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The map label for this gene is tdhA [H]

Identifier: 188527279

GI number: 188527279

Start: 467884

End: 470259

Strand: Reverse

Name: tdhA [H]

Synonym: HPSH_02430

Alternate gene names: 188527279

Gene position: 470259-467884 (Counterclockwise)

Preceding gene: 188527283

Following gene: 188527277

Centisome position: 29.23

GC content: 43.9

Gene sequence:

>2376_bases
ATGTTTTTAAGATCATATCCAAAGCTTAGATACGCTTTGTGTTTCCCCCTACTCGCTGATACTTGCTATAGCGAAGAGCG
CACTTTAAATAAGGTTACCACCCAAGCTAAAAGGATTTTCACTTACAACAATGAGTTTAAGGTAACTTCTAAAGAATTGG
ATCAACGCCAAAGCAATGAAGTCAAGGACTTGTTTAGGACTAACCCTGATGTGAATGTGGGCGGAGGGAGCGTGATGGGA
CAGAAAATCTATGTGAGAGGCATTGAAGACAGGCTTTTAAGGGTTACGGTGGATGGGGCTGCGCAAAATGGCAATATCTA
CCACCACCAAGGCAACACCGTGATTGACCCTGGCATGCTTAAAAGCGTGGAAGTTACCAAAGGATCAGCGAATGCAAGCG
CAGGGCCAGGAGCGATCGCAGGAGTGATTAAAATGGAGACTAAAGGAGCAGCTGATTTTATCCCTAGGGGGAAAAATTAT
GCAGCGAGTGGGGCGGTGAGTTTTTATACCAATTTTGGCGATCGAGAGACTTTTAGATCGGCTTACCAAAACGCGCATTT
TGATATTATCGCTTACTACACGCACCAAAACATCTTCTATTATAGAAGCGGCGCTACAGCGATGAAAAACCTTTTCAATC
CCACACAAGCCGATAAAGAGCCAGGAACTCCTAGCGAGCAAAACAACGCTTTAGTTAAAATGAATGGTTATTTGAGCGAT
AGAGACACGCTCACTTTCAGCTGGAACATGACACGAGATAACGCTACACGCCCTTTAAGGAGTAACGCTATAGGGTTAGC
CTATCCTTGTGAAGCCCCTTTTAGCCCTGATAGCGACCAAGGGTGTCCTAATGTGTTGGATAGTTTCACAAGATACATGT
ATCACTCCATCAATAGCGCTAACAATCTTTCCTTACAATACAAAAGGGAAGCGGGAAATTCTTTTGGCGACCCACGATTA
GATTTTACCCTTTATACAAGCATTAGAAACGCCAAGTTTGATCCCCTATTTGATCCTAATGGCGTTTATGCTAAATTCCC
CACTTCTCAAGCGAGCGCATGGGAAAAAGAAAATTACCCATGCGTTGAAGGCGGGTATTGCACCCCAAGCTTTTCAGATG
TGGATAAACCAAGCTCACAGCCTAGGGATTTGTTTTTAAACAACACCGGCTTAAACCTTAAAATCGCGCATGTGATTGAT
GAAGCCACAGACAGCCTTTTTGAATACGGATTCAACTACCAAAATTTAAGCGTTTTTGACGCTCGCATCCCTAAATCAGA
GTTATACAGGCCTAATCAAGTTTATACTGATGATAAAGGGCAAAAACAAATCGCTTGCTCTCTTGTGGATAATAACCCCA
ATGATCCTACTTTGTGCCAAAGAGGGAAAGCGAACGGGAATATTTATGGAGGCTATGTGCAAGCGAATTACTCACCTCAT
AAAATCATCACTTTTGGAGCCGGGGTAAGGTGGGACGCATACACGCTTTATGATAAAGACTGGAACCACCGCTACACTCA
AGGCTTTAGCCCTAGCGCGGCTCTTGTGATCAGCCCCATTGAGCCTTTATCTTTAAAAATCACTTATTCTCAAGTTACAA
GGGGGGTTATGCCAGGAGATGGCGTGTATATGCGCCAAAACGATTTACGATACGCTAAAAATATCAAGCCTGAAGTGGGC
TCTAACGCTGAATTTAATATTGATTATTCAAGCCAGTATTTTAGCGGGAGGGCTGCGGCGTTTTATCAGGCTCTGGATAA
TTTCATCTCACAATACGCGCAAAGTTTGATTGTAACCAATTTGAGTCAAGCGATTAGGATTTATGGCTATGAAGTGGGTG
GGACTTTCAAATACAAGGGCGTGAGTTTGAATGTGGGGATCTCGCGCACTTGGCCCACCACTAGGGGGTATTTAATGGCA
GACAGCTATGAGCTTGCCGCAAGCACCGGTAATGTTTTTATCATTAAATTGGATTACACCATCCCCAAAACAGGGATCAA
TCTTGCTTGGCTTAGCCGCTTTGTTACCGGTTTAGATTATTGCGGGTTTGATATTTACTTGCCTGATTACGGGACGGCTG
AAAAACCCAAAACCCCTACCGATTTAGCCAAATGCGGATCCCAATTAGGGTTAGTGCATATGCATAAACCGGGCTATGGC
GTGAGTAATTTTTATATCAATTGGAGTCCTAAAACCAAAAGCCGCTGGAAAGGTTTGTTGCTTTCAGCCGTGTTCAATAA
TGTTTTCAACAAATTCTATGTGGATCAAACAAGCCCTTATGTCATGAGCCCGGACATGCCAGGCACTGACGCTATTAAAA
GAGCGATCGCAGAGCCCGGGTTTAACGCGCGCTTTGAAGTGGCTTACAAATGGTGA

Upstream 100 bases:

>100_bases
TAATTATCATACTATTATATCTCAATGCATTGACGGATTTTGTTTTTTTTTTTTTGTATTTTTATTTTTTTTGAATTTTT
AAATTAAGGAGAGTTGTTTG

Downstream 100 bases:

>100_bases
TTAGTGGGGTTTTAAGCGTTGCGCATGCGTGATAGCAACGGCTATCGCATCGCTAATATCCAAAGGCTTGATTTCGCTTG
TGATGTTAAGCAAGCGTTTG

Product: iron-regulated outer membrane protein (frpB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MFLRSYPKLRYALCFPLLADTCYSEERTLNKVTTQAKRIFTYNNEFKVTSKELDQRQSNEVKDLFRTNPDVNVGGGSVMG
QKIYVRGIEDRLLRVTVDGAAQNGNIYHHQGNTVIDPGMLKSVEVTKGSANASAGPGAIAGVIKMETKGAADFIPRGKNY
AASGAVSFYTNFGDRETFRSAYQNAHFDIIAYYTHQNIFYYRSGATAMKNLFNPTQADKEPGTPSEQNNALVKMNGYLSD
RDTLTFSWNMTRDNATRPLRSNAIGLAYPCEAPFSPDSDQGCPNVLDSFTRYMYHSINSANNLSLQYKREAGNSFGDPRL
DFTLYTSIRNAKFDPLFDPNGVYAKFPTSQASAWEKENYPCVEGGYCTPSFSDVDKPSSQPRDLFLNNTGLNLKIAHVID
EATDSLFEYGFNYQNLSVFDARIPKSELYRPNQVYTDDKGQKQIACSLVDNNPNDPTLCQRGKANGNIYGGYVQANYSPH
KIITFGAGVRWDAYTLYDKDWNHRYTQGFSPSAALVISPIEPLSLKITYSQVTRGVMPGDGVYMRQNDLRYAKNIKPEVG
SNAEFNIDYSSQYFSGRAAAFYQALDNFISQYAQSLIVTNLSQAIRIYGYEVGGTFKYKGVSLNVGISRTWPTTRGYLMA
DSYELAASTGNVFIIKLDYTIPKTGINLAWLSRFVTGLDYCGFDIYLPDYGTAEKPKTPTDLAKCGSQLGLVHMHKPGYG
VSNFYINWSPKTKSRWKGLLLSAVFNNVFNKFYVDQTSPYVMSPDMPGTDAIKRAIAEPGFNARFEVAYKW

Sequences:

>Translated_791_residues
MFLRSYPKLRYALCFPLLADTCYSEERTLNKVTTQAKRIFTYNNEFKVTSKELDQRQSNEVKDLFRTNPDVNVGGGSVMG
QKIYVRGIEDRLLRVTVDGAAQNGNIYHHQGNTVIDPGMLKSVEVTKGSANASAGPGAIAGVIKMETKGAADFIPRGKNY
AASGAVSFYTNFGDRETFRSAYQNAHFDIIAYYTHQNIFYYRSGATAMKNLFNPTQADKEPGTPSEQNNALVKMNGYLSD
RDTLTFSWNMTRDNATRPLRSNAIGLAYPCEAPFSPDSDQGCPNVLDSFTRYMYHSINSANNLSLQYKREAGNSFGDPRL
DFTLYTSIRNAKFDPLFDPNGVYAKFPTSQASAWEKENYPCVEGGYCTPSFSDVDKPSSQPRDLFLNNTGLNLKIAHVID
EATDSLFEYGFNYQNLSVFDARIPKSELYRPNQVYTDDKGQKQIACSLVDNNPNDPTLCQRGKANGNIYGGYVQANYSPH
KIITFGAGVRWDAYTLYDKDWNHRYTQGFSPSAALVISPIEPLSLKITYSQVTRGVMPGDGVYMRQNDLRYAKNIKPEVG
SNAEFNIDYSSQYFSGRAAAFYQALDNFISQYAQSLIVTNLSQAIRIYGYEVGGTFKYKGVSLNVGISRTWPTTRGYLMA
DSYELAASTGNVFIIKLDYTIPKTGINLAWLSRFVTGLDYCGFDIYLPDYGTAEKPKTPTDLAKCGSQLGLVHMHKPGYG
VSNFYINWSPKTKSRWKGLLLSAVFNNVFNKFYVDQTSPYVMSPDMPGTDAIKRAIAEPGFNARFEVAYKW
>Mature_791_residues
MFLRSYPKLRYALCFPLLADTCYSEERTLNKVTTQAKRIFTYNNEFKVTSKELDQRQSNEVKDLFRTNPDVNVGGGSVMG
QKIYVRGIEDRLLRVTVDGAAQNGNIYHHQGNTVIDPGMLKSVEVTKGSANASAGPGAIAGVIKMETKGAADFIPRGKNY
AASGAVSFYTNFGDRETFRSAYQNAHFDIIAYYTHQNIFYYRSGATAMKNLFNPTQADKEPGTPSEQNNALVKMNGYLSD
RDTLTFSWNMTRDNATRPLRSNAIGLAYPCEAPFSPDSDQGCPNVLDSFTRYMYHSINSANNLSLQYKREAGNSFGDPRL
DFTLYTSIRNAKFDPLFDPNGVYAKFPTSQASAWEKENYPCVEGGYCTPSFSDVDKPSSQPRDLFLNNTGLNLKIAHVID
EATDSLFEYGFNYQNLSVFDARIPKSELYRPNQVYTDDKGQKQIACSLVDNNPNDPTLCQRGKANGNIYGGYVQANYSPH
KIITFGAGVRWDAYTLYDKDWNHRYTQGFSPSAALVISPIEPLSLKITYSQVTRGVMPGDGVYMRQNDLRYAKNIKPEVG
SNAEFNIDYSSQYFSGRAAAFYQALDNFISQYAQSLIVTNLSQAIRIYGYEVGGTFKYKGVSLNVGISRTWPTTRGYLMA
DSYELAASTGNVFIIKLDYTIPKTGINLAWLSRFVTGLDYCGFDIYLPDYGTAEKPKTPTDLAKCGSQLGLVHMHKPGYG
VSNFYINWSPKTKSRWKGLLLSAVFNNVFNKFYVDQTSPYVMSPDMPGTDAIKRAIAEPGFNARFEVAYKW

Specific function: Heme receptor [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

None

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 88534; Mature: 88534

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLRSYPKLRYALCFPLLADTCYSEERTLNKVTTQAKRIFTYNNEFKVTSKELDQRQSNE
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCEEEEHHHHHHHHHHH
VKDLFRTNPDVNVGGGSVMGQKIYVRGIEDRLLRVTVDGAAQNGNIYHHQGNTVIDPGML
HHHHHHCCCCCCCCCCCEECCEEEEEECCCEEEEEEECCCCCCCCEEEECCCEEECCCCC
KSVEVTKGSANASAGPGAIAGVIKMETKGAADFIPRGKNYAASGAVSFYTNFGDRETFRS
EEEEEECCCCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCCCEEEEEECCCCHHHHHH
AYQNAHFDIIAYYTHQNIFYYRSGATAMKNLFNPTQADKEPGTPSEQNNALVKMNGYLSD
HHCCCCEEEEEEEEECEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEECC
RDTLTFSWNMTRDNATRPLRSNAIGLAYPCEAPFSPDSDQGCPNVLDSFTRYMYHSINSA
CCEEEEEEEECCCCCCCCHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
NNLSLQYKREAGNSFGDPRLDFTLYTSIRNAKFDPLFDPNGVYAKFPTSQASAWEKENYP
CCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
CVEGGYCTPSFSDVDKPSSQPRDLFLNNTGLNLKIAHVIDEATDSLFEYGFNYQNLSVFD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEE
ARIPKSELYRPNQVYTDDKGQKQIACSLVDNNPNDPTLCQRGKANGNIYGGYVQANYSPH
CCCCHHHCCCCCCEECCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEEEECCCCC
KIITFGAGVRWDAYTLYDKDWNHRYTQGFSPSAALVISPIEPLSLKITYSQVTRGVMPGD
EEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCCCCCCC
GVYMRQNDLRYAKNIKPEVGSNAEFNIDYSSQYFSGRAAAFYQALDNFISQYAQSLIVTN
CEEEECCCCHHHHCCCCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSQAIRIYGYEVGGTFKYKGVSLNVGISRTWPTTRGYLMADSYELAASTGNVFIIKLDYT
HHHEEEEEEEEECCEEEECCEEEECCEEECCCCCCCEEEECCEEEEECCCCEEEEEEECC
IPKTGINLAWLSRFVTGLDYCGFDIYLPDYGTAEKPKTPTDLAKCGSQLGLVHMHKPGYG
CCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHCCHHCCEEEEECCCCC
VSNFYINWSPKTKSRWKGLLLSAVFNNVFNKFYVDQTSPYVMSPDMPGTDAIKRAIAEPG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCHHHHHHHHHCCC
FNARFEVAYKW
CCCEEEEEEEC
>Mature Secondary Structure
MFLRSYPKLRYALCFPLLADTCYSEERTLNKVTTQAKRIFTYNNEFKVTSKELDQRQSNE
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEECCCEEEEHHHHHHHHHHH
VKDLFRTNPDVNVGGGSVMGQKIYVRGIEDRLLRVTVDGAAQNGNIYHHQGNTVIDPGML
HHHHHHCCCCCCCCCCCEECCEEEEEECCCEEEEEEECCCCCCCCEEEECCCEEECCCCC
KSVEVTKGSANASAGPGAIAGVIKMETKGAADFIPRGKNYAASGAVSFYTNFGDRETFRS
EEEEEECCCCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCCCEEEEEECCCCHHHHHH
AYQNAHFDIIAYYTHQNIFYYRSGATAMKNLFNPTQADKEPGTPSEQNNALVKMNGYLSD
HHCCCCEEEEEEEEECEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEECC
RDTLTFSWNMTRDNATRPLRSNAIGLAYPCEAPFSPDSDQGCPNVLDSFTRYMYHSINSA
CCEEEEEEEECCCCCCCCHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
NNLSLQYKREAGNSFGDPRLDFTLYTSIRNAKFDPLFDPNGVYAKFPTSQASAWEKENYP
CCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
CVEGGYCTPSFSDVDKPSSQPRDLFLNNTGLNLKIAHVIDEATDSLFEYGFNYQNLSVFD
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEE
ARIPKSELYRPNQVYTDDKGQKQIACSLVDNNPNDPTLCQRGKANGNIYGGYVQANYSPH
CCCCHHHCCCCCCEECCCCCCCEEEEEEECCCCCCCHHHHCCCCCCCEEEEEEEECCCCC
KIITFGAGVRWDAYTLYDKDWNHRYTQGFSPSAALVISPIEPLSLKITYSQVTRGVMPGD
EEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEEEHHHHHCCCCCCC
GVYMRQNDLRYAKNIKPEVGSNAEFNIDYSSQYFSGRAAAFYQALDNFISQYAQSLIVTN
CEEEECCCCHHHHCCCCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSQAIRIYGYEVGGTFKYKGVSLNVGISRTWPTTRGYLMADSYELAASTGNVFIIKLDYT
HHHEEEEEEEEECCEEEECCEEEECCEEECCCCCCCEEEECCEEEEECCCCEEEEEEECC
IPKTGINLAWLSRFVTGLDYCGFDIYLPDYGTAEKPKTPTDLAKCGSQLGLVHMHKPGYG
CCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHCCHHCCEEEEECCCCC
VSNFYINWSPKTKSRWKGLLLSAVFNNVFNKFYVDQTSPYVMSPDMPGTDAIKRAIAEPG
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCHHHHHHHHHCCC
FNARFEVAYKW
CCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9712775 [H]