELEV EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYN RSYYAQMFEGFCEYNGIDTALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKT CSSCEGHRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIG PKAGRHGGEVVFSGSVKDLLQNNHSTALYLNGTKKIERPKLELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSG SGKSSLILQTLLPTAQTLLNHAKKIQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGTKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKF PKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGN SMIVIEHNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=947, Percent_Identity=51.3199577613516, Blast_Score=910, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104778; Mature: 104778
Theoretical pI: Translated: 7.68; Mature: 7.68
Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYL CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH ESLSSYARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFAR HHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH IGEQFCPTCLEPISSMSASDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGY HHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH VRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENSSRIASAIEKALKESYGELEV HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISK EEEECCCCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHH ILDPNTPLNQGAIKVIFGYNRSYYAQMFEGFCEYNGIDTALCFNELNKEQQDALLYGNGT HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCC EISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEGHRLKASSLSVQVAG EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEC LKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG CHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTL CCCCCCCCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEE IVVEHDKETIKHADFVVDIGPKAGRHGGEVVFSGSVKDLLQNNHSTALYLNGTKKIERPK EEEECCHHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHCCCCCEEEEECCCCCCCCCC LELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLN CCCCCCCCEEEEECCCCCCCCCEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH HAKKIQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI HHHHHHCCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEE LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGTKYNPQTLEIKVKGK EEEECCEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCC SIADVLNMSVEEAYEFFAKFPKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKE HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH LSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMIVIEHNLDIIKNADYIID HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEE MGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK ECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC >Mature Secondary Structure MQHKTIMDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYL CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHH ESLSSYARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFAR HHHHHHHHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH IGEQFCPTCLEPISSMSASDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGY HHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH VRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVINSENSSRIASAIEKALKESYGELEV HHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEE EILQDNAPSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISK EEEECCCCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHH ILDPNTPLNQGAIKVIFGYNRSYYAQMFEGFCEYNGIDTALCFNELNKEQQDALLYGNGT HCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCC EISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEGHRLKASSLSVQVAG EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEC LKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLG CHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC RDARTISGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTL CCCCCCCCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEE IVVEHDKETIKHADFVVDIGPKAGRHGGEVVFSGSVKDLLQNNHSTALYLNGTKKIERPK EEEECCHHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHCCCCCEEEEECCCCCCCCCC LELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLN CCCCCCCCEEEEECCCCCCCCCEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH HAKKIQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKI HHHHHHCCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEE LGYSASRFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGTKYNPQTLEIKVKGK EEEECCEEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCC SIADVLNMSVEEAYEFFAKFPKIAVKLKTLIDVGLGYITLGQNATTLSGGEAQRIKLAKE HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHH LSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMIVIEHNLDIIKNADYIID HHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEE MGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK ECCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]