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The map label for this gene is mrp [H]

Identifier: 188527010

GI number: 188527010

Start: 197050

End: 198156

Strand: Direct

Name: mrp [H]

Synonym: HPSH_01065

Alternate gene names: 188527010

Gene position: 197050-198156 (Clockwise)

Preceding gene: 188527008

Following gene: 188527013

Centisome position: 12.25

GC content: 44.08

Gene sequence:

>1107_bases
ATGCTCACCCAAGAAGATGTCTTAAACGCGTTAAAAACGATCATCTACCCTAATTTTGAAAAGGATATTGTCAGCTTTGG
TTTTGTCAAAAACATCGCTTTGCATGACAACCAATTAGGGCTTTTAATAGAAATCCCCTCAAGCTCTGAAGAAACGAGTG
CGATTTTAAGGGAAAATATCTCCAAAGCGATGCAAAAAATGGGCGTGAAAGCTTTGAATTTGGATATTAAAACCCCGCCT
AAACCGCAAGCCCCAAAGCCCACCACTAAAAATCTGGCTAAAAATATCAAGCATGTAGTGATGATAAGCTCGGGTAAGGG
CGGTGTGGGCAAAAGCACCACCAGCGTGAATTTAAGCATCGCTCTAGCGAATTTAAACCAAAAAGTGGGGTTACTAGACG
CTGATGTGTATGGCCCTAATATCCCTAGAATGATGGGCTTGCAAAACGCTGATGTGATCATGGATCCTAGCGGTAAGAAA
CTCATTCCTTTAAAAGCTTTTGGCGTTTCTGTGATGAGCATGGGGCTTTTGTATGATGAGGGGCAGAGTCTCATTTGGAG
AGGGCCCATGCTCATGCGAGCGATTGAGCAGATGCTAAGCGATATTATTTGGGGGGATTTAGATGTTTTGGTGGTGGATA
TGCCACCAGGAACAGGCGATGCGCAACTCACGCTAGCCCAAGCTGTGCCTTTGAGTGCAGGAATTACTGTTACTACGCCT
CAAATCGTGAGTTTGGATGACGCTAAACGGAGTTTGGACATGTTTAAGAAACTACACATTCCTATTGCGGGCATTGTAGA
AAATATGGGGAGTTTTGTGTGCGAGCATTGCAAGAAAGAGAGTGAGATTTTTGGCTCAAATTCCATGAATGAGTTGCTAG
AAGCTTACCACACGCAGATTTTAGCCAAGCTCCCTTTAGAGCCTAAAGTGCGTTTAGGGGGGGATAGGGGCGAACCGATT
GTGATCTCTCACCCTAATAGCGTGAGCGCTAAGATTTTTGAAAAAATGGCGCAAGATTTGAGCGCTTTTTTAGACAAAGT
AAAAAAGGAAAAACTAGCCGATAACAAGGACATCCAGCCCACACAAACCCATGCTTGCTCGCATTAG

Upstream 100 bases:

>100_bases
TGCCTTACCCTTTTTTAAAAACTTAAACTTAATTTATAATGCAAAATTAAACAAAACATGCTATAAAGAAAATTCAAATA
CTATCATTTTAAGGATTAAA

Downstream 100 bases:

>100_bases
TTTTGAAAGGGTTTTTTAAACCCTTTTAATCAATCGCTTCACTTTTTGTTTGGCTTTAAAAAGCAAAAATTCTATAAGGA
GTTTAGAAGAAAACCTGGGA

Product: ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNIALHDNQLGLLIEIPSSSEETSAILRENISKAMQKMGVKALNLDIKTPP
KPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSIALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKK
LIPLKAFGVSVMSMGLLYDEGQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTP
QIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMNELLEAYHTQILAKLPLEPKVRLGGDRGEPI
VISHPNSVSAKIFEKMAQDLSAFLDKVKKEKLADNKDIQPTQTHACSH

Sequences:

>Translated_368_residues
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNIALHDNQLGLLIEIPSSSEETSAILRENISKAMQKMGVKALNLDIKTPP
KPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSIALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKK
LIPLKAFGVSVMSMGLLYDEGQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTP
QIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMNELLEAYHTQILAKLPLEPKVRLGGDRGEPI
VISHPNSVSAKIFEKMAQDLSAFLDKVKKEKLADNKDIQPTQTHACSH
>Mature_368_residues
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNIALHDNQLGLLIEIPSSSEETSAILRENISKAMQKMGVKALNLDIKTPP
KPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSIALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKK
LIPLKAFGVSVMSMGLLYDEGQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTP
QIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMNELLEAYHTQILAKLPLEPKVRLGGDRGEPI
VISHPNSVSAKIFEKMAQDLSAFLDKVKKEKLADNKDIQPTQTHACSH

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=249, Percent_Identity=42.9718875502008, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI118572611, Length=275, Percent_Identity=37.8181818181818, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI6912540, Length=256, Percent_Identity=38.28125, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI87082045, Length=341, Percent_Identity=38.7096774193548, Blast_Score=246, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI25143050, Length=273, Percent_Identity=37.7289377289377, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322188, Length=222, Percent_Identity=41.8918918918919, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321347, Length=256, Percent_Identity=35.546875, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI221511043, Length=260, Percent_Identity=37.3076923076923, Blast_Score=204, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24667611, Length=256, Percent_Identity=38.671875, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19921440, Length=236, Percent_Identity=38.135593220339, Blast_Score=141, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR002744
- InterPro:   IPR000808
- InterPro:   IPR000392 [H]

Pfam domain/function: PF01883 DUF59; PF00142 Fer4_NifH; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 40011; Mature: 40011

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNIALHDNQLGLLIEIPSSSEETSAILRENI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHH
SKAMQKMGVKALNLDIKTPPKPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSI
HHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEE
ALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKKLIPLKAFGVSVMSMGLLYDE
EEECCCCCCCEEECCCCCCCCCHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHEEC
GQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTP
CCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEECCC
QIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMNELLEAYHTQI
CEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAKLPLEPKVRLGGDRGEPIVISHPNSVSAKIFEKMAQDLSAFLDKVKKEKLADNKDIQP
HHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TQTHACSH
CCCCCCCC
>Mature Secondary Structure
MLTQEDVLNALKTIIYPNFEKDIVSFGFVKNIALHDNQLGLLIEIPSSSEETSAILRENI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCEEEEEECCCCCHHHHHHHHHHH
SKAMQKMGVKALNLDIKTPPKPQAPKPTTKNLAKNIKHVVMISSGKGGVGKSTTSVNLSI
HHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEE
ALANLNQKVGLLDADVYGPNIPRMMGLQNADVIMDPSGKKLIPLKAFGVSVMSMGLLYDE
EEECCCCCCCEEECCCCCCCCCHHHCCCCCCEEECCCCCEEEEHHHHHHHHHHHHHHEEC
GQSLIWRGPMLMRAIEQMLSDIIWGDLDVLVVDMPPGTGDAQLTLAQAVPLSAGITVTTP
CCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCCEEECCC
QIVSLDDAKRSLDMFKKLHIPIAGIVENMGSFVCEHCKKESEIFGSNSMNELLEAYHTQI
CEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAKLPLEPKVRLGGDRGEPIVISHPNSVSAKIFEKMAQDLSAFLDKVKKEKLADNKDIQP
HHHCCCCCCEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TQTHACSH
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]