Click here to switch to the map view.

The map label for this gene is hsdS [H]

Identifier: 188527246

GI number: 188527246

Start: 432577

End: 433692

Strand: Reverse

Name: hsdS [H]

Synonym: HPSH_02265

Alternate gene names: 188527246

Gene position: 433692-432577 (Counterclockwise)

Preceding gene: 188527247

Following gene: 188527245

Centisome position: 26.96

GC content: 31.09

Gene sequence:

>1116_bases
TTGAGTAAAACTCTACAAGACTACGCAACTTTAATCAATGATACCATACAATCAAATGAAATCAATCACTATATCACCAC
AGCTAACATGTGCCAAAATTTAGGCGGTATTGATACATTTAAAAACATCAATATCCCACAAGGAAAGGTCAGATCATTTC
AAAAAGATGATGTTTTGTTGTCAAATATAGACCCTTGGCATAGACAAGTCTATATGGCAAAACAAAAAGGCGGTTGCAGT
TCTGATGTCCTAGTGTTTAGGGCTAAACACATTGATAGCGCCACACTTTTTGCGATTTTATCTAGTCAATCTTTTATCAA
TTATTTATGTTTAGGAAGTGTCGGTTCAAAGAGAAAAAGGGGAGATAAAACACACATGATGGATTTCAAAATCCCTACAA
TCAATTTTACAATCGCTAAAATTTTTAATAGCATTCAAAATAAGATTGAAAACAACCACAAAATCAATGAGATTTTACAC
AAAATCCTAGAACTTCTTTATGAGCAATACTTCGTTCGTTTTGATTTTTTAGATGAAAACAACAAACCCTATCAAACTAG
CGGCGGAAAAATGAAATTTTCTAAAGAATTAAACCGCCTTATCCCCAACGATTTTGAAGTTAAAACGCTAGGGGAATTAA
CCCAATTAAAAGTAGGAAACAAAAATGCTAATCACTCATCTAATCAAGGAAAATATCCATTTTTTACTTGCTCAAACAAT
CCTTTAAGATGCGAAACATATCAATTTGAAGGAAAACATATTATTATTTCTGGGAATGGAAATTTTTATGTTACACATTA
TGATGGGAAATTTGATGCCTATCAAAGAACATATGTTGTAAGTCCAAATAATCCAAATCACTATGTTTTAATATATTTAT
TTGTAAAATCATATACAAATTACTTAAAATTACAATCTCGTGGTTCTATTATTAAATTTATTACAAAATCAGATATTGAA
GATATTAAAATCGTATTACCAAATTTAAAAACCTATGCCAAATGGAACAATGTATTAAAAATGATTGAGAACAACATGCA
ATCAACCCAAACCCTAACCGCGCTCAGAGATTTTCTACTCCCCCTACTCCTAAAACAGCAAGTCAAACCCCAATGA

Upstream 100 bases:

>100_bases
GAAAACTTAATGCAGCAATATTCAAGCGAATTAACAAGCCTTTTTGATGAAAGCCAGAGCTTGCAACAAGAAATTTTAGA
AACTTTAAAAGGGGTTAGGT

Downstream 100 bases:

>100_bases
AAAATTTTAAAACAAAACTTTTTGAGGGGTAAAAACCCTTTAGTTACAAGAAAGAGAAGTTTTGTCATCAAAAGAAATTT
TTTAAAGAAAAAGAAGTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: S.EcoDI; Type I restriction enzyme EcoDI specificity protein; S protein [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSKTLQDYATLINDTIQSNEINHYITTANMCQNLGGIDTFKNINIPQGKVRSFQKDDVLLSNIDPWHRQVYMAKQKGGCS
SDVLVFRAKHIDSATLFAILSSQSFINYLCLGSVGSKRKRGDKTHMMDFKIPTINFTIAKIFNSIQNKIENNHKINEILH
KILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGELTQLKVGNKNANHSSNQGKYPFFTCSNN
PLRCETYQFEGKHIIISGNGNFYVTHYDGKFDAYQRTYVVSPNNPNHYVLIYLFVKSYTNYLKLQSRGSIIKFITKSDIE
DIKIVLPNLKTYAKWNNVLKMIENNMQSTQTLTALRDFLLPLLLKQQVKPQ

Sequences:

>Translated_371_residues
MSKTLQDYATLINDTIQSNEINHYITTANMCQNLGGIDTFKNINIPQGKVRSFQKDDVLLSNIDPWHRQVYMAKQKGGCS
SDVLVFRAKHIDSATLFAILSSQSFINYLCLGSVGSKRKRGDKTHMMDFKIPTINFTIAKIFNSIQNKIENNHKINEILH
KILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGELTQLKVGNKNANHSSNQGKYPFFTCSNN
PLRCETYQFEGKHIIISGNGNFYVTHYDGKFDAYQRTYVVSPNNPNHYVLIYLFVKSYTNYLKLQSRGSIIKFITKSDIE
DIKIVLPNLKTYAKWNNVLKMIENNMQSTQTLTALRDFLLPLLLKQQVKPQ
>Mature_370_residues
SKTLQDYATLINDTIQSNEINHYITTANMCQNLGGIDTFKNINIPQGKVRSFQKDDVLLSNIDPWHRQVYMAKQKGGCSS
DVLVFRAKHIDSATLFAILSSQSFINYLCLGSVGSKRKRGDKTHMMDFKIPTINFTIAKIFNSIQNKIENNHKINEILHK
ILELLYEQYFVRFDFLDENNKPYQTSGGKMKFSKELNRLIPNDFEVKTLGELTQLKVGNKNANHSSNQGKYPFFTCSNNP
LRCETYQFEGKHIIISGNGNFYVTHYDGKFDAYQRTYVVSPNNPNHYVLIYLFVKSYTNYLKLQSRGSIIKFITKSDIED
IKIVLPNLKTYAKWNNVLKMIENNMQSTQTLTALRDFLLPLLLKQQVKPQ

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 42852; Mature: 42721

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTLQDYATLINDTIQSNEINHYITTANMCQNLGGIDTFKNINIPQGKVRSFQKDDVLL
CCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEE
SNIDPWHRQVYMAKQKGGCSSDVLVFRAKHIDSATLFAILSSQSFINYLCLGSVGSKRKR
CCCCHHHHHEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHEECCCCCCCCC
GDKTHMMDFKIPTINFTIAKIFNSIQNKIENNHKINEILHKILELLYEQYFVRFDFLDEN
CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCC
NKPYQTSGGKMKFSKELNRLIPNDFEVKTLGELTQLKVGNKNANHSSNQGKYPFFTCSNN
CCCEECCCCCEEHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCEEEECCC
PLRCETYQFEGKHIIISGNGNFYVTHYDGKFDAYQRTYVVSPNNPNHYVLIYLFVKSYTN
CEEEEEEEECCCEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHH
YLKLQSRGSIIKFITKSDIEDIKIVLPNLKTYAKWNNVLKMIENNMQSTQTLTALRDFLL
HEEECCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLLKQQVKPQ
HHHHHHHCCCC
>Mature Secondary Structure 
SKTLQDYATLINDTIQSNEINHYITTANMCQNLGGIDTFKNINIPQGKVRSFQKDDVLL
CCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCEEE
SNIDPWHRQVYMAKQKGGCSSDVLVFRAKHIDSATLFAILSSQSFINYLCLGSVGSKRKR
CCCCHHHHHEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHEECCCCCCCCC
GDKTHMMDFKIPTINFTIAKIFNSIQNKIENNHKINEILHKILELLYEQYFVRFDFLDEN
CCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEECCC
NKPYQTSGGKMKFSKELNRLIPNDFEVKTLGELTQLKVGNKNANHSSNQGKYPFFTCSNN
CCCEECCCCCEEHHHHHHHHCCCCCCCHHHHHHHHEEECCCCCCCCCCCCCCCEEEECCC
PLRCETYQFEGKHIIISGNGNFYVTHYDGKFDAYQRTYVVSPNNPNHYVLIYLFVKSYTN
CEEEEEEEECCCEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEEEHHHHHH
YLKLQSRGSIIKFITKSDIEDIKIVLPNLKTYAKWNNVLKMIENNMQSTQTLTALRDFLL
HEEECCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLLKQQVKPQ
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6304321 [H]