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The map label for this gene is fur [H]

Identifier: 188527229

GI number: 188527229

Start: 413777

End: 414229

Strand: Reverse

Name: fur [H]

Synonym: HPSH_02180

Alternate gene names: 188527229

Gene position: 414229-413777 (Counterclockwise)

Preceding gene: 188527230

Following gene: 188527215

Centisome position: 25.75

GC content: 38.19

Gene sequence:

>453_bases
ATGAAAAGATTAGAAACTTTAGAATCCATTTTAGAGCGCTTGAGAATGTCTATCAAAAAAAACGGACTCAAAAATTCAAA
ACAAAGAGAAGAAGTGGTGAGCGTTTTGTATCGCAGCGGCACACACCTAAGCCCTGAAGAAATCACGCATTCTATCCGCC
AAAAGGACAAAAACACCAGCATTTCTTCAGTCTATCGCATTTTGAATTTCTTAGAAAAAGAAAATTTTATCTGTGTTTTA
GAGACTTCAAAAAGCGGCCGGCGCTATGAAATTGCGGCTAAAGAACACCATGATCACATCATTTGTTTGCATTGCGGTAA
GATCATTGAATTTGCAGACCCTGAAATTGAACACCGCCAGAATGAAGTCGTTAAAAAATATCAAGCCAAGCTGATTAGCC
ATGACATGAAAATGTTTGTGTGGTGTAAAGAATGCCAAGAGAGCGCGTATTAA

Upstream 100 bases:

>100_bases
ATTAAAATAATAATGAGTTTTATCTATGTTTCATCGCATTATTATTGTATAATAATATTCTAGTTATAAAAATCATTTTA
CGGATAAGGAAAATATTAGC

Downstream 100 bases:

>100_bases
AAGATTTTAAAAAAGAAGCTTAGATAGGGCGGCTATCTTTAATGGTTTTAAGGACTTCATTCAAGTCAAAACGCTTGAGT
TTTAGATTTTTGATTTCTTC

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQNEVVKKYQAKLISHDMKMFVWCKECQESAY

Sequences:

>Translated_150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQNEVVKKYQAKLISHDMKMFVWCKECQESAY
>Mature_150_residues
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTSISSVYRILNFLEKENFICVL
ETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQNEVVKKYQAKLISHDMKMFVWCKECQESAY

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=137, Percent_Identity=31.3868613138686, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17707; Mature: 17707

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQ
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEEEECCCHHHHCCCHHHHHH
NEVVKKYQAKLISHDMKMFVWCKECQESAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRLETLESILERLRMSIKKNGLKNSKQREEVVSVLYRSGTHLSPEEITHSIRQKDKNTS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ISSVYRILNFLEKENFICVLETSKSGRRYEIAAKEHHDHIICLHCGKIIEFADPEIEHRQ
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCEEEEECCCHHHHCCCHHHHHH
NEVVKKYQAKLISHDMKMFVWCKECQESAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]