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The map label for this gene is trxB [H]

Identifier: 188527329

GI number: 188527329

Start: 518909

End: 519844

Strand: Reverse

Name: trxB [H]

Synonym: HPSH_02680

Alternate gene names: 188527329

Gene position: 519844-518909 (Counterclockwise)

Preceding gene: 188527330

Following gene: 188527328

Centisome position: 32.32

GC content: 44.34

Gene sequence:

>936_bases
ATGATAGATTGCGCGATTATTGGAGGTGGTCCTGCAGGTTTGAGTGCGGGGCTTTATGCCACTAGAGGCGGTGTTAAAAA
CGCCGTTTTATTTGAAAAAGGAATGCCTGGGGGGCAAATCACTGGCAGTAGTGAAATTGAAAATTATCCGGGCGTTAAGG
AAGTGGTGAGTGGGTTGGATTTCATGCAACCATGGCAAGAGCAGTGCTTCCGCTTTGGCTTAAAGCATGAGATGACCGCT
GTTCAAAGGGTTTCTAAAAAAGACTCTCATTTTGTTATTTTGGCAGAAGATGGCAAGACTTTTGAAGCTAAGAGCGTGAT
TATCGCTACCGGTGGCAGCCCTAAACGCACAGGCATCAAGGGCGAGTCGGAATATTGGGGTAAAGGCGTTAGCACTTGCG
CAACATGCGATGGCTTCTTTTACAAAAATAAAGAAGTAGCGGTGCTTGGTGGAGGCGATACCGCCGTAGAAGAGGCGATT
TATCTGGCCAACATCTGCAAAAAAGTCTATCTCATCCACAGAAGAGATGGTTTTAGGTGTGCGCCTATCACTTTAGAACA
TGCTAAAAACAATGATAAGATTGAGTTTTTAACCCCTTATGTGGTAGAAGAAATCAAGGGCGATGCTTCTGGCGTGTCTT
CTTTAAGCATTAAGAACACAGCCACTAATGAAACAAGAGAATTAATCGTGCCGGGGTTTTTTATTTTTGTGGGTTATGAT
GTGAATAACGCCGTGTTGAAACAAGAAGACGGCTCCATGCTATGCAAATGCGATGAATACGGCTCTATTGTCGTGGATTT
TTCCATGAAAACAAATGTTCAAGGCTTGTTTGCAGCAGGAGATATTCGCATTTTTGCCCCTAAGCAAGTGGTTTGCGCTG
CAAGCGATGGCGCTACGGCAGCCTTAAGCGTGATTTCTTATTTAGAACACCATTAA

Upstream 100 bases:

>100_bases
TTTTATTCACAAAAGATGGCGAAGTCGTCCATCAGTTGGTGGGTGTGCAAACTAAAGTTGCTTTAAAAGAGCAATTGAAC
AAACTTCTAGGCTAGTAGCC

Downstream 100 bases:

>100_bases
ATCAAGCTCATGACCCTAGATTTAGGGTTATGAGTTCTCGCTTCAAACATTCATTGGATCTTTTAAAGCTTTTTTGTAGC
CGTGATGCGATTTTATTCGC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELIVPGFFIFVGYD
VNNAVLKQEDGSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH

Sequences:

>Translated_311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELIVPGFFIFVGYD
VNNAVLKQEDGSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH
>Mature_311_residues
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFMQPWQEQCFRFGLKHEMTA
VQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIKGESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAI
YLANICKKVYLIHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELIVPGFFIFVGYD
VNNAVLKQEDGSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATAALSVISYLEHH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=36.5384615384615, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=37.2611464968153, Blast_Score=192, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=36.624203821656, Blast_Score=180, Evalue=2e-46,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33469; Mature: 33469

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLD
CEEEEEECCCHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCC
GESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRC
CCHHHCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCEE
APITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELIVPGFFIFVGYD
EEEEEECCCCCCCEEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECEEEEEEEEC
VNNAVLKQEDGSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATA
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCEEEEECCEEEECCCEEEEECCCCCHH
ALSVISYLEHH
HHHHHHHHHCC
>Mature Secondary Structure
MIDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLD
CEEEEEECCCHHCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHH
FMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAEDGKTFEAKSVIIATGGSPKRTGIK
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCC
GESEYWGKGVSTCATCDGFFYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGFRC
CCHHHCCCCCCHHEECCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCCEE
APITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNETRELIVPGFFIFVGYD
EEEEEECCCCCCCEEEECHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEECEEEEEEEEC
VNNAVLKQEDGSMLCKCDEYGSIVVDFSMKTNVQGLFAAGDIRIFAPKQVVCAASDGATA
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCEEEEECCEEEECCCEEEEECCCCCHH
ALSVISYLEHH
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]