BacMap

Definition	Helicobacter pylori Shi470, complete genome.
Accession	NC_010698
Length	1,608,548

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The map label for this gene is dnaJ2 [H]

Identifier: 188527232

GI number: 188527232

Start: 415942

End: 416808

Strand: Reverse

Name: dnaJ2 [H]

Synonym: HPSH_02195

Alternate gene names: 188527232

Gene position: 416808-415942 (Counterclockwise)

Preceding gene: 188527234

Following gene: 188527231

Centisome position: 25.91

GC content: 39.22

Gene sequence:

>867_bases
ATGAGCAAGAGTTTATACCAAACTTTAAATGTGAGCGAAAACGCCAACCAAGATGAAATCAAAAAATCCTACCGCCGTTT
AGCCAGACAATACCACCCGGATTTGAATAAAACCAAAGAAGCCGAAGAAAAATTCAAAGAAATCAACGCCGCTTATGAAA
TTTTAAGCGACGAAGAAAAACGCCGCCAATACGATCAGTTTGGCGATAACATGTTTGGCGGGCAGAATTTCAGCGATTTT
GCCAGAAGCCGCAGCGCTAGTGAAGATTTAGACGATATTTTAAGCTCTATTTTTGGGAGAGGAGGCTTTTCGCAAAGATT
TTCTCAAAATTCGCAAGGCTTTTCTGGCTTTAATTTTTCCAATTTCGCCCATGAAGATTTAGACATGACCACCACTTTAA
ATGTTTCTGTTTTAGACACCCTTTTAGGCAATAAAAAACAAGTGAGCGTCAATAATGAGACTTTTAGCCTTAAAATCCCT
ATCGGCGTGGAAGAGGGTGAAAAAATCAGGGTTCGCAACAAGGGGAAAATGGGGCGAACGGGCAAGGGCGATTTGCTCTT
GCAGATCCATATTGAAGAAGATGAAATTTATAAGCGCGAGAAAGACGATATTATCCAAATCTTTGATTTACCCTTAAAAA
CGGCTCTTTTTGGAGGGAAAATTGAAATCGCTACTTGGCATAAAACCTTAACCCTAACCATTCCCCCTAACACAAAAGCG
ATGCAAAAATTCCGCATTAAAGATAAAGGGATCAAAAACAGAAAAACTTCGCATGTGGGGGATTTGTATTTGCAAGCTCG
TTTGATTTTGCCTAAAACTGAAACGCTTTCTAGCGAGTTAAAAGCGTTATTAGAAAAAGAATTGTAA

Upstream 100 bases:

>100_bases
TTTAAAATCTCCATTACCTAAAAGCATTATCAATAAACTTGATTGACTAACACTAAAGATTTATGATAGTATTCTAATAA
AACTATTTTAAAGGTGATCC

Downstream 100 bases:

>100_bases
GGAGGAATCGTGTGCGATTATGATGAACCGCTTTATTTGATAAGCGTTGTGGCTAAAATCTTAGGCGTGCACCCTCAAAC
CTTGCGCCAATACGAAAAAG

Product: co-chaperone-curved DNA binding protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSKSLYQTLNVSENANQDEIKKSYRRLARQYHPDLNKTKEAEEKFKEINAAYEILSDEEKRRQYDQFGDNMFGGQNFSDF
ARSRSASEDLDDILSSIFGRGGFSQRFSQNSQGFSGFNFSNFAHEDLDMTTTLNVSVLDTLLGNKKQVSVNNETFSLKIP
IGVEEGEKIRVRNKGKMGRTGKGDLLLQIHIEEDEIYKREKDDIIQIFDLPLKTALFGGKIEIATWHKTLTLTIPPNTKA
MQKFRIKDKGIKNRKTSHVGDLYLQARLILPKTETLSSELKALLEKEL

Sequences:

>Translated_288_residues
MSKSLYQTLNVSENANQDEIKKSYRRLARQYHPDLNKTKEAEEKFKEINAAYEILSDEEKRRQYDQFGDNMFGGQNFSDF
ARSRSASEDLDDILSSIFGRGGFSQRFSQNSQGFSGFNFSNFAHEDLDMTTTLNVSVLDTLLGNKKQVSVNNETFSLKIP
IGVEEGEKIRVRNKGKMGRTGKGDLLLQIHIEEDEIYKREKDDIIQIFDLPLKTALFGGKIEIATWHKTLTLTIPPNTKA
MQKFRIKDKGIKNRKTSHVGDLYLQARLILPKTETLSSELKALLEKEL
>Mature_287_residues
SKSLYQTLNVSENANQDEIKKSYRRLARQYHPDLNKTKEAEEKFKEINAAYEILSDEEKRRQYDQFGDNMFGGQNFSDFA
RSRSASEDLDDILSSIFGRGGFSQRFSQNSQGFSGFNFSNFAHEDLDMTTTLNVSVLDTLLGNKKQVSVNNETFSLKIPI
GVEEGEKIRVRNKGKMGRTGKGDLLLQIHIEEDEIYKREKDDIIQIFDLPLKTALFGGKIEIATWHKTLTLTIPPNTKAM
QKFRIKDKGIKNRKTSHVGDLYLQARLILPKTETLSSELKALLEKEL

Specific function: Does not influence ATP binding or hydrolysis nor ADP release. Exerts influence on the interaction of dnaK with substrates; in the presence of dafA, dnaJ inhibits substrate binding, and substrate already bound to dnaK is displaced by dnaJ and dafA [H]

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=342, Percent_Identity=27.4853801169591, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI205360840, Length=342, Percent_Identity=27.4853801169591, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI5453690, Length=350, Percent_Identity=28.2857142857143, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI6631085, Length=336, Percent_Identity=26.7857142857143, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI56549115, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI201862518, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI201862587, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI194306642, Length=106, Percent_Identity=44.3396226415094, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI194306640, Length=106, Percent_Identity=44.3396226415094, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI56687498, Length=71, Percent_Identity=56.3380281690141, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI39204547, Length=317, Percent_Identity=23.0283911671924, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI9558755, Length=96, Percent_Identity=42.7083333333333, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI72534740, Length=121, Percent_Identity=36.3636363636364, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7706495, Length=329, Percent_Identity=27.0516717325228, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI45504382, Length=108, Percent_Identity=40.7407407407407, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI5031741, Length=93, Percent_Identity=41.9354838709677, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4504511, Length=103, Percent_Identity=41.747572815534, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI194328760, Length=170, Percent_Identity=31.1764705882353, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI194328758, Length=170, Percent_Identity=31.1764705882353, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI88501736, Length=67, Percent_Identity=52.2388059701493, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27151736, Length=67, Percent_Identity=55.2238805970149, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI47777312, Length=101, Percent_Identity=38.6138613861386, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI21553335, Length=112, Percent_Identity=38.3928571428571, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI29126218, Length=79, Percent_Identity=44.3037974683544, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22749377, Length=68, Percent_Identity=42.6470588235294, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17388799, Length=64, Percent_Identity=48.4375, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI23503241, Length=65, Percent_Identity=49.2307692307692, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4885495, Length=64, Percent_Identity=48.4375, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI68077168, Length=74, Percent_Identity=43.2432432432432, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI68077166, Length=74, Percent_Identity=43.2432432432432, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787235, Length=289, Percent_Identity=33.2179930795848, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786197, Length=273, Percent_Identity=26.3736263736264, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17534355, Length=321, Percent_Identity=29.9065420560748, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17553098, Length=347, Percent_Identity=26.5129682997118, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17553096, Length=347, Percent_Identity=26.5129682997118, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI212645553, Length=323, Percent_Identity=27.2445820433437, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563890, Length=65, Percent_Identity=56.9230769230769, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538236, Length=117, Percent_Identity=35.8974358974359, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17568643, Length=67, Percent_Identity=52.2388059701493, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554644, Length=67, Percent_Identity=49.2537313432836, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507263, Length=61, Percent_Identity=49.1803278688525, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115532476, Length=63, Percent_Identity=46.031746031746, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554874, Length=80, Percent_Identity=40, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324265, Length=102, Percent_Identity=48.0392156862745, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324252, Length=66, Percent_Identity=54.5454545454545, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323870, Length=68, Percent_Identity=45.5882352941176, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323119, Length=70, Percent_Identity=50, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324321, Length=64, Percent_Identity=54.6875, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323813, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24658562, Length=335, Percent_Identity=27.1641791044776, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24658555, Length=335, Percent_Identity=27.1641791044776, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI85726398, Length=358, Percent_Identity=28.7709497206704, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920464, Length=325, Percent_Identity=28.3076923076923, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI20129487, Length=342, Percent_Identity=27.4853801169591, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584014, Length=342, Percent_Identity=27.4853801169591, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549272, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45552813, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45552811, Length=69, Percent_Identity=53.6231884057971, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24654066, Length=92, Percent_Identity=45.6521739130435, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654070, Length=92, Percent_Identity=45.6521739130435, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654068, Length=92, Percent_Identity=45.6521739130435, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654072, Length=92, Percent_Identity=45.6521739130435, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=49.2753623188406, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI18858081, Length=276, Percent_Identity=25.3623188405797, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646562, Length=77, Percent_Identity=49.3506493506493, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646560, Length=77, Percent_Identity=49.3506493506493, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646558, Length=77, Percent_Identity=49.3506493506493, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646556, Length=77, Percent_Identity=49.3506493506493, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357547, Length=77, Percent_Identity=49.3506493506493, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737735, Length=66, Percent_Identity=51.5151515151515, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668523, Length=66, Percent_Identity=51.5151515151515, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574723, Length=66, Percent_Identity=51.5151515151515, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358273, Length=69, Percent_Identity=47.8260869565217, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859921, Length=71, Percent_Identity=47.887323943662, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161077138, Length=62, Percent_Identity=50, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24762799, Length=132, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641698, Length=65, Percent_Identity=43.0769230769231, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641696, Length=65, Percent_Identity=43.0769230769231, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 32955; Mature: 32824

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSLYQTLNVSENANQDEIKKSYRRLARQYHPDLNKTKEAEEKFKEINAAYEILSDEEK
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
RRQYDQFGDNMFGGQNFSDFARSRSASEDLDDILSSIFGRGGFSQRFSQNSQGFSGFNFS
HHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCC
NFAHEDLDMTTTLNVSVLDTLLGNKKQVSVNNETFSLKIPIGVEEGEKIRVRNKGKMGRT
CCCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCEEEEEEEEECCCCCEEEEECCCCCCCC
GKGDLLLQIHIEEDEIYKREKDDIIQIFDLPLKTALFGGKIEIATWHKTLTLTIPPNTKA
CCCCEEEEEEECHHHHHHCCCCCEEEHHCCCHHHHHCCCEEEEEEEEEEEEEEECCCHHH
MQKFRIKDKGIKNRKTSHVGDLYLQARLILPKTETLSSELKALLEKEL
HHHHHHHCCCCCCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKSLYQTLNVSENANQDEIKKSYRRLARQYHPDLNKTKEAEEKFKEINAAYEILSDEEK
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHH
RRQYDQFGDNMFGGQNFSDFARSRSASEDLDDILSSIFGRGGFSQRFSQNSQGFSGFNFS
HHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCC
NFAHEDLDMTTTLNVSVLDTLLGNKKQVSVNNETFSLKIPIGVEEGEKIRVRNKGKMGRT
CCCCCCCCCEEEEHHHHHHHHHCCCEEEEECCCEEEEEEEEECCCCCEEEEECCCCCCCC
GKGDLLLQIHIEEDEIYKREKDDIIQIFDLPLKTALFGGKIEIATWHKTLTLTIPPNTKA
CCCCEEEEEEECHHHHHHCCCCCEEEHHCCCHHHHHCCCEEEEEEEEEEEEEEECCCHHH
MQKFRIKDKGIKNRKTSHVGDLYLQARLILPKTETLSSELKALLEKEL
HHHHHHHCCCCCCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9349721; 9276481; 10092456 [H]