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The map label for this gene is mcp4 [H]

Identifier: 188526908

GI number: 188526908

Start: 96130

End: 97827

Strand: Reverse

Name: mcp4 [H]

Synonym: HPSH_00515

Alternate gene names: 188526908

Gene position: 97827-96130 (Counterclockwise)

Preceding gene: 188526909

Following gene: 188526907

Centisome position: 6.08

GC content: 42.05

Gene sequence:

>1698_bases
ATGGTGTTTTCTTCAATGTTTGCTTCGTTAGGGACTCGTATCGTGCTGGTCGTGTTAGCCGCGCTTATTTCTTTAGGGGG
GCTTTTTATTGGTTTTGTAAAGGTTATGCAAAAAGATGCGTTAGCGCAACTCAAGGAGCATTTAGAAACCGAGCAATACA
AAAAGCGTGAAAAAACGCTCGCTTACATGACAAAACTTCTTGAACAGGGCATTCATGAGTATTACAAAAATTTTGACAAT
ACCACTGCAAGAAAAATGGCTTTGGATTATTTTAAACGCATTAACGACGATAAGGGCATGATTTATATGGTGGTGGTGGA
TAAAAACGGGATAGTCTTGTTTGATCCAGTCAATCCTAAAACCGTAGGCCAATCAGGGCTTGACGCTCAGAGCGTTGATG
GGGTGTATTATGTTAGGGGGTATTTGGAAGCGGCTAAAAAAGGGGGAGGCTACACTTATTATAAAATGCCTAAATACGAT
GGAGGCGTGCCGGAGAAAAAATTCGCCTATTCGCATTATGATGAGGTGTCTTCAATGGTGATCGCAACGACTTCTTATTA
CACTGACATTAACACAGAAAATAAAGCGATCACAGAAGGCGTGGACAAGGTTTTTAATGAAAGCGCCACGAAATTATTCC
TTTGGATACTGACAGCGACGATAGCGTTAGTGGTTTTGACGCTCATATACGCTAAATTAAGGATCGTGAAACGCATTGAC
GAACTGGTCCTTAAAATCAACGCTTTCAGCCATGGGGATAAGGATTTGAGGGCCAAAATTGATGTGGATGATCGCAACGA
TGAAATCTCGCAAGTGGGCCGTGGGGTCAATTTGTTTGTGGAAAACGCCCGCTTGATCATAGAAGAGATTAAAGGGATTT
CCACCCTCAATAAAACTTCAATGGGCAAATTAGTCCAAATCGCGCAAGAAACCCAAAAGAGCATGAAAAATTCATCAACC
ACCCTAAATTCCGTAAAAAATAAAGCCACTGGTATAGCGAGCATGATGAATGCTTCCATAGAGCAGTCTCAAGGGTTAAG
GAAGCACTTGATTGAAACGCAAGCGCTTGTCAAAGAGAGTAAGGATGCGATCGGGGATTTGTTTTCTCAAATCACAGAGA
GCGCGCACACTGAAGAGGAACTCTCTAGCAAAGTGGAGCAACTAAGCCGTAACGCTGATGATGTCAAATCCATTTTGGAT
ATTATCAATGATATTGCCGATCAAACCAATCTTTTAGCCCTAAACGCCGCTATTGAAGCCGCAAGAGCCGGCGAGCATGG
CAGAGGCTTTGCGGTAGTGGCTGATGAAGTTAGGAATTTAGCCGGGCGCACTCAAAAGTCTTTAGCCGAAATCAATTCCA
CTATCATGGTGATTGTCCAAGAAATCAATGCTGTAAGCTCGCAAATGAATCTCAATTCGCAAAAAATGGAGCGCTTGAGC
GATATGAGTAAAAGCGTGCAAGAAACTTACGACAAAATGAGTTCTAATTTAAGCTCAGTCGTGTCAGACAGCAATCAAAG
CATGGACGATTACGCCAAATCCGGACACCAAATTGAAGCTATGGTAAGCGATTTTGTGGAAGTGGAAAAAGTGGCTTCTA
AGACTTTAGCCGATTCTTCAGATATTTTAAACATCGCTACGCATGTGAGCGAAACGACCATGAATTTAGACAAACAAGTG
AATTTGTTTAAAACTTAA

Upstream 100 bases:

>100_bases
TTTAATTTTGTTTTGCATCCCTCATTTTTCGGGGGGGGGGCATTTAGAAGCTGAATTCTAAAATTAGGGTTTGACTTAAA
AATGATTGATTAGGAGATGA

Downstream 100 bases:

>100_bases
TCAGGAGGAGTTGATTAAAAAAGGGTTGGATTGTTAAAAGTTTCTGTGATCACGGCGTGTTTTAATAGCGAAAAAACCAT
TGAAGACACCATTCTTTCCG

Product: methyl-accepting chemotaxis protein (tlpB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MVFSSMFASLGTRIVLVVLAALISLGGLFIGFVKVMQKDALAQLKEHLETEQYKKREKTLAYMTKLLEQGIHEYYKNFDN
TTARKMALDYFKRINDDKGMIYMVVVDKNGIVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSSMVIATTSYYTDINTENKAITEGVDKVFNESATKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSHGDKDLRAKIDVDDRNDEISQVGRGVNLFVENARLIIEEIKGISTLNKTSMGKLVQIAQETQKSMKNSST
TLNSVKNKATGIASMMNASIEQSQGLRKHLIETQALVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYDKMSSNLSSVVSDSNQSMDDYAKSGHQIEAMVSDFVEVEKVASKTLADSSDILNIATHVSETTMNLDKQV
NLFKT

Sequences:

>Translated_565_residues
MVFSSMFASLGTRIVLVVLAALISLGGLFIGFVKVMQKDALAQLKEHLETEQYKKREKTLAYMTKLLEQGIHEYYKNFDN
TTARKMALDYFKRINDDKGMIYMVVVDKNGIVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSSMVIATTSYYTDINTENKAITEGVDKVFNESATKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSHGDKDLRAKIDVDDRNDEISQVGRGVNLFVENARLIIEEIKGISTLNKTSMGKLVQIAQETQKSMKNSST
TLNSVKNKATGIASMMNASIEQSQGLRKHLIETQALVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYDKMSSNLSSVVSDSNQSMDDYAKSGHQIEAMVSDFVEVEKVASKTLADSSDILNIATHVSETTMNLDKQV
NLFKT
>Mature_565_residues
MVFSSMFASLGTRIVLVVLAALISLGGLFIGFVKVMQKDALAQLKEHLETEQYKKREKTLAYMTKLLEQGIHEYYKNFDN
TTARKMALDYFKRINDDKGMIYMVVVDKNGIVLFDPVNPKTVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYD
GGVPEKKFAYSHYDEVSSMVIATTSYYTDINTENKAITEGVDKVFNESATKLFLWILTATIALVVLTLIYAKLRIVKRID
ELVLKINAFSHGDKDLRAKIDVDDRNDEISQVGRGVNLFVENARLIIEEIKGISTLNKTSMGKLVQIAQETQKSMKNSST
TLNSVKNKATGIASMMNASIEQSQGLRKHLIETQALVKESKDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILD
IINDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
DMSKSVQETYDKMSSNLSSVVSDSNQSMDDYAKSGHQIEAMVSDFVEVEKVASKTLADSSDILNIATHVSETTMNLDKQV
NLFKT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=178, Percent_Identity=34.2696629213483, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367378, Length=261, Percent_Identity=31.0344827586207, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788195, Length=205, Percent_Identity=35.1219512195122, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789453, Length=339, Percent_Identity=27.1386430678466, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787690, Length=168, Percent_Identity=34.5238095238095, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62629; Mature: 62629

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFSSMFASLGTRIVLVVLAALISLGGLFIGFVKVMQKDALAQLKEHLETEQYKKREKTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYMTKLLEQGIHEYYKNFDNTTARKMALDYFKRINDDKGMIYMVVVDKNGIVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYDGGVPEKKFAYSHYDEVSSMV
CCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IATTSYYTDINTENKAITEGVDKVFNESATKLFLWILTATIALVVLTLIYAKLRIVKRID
HEEHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVLKINAFSHGDKDLRAKIDVDDRNDEISQVGRGVNLFVENARLIIEEIKGISTLNKTS
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHH
MGKLVQIAQETQKSMKNSSTTLNSVKNKATGIASMMNASIEQSQGLRKHLIETQALVKES
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYDKMSSNLSSVVSDSNQSMDDYAKSGHQIEAMVSDFVEVEKVASKTLADSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCH
DILNIATHVSETTMNLDKQVNLFKT
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVFSSMFASLGTRIVLVVLAALISLGGLFIGFVKVMQKDALAQLKEHLETEQYKKREKTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYMTKLLEQGIHEYYKNFDNTTARKMALDYFKRINDDKGMIYMVVVDKNGIVLFDPVNPK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCC
TVGQSGLDAQSVDGVYYVRGYLEAAKKGGGYTYYKMPKYDGGVPEKKFAYSHYDEVSSMV
CCCCCCCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
IATTSYYTDINTENKAITEGVDKVFNESATKLFLWILTATIALVVLTLIYAKLRIVKRID
HEEHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELVLKINAFSHGDKDLRAKIDVDDRNDEISQVGRGVNLFVENARLIIEEIKGISTLNKTS
HHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHH
MGKLVQIAQETQKSMKNSSTTLNSVKNKATGIASMMNASIEQSQGLRKHLIETQALVKES
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDAIGDLFSQITESAHTEEELSSKVEQLSRNADDVKSILDIINDIADQTNLLALNAAIEA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
ARAGEHGRGFAVVADEVRNLAGRTQKSLAEINSTIMVIVQEINAVSSQMNLNSQKMERLS
HHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMSKSVQETYDKMSSNLSSVVSDSNQSMDDYAKSGHQIEAMVSDFVEVEKVASKTLADSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCH
DILNIATHVSETTMNLDKQVNLFKT
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]