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The map label for this gene is pgsA [H]

Identifier: 188527239

GI number: 188527239

Start: 424632

End: 425171

Strand: Reverse

Name: pgsA [H]

Synonym: HPSH_02230

Alternate gene names: 188527239

Gene position: 425171-424632 (Counterclockwise)

Preceding gene: 188527240

Following gene: 188527238

Centisome position: 26.43

GC content: 36.11

Gene sequence:

>540_bases
ATGAAAATTTTAAAACTCCTGCCTAATTTTTTAACGATTTTACGCATTGTCTTATCCTTATTTTTATTATTTTTATTGTT
AAACACGCGCACTTATTTTAGTTTTTTAACCCCCTTTCACATCAACATGATCTCTTCATTGGTTTTTTTATTTGCCGCGC
TCACAGATTTATTGGACGGCTACATCGCTAGAAGCTATAAAGCCAAATCGCGCTTTGGGGAAATCTTTGATCCTTTAGCG
GATAAAATCCTTATTTTGAGCGCGTTTTTAGGGTTAGTCCATTTGGATCGTGTGAACGCGTGGATTCCGTTTGTGATTTT
AGGGCGTGAATTTTTTATTTCAGGGCTTAGGGTTTTAGCCGCTAATGAAAAAAAGGATATTCCTGTCAATGCGCTAGGCA
AGTATAAAACCGTTTCTCAAGTCGTGGCGATTAGCGCTTTATTGGCTGATGTAACTTACTCTTATACGCTTGTGGCTATA
GCGGTTTTTTTAACCCTTTATTCGGGGATAGATTACACTATTAAATATTATAAATCTTAA

Upstream 100 bases:

>100_bases
TAGTTATCCTTTTTTTAACGATCGCTGTGATTTTAATGTGTGTGGCGCTTGGCTTTTTAGGGCGCGCGTTTTTGAATTTT
TCACAAGTCTTTTTGAAAGC

Downstream 100 bases:

>100_bases
TGTTTTAGAAGAAGTTTTTAGCGTTCTTTAAAAAATACCTTAAAACTCCGTTCTCATCCAATATTGATAAACATTAACCT
TAATTCTTTCGTTTTTTTTA

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKILKLLPNFLTILRIVLSLFLLFLLLNTRTYFSFLTPFHINMISSLVFLFAALTDLLDGYIARSYKAKSRFGEIFDPLA
DKILILSAFLGLVHLDRVNAWIPFVILGREFFISGLRVLAANEKKDIPVNALGKYKTVSQVVAISALLADVTYSYTLVAI
AVFLTLYSGIDYTIKYYKS

Sequences:

>Translated_179_residues
MKILKLLPNFLTILRIVLSLFLLFLLLNTRTYFSFLTPFHINMISSLVFLFAALTDLLDGYIARSYKAKSRFGEIFDPLA
DKILILSAFLGLVHLDRVNAWIPFVILGREFFISGLRVLAANEKKDIPVNALGKYKTVSQVVAISALLADVTYSYTLVAI
AVFLTLYSGIDYTIKYYKS
>Mature_179_residues
MKILKLLPNFLTILRIVLSLFLLFLLLNTRTYFSFLTPFHINMISSLVFLFAALTDLLDGYIARSYKAKSRFGEIFDPLA
DKILILSAFLGLVHLDRVNAWIPFVILGREFFISGLRVLAANEKKDIPVNALGKYKTVSQVVAISALLADVTYSYTLVAI
AVFLTLYSGIDYTIKYYKS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20245; Mature: 20245

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILKLLPNFLTILRIVLSLFLLFLLLNTRTYFSFLTPFHINMISSLVFLFAALTDLLDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIARSYKAKSRFGEIFDPLADKILILSAFLGLVHLDRVNAWIPFVILGREFFISGLRVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANEKKDIPVNALGKYKTVSQVVAISALLADVTYSYTLVAIAVFLTLYSGIDYTIKYYKS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECC
>Mature Secondary Structure
MKILKLLPNFLTILRIVLSLFLLFLLLNTRTYFSFLTPFHINMISSLVFLFAALTDLLDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIARSYKAKSRFGEIFDPLADKILILSAFLGLVHLDRVNAWIPFVILGREFFISGLRVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANEKKDIPVNALGKYKTVSQVVAISALLADVTYSYTLVAIAVFLTLYSGIDYTIKYYKS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA