Click here to switch to the map view.

The map label for this gene is aroK

Identifier: 188526962

GI number: 188526962

Start: 151149

End: 151637

Strand: Direct

Name: aroK

Synonym: HPSH_00795

Alternate gene names: 188526962

Gene position: 151149-151637 (Clockwise)

Preceding gene: 188526961

Following gene: 188526963

Centisome position: 9.4

GC content: 39.06

Gene sequence:

>489_bases
ATGCGGCATTTGGTTTTAATCGGTTTTATGGGGAGCGGTAAAAGCTCCTTAGCGCAAGAATTGGGGTTGGCTTTGAAATT
AGAAGTGTTGGATACGGATATGATCATTAGCGAGAGGGTGGGCTTGAGCGTGAGAGGGATTTTTGAAGAGCTTGGCGAAG
ACAATTTCAGGATGTTTGAAAAAAATTTGATTGATGAATTAAAAACGCTCAAAACCCCCCATATTATTTCTACCGGTGGG
GGCATTGTGATGCATGATAACCTTAAGGGTTTAGGCACAACTTTTTATCTCAAAATGGATTTTGAGACCTTGATTAAGCG
TTTGAATCAAAAAGAAAGGGAAAAACGCCCCCTTTTGAATGATCTCACTCAAGCCAAAGAGCTTTTTGAAAAACGCCAAG
TCCTCTATGAAAAAAACGCCTCTTTTATCATTGATGCAAGGGGTGGTTTAAATAATTCTTTAAAACAAGTGCTACAATTC
ATCGCATAA

Upstream 100 bases:

>100_bases
CACAAAGATTATTACCGCATCACGCTCATTTTAGACGGGAAATACCGCTATCTTTTGGAAGAAAAAAACGGGGCGTATGA
ATTAAAATTGGAATAAAAGC

Downstream 100 bases:

>100_bases
TTTTTTTTAAAGGCCTTTTGATGTTGAGTAGAGACATTGTCCAATATTCCAAGATTCGCACCGAGCTATACGCTTATCTT
ACCTATTTGTTTTCGCACAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKTLKTPHIISTGG
GIVMHDNLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNDLTQAKELFEKRQVLYEKNASFIIDARGGLNNSLKQVLQF
IA

Sequences:

>Translated_162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKTLKTPHIISTGG
GIVMHDNLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNDLTQAKELFEKRQVLYEKNASFIIDARGGLNNSLKQVLQF
IA
>Mature_162_residues
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKTLKTPHIISTGG
GIVMHDNLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLNDLTQAKELFEKRQVLYEKNASFIIDARGGLNNSLKQVLQF
IA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI87082255, Length=151, Percent_Identity=35.7615894039735, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_HELPS (B2URY7)

Other databases:

- EMBL:   CP001072
- RefSeq:   YP_001909649.1
- ProteinModelPortal:   B2URY7
- GeneID:   6296222
- GenomeReviews:   CP001072_GR
- KEGG:   hps:HPSH_00795
- HOGENOM:   HBG335815
- OMA:   MIISERV
- ProtClustDB:   PRK00131
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- InterPro:   IPR023000
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 18397; Mature: 18397

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 33-33 BINDING 57-57 BINDING 80-80 BINDING 116-116 BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFE
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKTLKTPHIISTGGGIVMHDNLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHH
DLTQAKELFEKRQVLYEKNASFIIDARGGLNNSLKQVLQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MRHLVLIGFMGSGKSSLAQELGLALKLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFE
CCEEEEEEECCCCHHHHHHHHCCEEEEEECCCHHHHHHHCCCHHHHHHHHHCCCHHHHHH
KNLIDELKTLKTPHIISTGGGIVMHDNLKGLGTTFYLKMDFETLIKRLNQKEREKRPLLN
HHHHHHHHHHCCCCEEECCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHCCHHH
DLTQAKELFEKRQVLYEKNASFIIDARGGLNNSLKQVLQFIA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA