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The map label for this gene is ykpA [H]

Identifier: 188527300

GI number: 188527300

Start: 488818

End: 490419

Strand: Direct

Name: ykpA [H]

Synonym: HPSH_02535

Alternate gene names: 188527300

Gene position: 488818-490419 (Clockwise)

Preceding gene: 188527298

Following gene: 188527301

Centisome position: 30.39

GC content: 41.7

Gene sequence:

>1602_bases
ATGCTACAAACCATCAACTTAACGCAACGCTATGCGACTAAAAAATTGTTTGAGAATGTGAATATCAAGCTGGATAAAAA
CAAACGCTACGGGCTGATTGGGGCTAATGGTGCAGGAAAATCCACTTTTTTAAAGATTTTAAGCAAGAGCATTGATTGTA
GCAGTGGGGAAGTCATCATCACAAGCGGGATGAGAATGGGGGTTTTAGGGCAGGATCAATACGCTTTTGAAGATTTGAGC
CTTAAAGATGCGGTTTTGATAGGCAATAAGCGTTTGTATGACGCTATCAAAGAAAAAGAGCGCTTATACATTGAAGGCGA
TTTGAGCGATGATAAAGTGAATGCTAGGCTAGGGGAGTTAGAAACCATTTGCGTAGAAGAAGATCCCATGTATGAATGCG
AAGTGGTGATTGAAAAAATCCTAGAAGATTTAGGCATTCCTAGCTCCAGGCACAATGATTTGATGAAAACCTTGCCAAGC
AGCGATAAGTTTAAAATCCTTCTCGCTCAAGTTTTATTCCCTAAACCGGATATTTTGCTTTTAGATGAGCCGACCAACAA
CCTGGATTTAAACGCCATTGAATGGCTAGAAAACAACCTCAAACGCCATGAAGGCACGATGGTAGTCATCAGCCATGACA
GGCATTTTTTAAATGCGGTATGCACGCATATTTTGGATTTGGATTTTCACAGCGTGCGCGAATTTAGCGGGAATTATGAC
GATTGGTATATCGCTTCTACTTTGATGATTAAACAGCAAGAGGCCGAACGCAATAAAAAACTCAAAGAAAAAGAAGAGCT
AGAAAAATTCATCGCTCGTTTCAGCGCTAACGCTTCTAAAGCTAAGCAAGCCACCAGCCGCCAAAAACAACTGGATAAAT
TAGACATTCAAAGCTTAGCGGTATCTAGCAGGAGGGATCCTAGCATTATTTTTAAACCCAAACGCACCATTGGTAATGAA
GCCTTAGAGTGCGAAAACATCTCTAAAAGTTATGACGGGCAAATCGTTTTAAATCAAGTGAGCCTGAAAGTGATGCCTAA
AGACAAGATCGCCCTCATAGGACCAAACGGCGTGGGTAAATCCACGCTTTGTAAGATTTTAGTAGAAGAGTTAAAGCCGG
ATACGGGCGTGGTGAAATGGGGAGCGACCGTTTCAAAAGGCTATTTCCCTCAAAATGTGAGCGAAGAAATCAGCGGGGAA
GAGACCTTGTACCAATGGCTTTTTAACTTCAATAAAAAGATTGAAAGTGCAGAGGTTAGGAACGCTTTAGGGAGGATGCT
TTTTAATGGCGAAGAGCAAGAAAAATGCGTGAACGCTTTAAGCGGAGGCGAAAAACACCGAATGGTTTTATCCAAGCTCA
TGCTAGAGGGGGGGAATTTCTTAGTCTTAGATGAGCCAACCAACCACCTAGATTTAGAAGCCATCATTGCGCTAGGCGAA
GCGCTCTTTAAATTTGATGGGGCAGTAATTTGCATAAGCCATGACAGAGAGCTCATTGATGCGTATGCTAATAGAATCAT
TGAATTAGTCCCAAGCCCTAAAGGCGCTTCAATCATTGATTTTAAGGGCAGTTATGAAGAGTATTTAGCGAGCAAAAGAT
GA

Upstream 100 bases:

>100_bases
CAAAGATCTTGCAGATAACCATAATAAGCAAGGGATACAATATTGTAAAGAAAACGCTACAATAAACTTTCTCTAATCAC
AAAAATAAGGAAATCATAAG

Downstream 100 bases:

>100_bases
AACCACAAGATATTGGAATCATTCAAAGCGTTTTAGAGATTATCAAAGAGCCTATTAAGGTTACTGAAGTTTATGATAAA
GCCCAAGAGCTTTTTGAAAA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYIEGDLSDDKVNARLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLMIKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDTGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKR

Sequences:

>Translated_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYIEGDLSDDKVNARLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLMIKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDTGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKR
>Mature_533_residues
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVIITSGMRMGVLGQDQYAFEDLS
LKDAVLIGNKRLYDAIKEKERLYIEGDLSDDKVNARLGELETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPS
SDKFKILLAQVLFPKPDILLLDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
DWYIASTLMIKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLAVSSRRDPSIIFKPKRTIGNE
ALECENISKSYDGQIVLNQVSLKVMPKDKIALIGPNGVGKSTLCKILVEELKPDTGVVKWGATVSKGYFPQNVSEEISGE
ETLYQWLFNFNKKIESAEVRNALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKR

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI10947137, Length=541, Percent_Identity=31.6081330868762, Blast_Score=238, Evalue=8e-63,
Organism=Homo sapiens, GI27881506, Length=541, Percent_Identity=31.6081330868762, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI148612853, Length=543, Percent_Identity=30.2025782688766, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI69354671, Length=535, Percent_Identity=31.214953271028, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI10947135, Length=535, Percent_Identity=31.214953271028, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1787041, Length=533, Percent_Identity=42.7767354596623, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1789751, Length=525, Percent_Identity=32, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI2367384, Length=532, Percent_Identity=32.3308270676692, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1787182, Length=547, Percent_Identity=29.7989031078611, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1788165, Length=193, Percent_Identity=32.6424870466321, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788897, Length=538, Percent_Identity=21.5613382899628, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=28.0952380952381, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788225, Length=222, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787029, Length=245, Percent_Identity=21.2244897959184, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=524, Percent_Identity=31.6793893129771, Blast_Score=245, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17555318, Length=515, Percent_Identity=29.9029126213592, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17559834, Length=509, Percent_Identity=30.4518664047151, Blast_Score=218, Evalue=8e-57,
Organism=Saccharomyces cerevisiae, GI6320874, Length=505, Percent_Identity=33.8613861386139, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6321121, Length=538, Percent_Identity=30.6691449814126, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6325030, Length=408, Percent_Identity=26.9607843137255, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=420, Percent_Identity=25.4761904761905, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323278, Length=416, Percent_Identity=23.5576923076923, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24666836, Length=501, Percent_Identity=32.7345309381238, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24642252, Length=540, Percent_Identity=29.4444444444444, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI18859989, Length=540, Percent_Identity=29.4444444444444, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=29.7709923664122, Blast_Score=216, Evalue=5e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60032; Mature: 60032

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMRMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYIEGDLSDDKVNARLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHCCCEEEEECCCCCCHHHHHHCCE
ETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLMIKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDGQIVLNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDTGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKR
HHHHCCCEEEEEECCHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHCCCC
>Mature Secondary Structure
MLQTINLTQRYATKKLFENVNIKLDKNKRYGLIGANGAGKSTFLKILSKSIDCSSGEVII
CCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEE
TSGMRMGVLGQDQYAFEDLSLKDAVLIGNKRLYDAIKEKERLYIEGDLSDDKVNARLGEL
ECCCEECCCCCCCHHHCCCCCCCEEEECCHHHHHHHHCCCEEEEECCCCCCHHHHHHCCE
ETICVEEDPMYECEVVIEKILEDLGIPSSRHNDLMKTLPSSDKFKILLAQVLFPKPDILL
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCCEEE
LDEPTNNLDLNAIEWLENNLKRHEGTMVVISHDRHFLNAVCTHILDLDFHSVREFSGNYD
EECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHCCCCC
DWYIASTLMIKQQEAERNKKLKEKEELEKFIARFSANASKAKQATSRQKQLDKLDIQSLA
CEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VSSRRDPSIIFKPKRTIGNEALECENISKSYDGQIVLNQVSLKVMPKDKIALIGPNGVGK
HCCCCCCCEEECCCHHCCCCHHHHHCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCH
STLCKILVEELKPDTGVVKWGATVSKGYFPQNVSEEISGEETLYQWLFNFNKKIESAEVR
HHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHH
NALGRMLFNGEEQEKCVNALSGGEKHRMVLSKLMLEGGNFLVLDEPTNHLDLEAIIALGE
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
ALFKFDGAVICISHDRELIDAYANRIIELVPSPKGASIIDFKGSYEEYLASKR
HHHHCCCEEEEEECCHHHHHHHHHHHEEECCCCCCCEEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]