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The map label for this gene is panC

Identifier: 188526818

GI number: 188526818

Start: 3198

End: 4028

Strand: Direct

Name: panC

Synonym: HPSH_00030

Alternate gene names: 188526818

Gene position: 3198-4028 (Clockwise)

Preceding gene: 188526817

Following gene: 188526822

Centisome position: 0.2

GC content: 41.52

Gene sequence:

>831_bases
ATGCGAGCGTTAGAAACGATTGCTACTTTAAGAGAATATCGTAAAAGTTTGAAAGAAAGCGTGGGGTTTGTGCCGACTAT
GGGAGCTTTACACAAAGGGCATCAAAGCTTGATAGAAAGGAGTTTGAAAGAAAATTCCCACACGATAGTGAGTGTTTTTG
TCAATCCCACGCAATTTGGGGCTAACGAAGATTTTAGCGCTTACCCTCGCCCTTTAGAAAAGGATTTGGCCTTGTGTGAA
GGATTGGGCGTTAATGCGGTGTTTGTGCCTAAAACGAGCGAAATGTATCCCTATGAAATAGAGAAACGCTTAAAACTCTA
CGCCCCTACATTTTTATCCCACTCTTTAGAGGGAGCAATGCGTGAGGGGCATTTTGATGGGGTTGTTCAGGTTGTGTTAA
GATTGTTCCATCTTGTTAATCCCACTAGAGCGTATTTTGGTAAAAAGGACGCCCAACAGCTTTTAATCATCCAGCATTTA
GTCCAAGATTTGCTTTTAGACATTGAAATAGCGCCATGCGAGATCGTGCGCGATAGCGATAATTTGGCTTTAAGCTCTAG
GAATGTGTATTTGAATGCAACACAAAGAAAACAAGCCCTAGCCATTCCAAAAGCTCTAGAAAACATCAAGCAAGCCATAG
ATAAGGGCGAAAAAGCGTGCGAAAAGCTTAAAAAACTAGGGCTTAAAATTTTAGAAACCTTGGAAGTGGATTATTTGGAA
TTTTGCAACCACAAGCTAGAGCCTTTAAAAACCATAGAGCCAACTAACACGCTGGTTTTAGTGGCGGCTCGTGTGGGTAA
AACTAGGCTTTTAGACAATTTATGGGTGTAG

Upstream 100 bases:

>100_bases
GGCCAAACAAAATTTAAGCGATTTTATCGTGGTGGGCCGCCCCATTTATCAGGCTAAAGAGCCTAGAGAAGTGGTTTTAG
AGCTTTTAAAGGATTGTTAA

Downstream 100 bases:

>100_bases
TTTGGAATTTTTGTGGCGACCCTTGAAAGATTTGAACTTCCGTTTCCACCGTGAAAGGGTGGTATCCTTGGCCACTAGAT
GAAAGGGTCATTTTTAACGA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRALETIATLREYRKSLKESVGFVPTMGALHKGHQSLIERSLKENSHTIVSVFVNPTQFGANEDFSAYPRPLEKDLALCE
GLGVNAVFVPKTSEMYPYEIEKRLKLYAPTFLSHSLEGAMREGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIQHL
VQDLLLDIEIAPCEIVRDSDNLALSSRNVYLNATQRKQALAIPKALENIKQAIDKGEKACEKLKKLGLKILETLEVDYLE
FCNHKLEPLKTIEPTNTLVLVAARVGKTRLLDNLWV

Sequences:

>Translated_276_residues
MRALETIATLREYRKSLKESVGFVPTMGALHKGHQSLIERSLKENSHTIVSVFVNPTQFGANEDFSAYPRPLEKDLALCE
GLGVNAVFVPKTSEMYPYEIEKRLKLYAPTFLSHSLEGAMREGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIQHL
VQDLLLDIEIAPCEIVRDSDNLALSSRNVYLNATQRKQALAIPKALENIKQAIDKGEKACEKLKKLGLKILETLEVDYLE
FCNHKLEPLKTIEPTNTLVLVAARVGKTRLLDNLWV
>Mature_276_residues
MRALETIATLREYRKSLKESVGFVPTMGALHKGHQSLIERSLKENSHTIVSVFVNPTQFGANEDFSAYPRPLEKDLALCE
GLGVNAVFVPKTSEMYPYEIEKRLKLYAPTFLSHSLEGAMREGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIQHL
VQDLLLDIEIAPCEIVRDSDNLALSSRNVYLNATQRKQALAIPKALENIKQAIDKGEKACEKLKKLGLKILETLEVDYLE
FCNHKLEPLKTIEPTNTLVLVAARVGKTRLLDNLWV

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=284, Percent_Identity=39.4366197183099, Blast_Score=178, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6322046, Length=270, Percent_Identity=38.1481481481481, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31162; Mature: 31162

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALETIATLREYRKSLKESVGFVPTMGALHKGHQSLIERSLKENSHTIVSVFVNPTQFG
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCC
ANEDFSAYPRPLEKDLALCEGLGVNAVFVPKTSEMYPYEIEKRLKLYAPTFLSHSLEGAM
CCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
REGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIQHLVQDLLLDIEIAPCEIVRDSD
HCCCHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCC
NLALSSRNVYLNATQRKQALAIPKALENIKQAIDKGEKACEKLKKLGLKILETLEVDYLE
CEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCNHKLEPLKTIEPTNTLVLVAARVGKTRLLDNLWV
HCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHCCC
>Mature Secondary Structure
MRALETIATLREYRKSLKESVGFVPTMGALHKGHQSLIERSLKENSHTIVSVFVNPTQFG
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCC
ANEDFSAYPRPLEKDLALCEGLGVNAVFVPKTSEMYPYEIEKRLKLYAPTFLSHSLEGAM
CCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
REGHFDGVVQVVLRLFHLVNPTRAYFGKKDAQQLLIIQHLVQDLLLDIEIAPCEIVRDSD
HCCCHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCC
NLALSSRNVYLNATQRKQALAIPKALENIKQAIDKGEKACEKLKKLGLKILETLEVDYLE
CEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCNHKLEPLKTIEPTNTLVLVAARVGKTRLLDNLWV
HCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA