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The map label for this gene is galU [H]

Identifier: 187935752

GI number: 187935752

Start: 3291053

End: 3291925

Strand: Reverse

Name: galU [H]

Synonym: CLL_A3172

Alternate gene names: 187935752

Gene position: 3291925-3291053 (Counterclockwise)

Preceding gene: 187933465

Following gene: 187933822

Centisome position: 86.62

GC content: 30.36

Gene sequence:

>873_bases
ATGAAAGTTAAAAAAGCCATTATTCCAGCAGCTGGACTAGGAACAAGATTTTTACCAGCAACTAAAGCGCAACCAAAGGA
AATGCTTCCTATAGTTGACAAACCAACAATTCAATACATAATTGAAGAGGCAGTTGCATCGGGAATAGAAGAAATACTTA
TTATAACAGGAAGAAATAAAAAGTGTATAGAAGATCATTTTGATAAATCTATAGAATTAGAATTTGAATTAGAAAAGTCA
GGAAAAGAAGAACTTTTAGAATTAGTAAGAAATATTTCTGATATGGTTGATATACATTATATTAGACAAAAAGAACCTAA
AGGATTAGGTCATGCAATTCATTGTGCAAAAACATTTGTGGGTAATGAACCTTTTGCAGTTTTATTAGGTGATGATGTTG
TTGACAGTGAAAAACCATGTTTAAAACAATTAATAGATTGTTTTAGTGAGTATAATACTACTATTTTAGGTGTTCAAACT
GTAGCACAAGAAAACGTATCAAAATACGGAATAGTTGATGGACTTCATATAGAAGATAGAGTCTATAAAGTAAAGGATTT
AGTTGAGAAGCCATCAGTAGAAGAAGCACCTAGTAATGTAGCTATTTTAGGGAGATATATTATAACACCTGAAATATTTA
ATATATTAGAAAACACAAAGCCAGGAAAAGGCGGAGAAATTCAACTAACTGACGCATTAAAAACTTTAATTAGTAAAGAA
GCAATGTATGCTTATAATTTTGAAGGCAGAAGATATGATGTAGGAGATAAACTTGGGTTTCTACAAGCAACAGTAGAATT
TGCATTAAAAAGAGAAGAATTAAGAGAGCCTTTTATAGAATATCTAAAAGGCAATCCATGGGATGAAAAATAA

Upstream 100 bases:

>100_bases
ACACTTTGGTAAATATGTGATAACATAAGAATAGTTGAAATTACAAGCAAAAACTTTATTTAAAGTTAAAAATATAACTT
TATGAGAGGAAGATATAAAA

Downstream 100 bases:

>100_bases
AATTAATTTAAGATATCAACATTTGCTTAAAACAAAAAGCTATGATTTAAAAATCATAGCTTTTTGTTTTAAAAACTTTA
TCTTGGAATGAATCCAACTT

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKVKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAVASGIEEILIITGRNKKCIEDHFDKSIELEFELEKS
GKEELLELVRNISDMVDIHYIRQKEPKGLGHAIHCAKTFVGNEPFAVLLGDDVVDSEKPCLKQLIDCFSEYNTTILGVQT
VAQENVSKYGIVDGLHIEDRVYKVKDLVEKPSVEEAPSNVAILGRYIITPEIFNILENTKPGKGGEIQLTDALKTLISKE
AMYAYNFEGRRYDVGDKLGFLQATVEFALKREELREPFIEYLKGNPWDEK

Sequences:

>Translated_290_residues
MKVKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAVASGIEEILIITGRNKKCIEDHFDKSIELEFELEKS
GKEELLELVRNISDMVDIHYIRQKEPKGLGHAIHCAKTFVGNEPFAVLLGDDVVDSEKPCLKQLIDCFSEYNTTILGVQT
VAQENVSKYGIVDGLHIEDRVYKVKDLVEKPSVEEAPSNVAILGRYIITPEIFNILENTKPGKGGEIQLTDALKTLISKE
AMYAYNFEGRRYDVGDKLGFLQATVEFALKREELREPFIEYLKGNPWDEK
>Mature_290_residues
MKVKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAVASGIEEILIITGRNKKCIEDHFDKSIELEFELEKS
GKEELLELVRNISDMVDIHYIRQKEPKGLGHAIHCAKTFVGNEPFAVLLGDDVVDSEKPCLKQLIDCFSEYNTTILGVQT
VAQENVSKYGIVDGLHIEDRVYKVKDLVEKPSVEEAPSNVAILGRYIITPEIFNILENTKPGKGGEIQLTDALKTLISKE
AMYAYNFEGRRYDVGDKLGFLQATVEFALKREELREPFIEYLKGNPWDEK

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=291, Percent_Identity=47.0790378006873, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1788355, Length=276, Percent_Identity=43.4782608695652, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1788351, Length=274, Percent_Identity=27.3722627737226, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=29.0598290598291, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355443, Length=275, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644084, Length=275, Percent_Identity=25.4545454545455, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32669; Mature: 32669

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAVASGIEEILIITGRNK
CCCCHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCHHEEEEEECCCC
KCIEDHFDKSIELEFELEKSGKEELLELVRNISDMVDIHYIRQKEPKGLGHAIHCAKTFV
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GNEPFAVLLGDDVVDSEKPCLKQLIDCFSEYNTTILGVQTVAQENVSKYGIVDGLHIEDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCHHHH
VYKVKDLVEKPSVEEAPSNVAILGRYIITPEIFNILENTKPGKGGEIQLTDALKTLISKE
HHHHHHHHHCCCCCCCCCCEEEHHHHHHCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
AMYAYNFEGRRYDVGDKLGFLQATVEFALKREELREPFIEYLKGNPWDEK
HHEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKVKKAIIPAAGLGTRFLPATKAQPKEMLPIVDKPTIQYIIEEAVASGIEEILIITGRNK
CCCCHHHCCCCCCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHCCHHEEEEEECCCC
KCIEDHFDKSIELEFELEKSGKEELLELVRNISDMVDIHYIRQKEPKGLGHAIHCAKTFV
HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GNEPFAVLLGDDVVDSEKPCLKQLIDCFSEYNTTILGVQTVAQENVSKYGIVDGLHIEDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCCCHHHH
VYKVKDLVEKPSVEEAPSNVAILGRYIITPEIFNILENTKPGKGGEIQLTDALKTLISKE
HHHHHHHHHCCCCCCCCCCEEEHHHHHHCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
AMYAYNFEGRRYDVGDKLGFLQATVEFALKREELREPFIEYLKGNPWDEK
HHEEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]