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The map label for this gene is gmhA [H]

Identifier: 188527298

GI number: 188527298

Start: 486837

End: 487415

Strand: Direct

Name: gmhA [H]

Synonym: HPSH_02525

Alternate gene names: 188527298

Gene position: 486837-487415 (Clockwise)

Preceding gene: 188527297

Following gene: 188527300

Centisome position: 30.27

GC content: 40.76

Gene sequence:

>579_bases
ATGATTGATGGTTTGATTAAAAAAGAATTTTTAGCCCATAAGGAAGCGTTAGAAAAAAGTTTAGAAAGTTTGCAAGAAGC
GTTAAAACAAAGCGTTCATCTTTTGATAGAAACTTTAGAAAACCAAGGGAAAATCCTTATTTGCGGTAACGGGGGGAGCG
CTAGCGATGCGCAACATTTTGCCGCTGAATTGACCGGGCGCTATAAATTGGAAAGGAAAGGCTTGAGCGCCTTAAGCTTA
AGCACGGATACCTCAGCCCTCACCGCCATTGCGAACGATTATGGTTATGAAGAAGTGTTTGCCAGACAAGTAGAAGCGTT
GGGGGTAAAAAACGATGTTTTGATAGGGATTTCTACAAGCGGTAATTCCAAAAATGTCCTAAAAGCTTATGAAAAAGCCA
AAGATTTAGGGGTAAAAACGCTTAGTTTAGCGGGGCGTGATGGGGGGAAAATGAAGCCTTTAAGCGACATGGCTTTGATT
GTCCCTAGCGATGATACCCCACGAATCCAAGAAATGCACATTCTTATGATCCACATTTTATGCGATTGCATTGAAAGGCA
TTTCGCTAATAAAAATTAA

Upstream 100 bases:

>100_bases
GAAATCATAGGGAGCGAGTTTGCTAAAGAAACCCGTTTGATGGAGTTTGAAGAAGGTTATTCCACAAGCGCTATCATAGA
AAGAATTAAAAGGACATGCA

Downstream 100 bases:

>100_bases
ATTCAAAGGCTATGCACTTGAATTTAACAAGAAAATGATTCCACAATGATCCCACAAGATACAATGAAAATAAAGAAAGG
ATTAAAAACAACAAAAATCT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MIDGLIKKEFLAHKEALEKSLESLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSALSL
STDTSALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLGVKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFANKN

Sequences:

>Translated_192_residues
MIDGLIKKEFLAHKEALEKSLESLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSALSL
STDTSALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLGVKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFANKN
>Mature_192_residues
MIDGLIKKEFLAHKEALEKSLESLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSALSL
STDTSALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLGVKTLSLAGRDGGKMKPLSDMALI
VPSDDTPRIQEMHILMIHILCDCIERHFANKN

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=189, Percent_Identity=44.973544973545, Blast_Score=159, Evalue=9e-41,
Organism=Escherichia coli, GI1789539, Length=183, Percent_Identity=43.7158469945355, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20909; Mature: 20909

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGLIKKEFLAHKEALEKSLESLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAELTGRYKLERKGLSALSLSTDTSALTAIANDYGYEEVFARQVEALGVKNDVLIGISTS
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECC
GNSKNVLKAYEKAKDLGVKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHIL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CDCIERHFANKN
HHHHHHHHCCCC
>Mature Secondary Structure
MIDGLIKKEFLAHKEALEKSLESLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
AAELTGRYKLERKGLSALSLSTDTSALTAIANDYGYEEVFARQVEALGVKNDVLIGISTS
HHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECC
GNSKNVLKAYEKAKDLGVKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHIL
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
CDCIERHFANKN
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA