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The map label for this gene is cdsA [H]

Identifier: 188527019

GI number: 188527019

Start: 208844

End: 209644

Strand: Direct

Name: cdsA [H]

Synonym: HPSH_01110

Alternate gene names: 188527019

Gene position: 208844-209644 (Clockwise)

Preceding gene: 188527018

Following gene: 188527020

Centisome position: 12.98

GC content: 43.32

Gene sequence:

>801_bases
GTGAAAGAAGAGTTATTTAAAGAAAAATCTCGCTACATTACAGGGTTTGTTTTAATCATTGTGGCAGGCTTGATTTTGTA
TGCGGACAATTTGTTGTTGTTTTGGGCGGTTTTAGGGGGGATTTATGTGGTAGGGTTTTCTGAAGCGTTAAGACTATTTC
AAGTTAAAGCGAGCTTTAGTTTGTATCTTATTTTAGTGTTGTCATGGGTAGTGGCGTATTTTAACGGGCACCCTATAGAA
TGCGCTCTTATTAGTGCGATGGTCATGGCTAGCATCATCGCTTATCAAAAAGCGCACCATAGCGAAGCCATTTTACCCTT
TTTATACCCGGGAGTTGGGTTTTTTGCGCTTTTTGGGGTTTATAAGGATTTTGGTGCAGTAGCGATCATTTGGCTTTTAG
TCGTGGTGGTTGCAAGCGATGTGGGGGCGTTTTTTGGAGGCAAGCTTTTAGGAAAAACCCCTTTCACGCCCACTTCGCCA
AATAAAACCTTAGAGGGCGCGTTGATTGGCGTGGTTTTGGCGAGCGTTTTAGGATCGTTTGTGGGCATGGGGAAATTGAG
CGGGGGCTTTTTTATGGCGCTTTTATTCAGCTTTTTAATCGCTCTTGTGGCGGTGTTTGGGGATTTGTATGAAAGCTATT
TGAAACGAAAGGCCGGGATCAAAGATAGCGGTAAGATTTTACCCGGGCATGGGGGCGTTTTAGACCGATTGGATTCCATG
CTTTTTGGGGCTTTAGGCTTGCATGTGTTGTTGTATTTTTTAGAAATTTGGAAAGAAACGGCGGTGTTTTTAGGGGATTG
A

Upstream 100 bases:

>100_bases
GATTAAAGCCGGTTTGTGGCTTAATTTAGTGGGAGTTGTTTTGATTAGCGCGTTTAGCTATTTTTTAGTTTCGCTGGTAT
TTAATTGATCAAGGAAAAAA

Downstream 100 bases:

>100_bases
ATGGTTGTTTTAGGAAGCACCGGCTCTATTGGGAAAAACGCCCTAAAAATCGCAAAAAAATTCAAGGTAGGAATAGAAGC
CTTAAGCTGTGGGAAAAATA

Product: CDP-diglyceride synthetase (cdsA)

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKEELFKEKSRYITGFVLIIVAGLILYADNLLLFWAVLGGIYVVGFSEALRLFQVKASFSLYLILVLSWVVAYFNGHPIE
CALISAMVMASIIAYQKAHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALVAVFGDLYESYLKRKAGIKDSGKILPGHGGVLDRLDSM
LFGALGLHVLLYFLEIWKETAVFLGD

Sequences:

>Translated_266_residues
MKEELFKEKSRYITGFVLIIVAGLILYADNLLLFWAVLGGIYVVGFSEALRLFQVKASFSLYLILVLSWVVAYFNGHPIE
CALISAMVMASIIAYQKAHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALVAVFGDLYESYLKRKAGIKDSGKILPGHGGVLDRLDSM
LFGALGLHVLLYFLEIWKETAVFLGD
>Mature_266_residues
MKEELFKEKSRYITGFVLIIVAGLILYADNLLLFWAVLGGIYVVGFSEALRLFQVKASFSLYLILVLSWVVAYFNGHPIE
CALISAMVMASIIAYQKAHHSEAILPFLYPGVGFFALFGVYKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSP
NKTLEGALIGVVLASVLGSFVGMGKLSGGFFMALLFSFLIALVAVFGDLYESYLKRKAGIKDSGKILPGHGGVLDRLDSM
LFGALGLHVLLYFLEIWKETAVFLGD

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=144, Percent_Identity=40.9722222222222, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787677, Length=119, Percent_Identity=39.4957983193277, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 28859; Mature: 28859

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEELFKEKSRYITGFVLIIVAGLILYADNLLLFWAVLGGIYVVGFSEALRLFQVKASFS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYLILVLSWVVAYFNGHPIECALISAMVMASIIAYQKAHHSEAILPFLYPGVGFFALFGV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YKDFGAVAIIWLLVVVVASDVGAFFGGKLLGKTPFTPTSPNKTLEGALIGVVLASVLGSF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VGMGKLSGGFFMALLFSFLIALVAVFGDLYESYLKRKAGIKDSGKILPGHGGVLDRLDSM
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LFGALGLHVLLYFLEIWKETAVFLGD
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]