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The map label for this gene is aroB [H]

Identifier: 187933372

GI number: 187933372

Start: 3252937

End: 3253989

Strand: Reverse

Name: aroB [H]

Synonym: CLL_A3143

Alternate gene names: 187933372

Gene position: 3253989-3252937 (Counterclockwise)

Preceding gene: 187935227

Following gene: 187935747

Centisome position: 85.62

GC content: 26.21

Gene sequence:

>1053_bases
ATGAGGGAGTTAGTTGTAGATCTAAAGGAAAAAAGTTATTCAATAATAATTAAAAAGGGATTAATTAATGAACTTAGTAA
TGAAATAAATAAGCTTTATAAAGGGAAAAAGATTTTTATATTAACTGATGAAAATGTAAATTATCACTACGGAGATAAGG
TTAAAGACTTGTTAATTAATAATGGGTATGATGTTAAGAAAATGGTATTAAAACCTGGAGAAGAAACTAAATCTTTTAAT
ACTCTTCCTAAAATATATAATGAATTTTTAGATTTTAAATTAACTAGAAGTGATTTAATTATTACACTTGGAGGAGGAGT
TATAGGAGATCTTGGAGGATTTGCAGCATCTACATTTTTAAGAGGAATTGATTTTATTCAAGTACCTACGTCATTGCTTG
CTCAAGTTGATAGTAGTGTTGGAGGAAAAGTTGCTGTAGATTTAGATAGGGGAAAGAATTTGGTAGGAAGTTTTTATCAT
CCTAAAGTGGTTTTAATTGATCCGGATGTTTTAATTACATTAAAGGATAAATTTTTTAAAGATGGAATGGCTGAAGTTAT
AAAATACGGCTGTATAAAAGATCTGAATTTCTTTTACAAATTGAAAGAGTTTAAATCTAAAGATGAAGTTTTAGATAACA
TAGAAGATATAATTTATACATGTTGTAATATTAAAAGAATAGTTGTGGAGAATGATGAAAAAGATAAAGGTGAGAGAATG
TTACTGAATTTTGGCCATACACTGGGTCATGCAATAGAGTCATACTATAATTTTAATAAATATACGCATGGTGAAGCTGT
AGGAATTGGAATGTATAAAATAATTAAAATGTCTGAAGAAAAGGGAATTACTCCAAAGGGATGTGCAGATGAAATAAAAG
ATATATTAATTCAATATTCACTTCCTTATGATATAGATATTGAAAATTTAGATGAAATACTAGAAACAATTTCTTTAGAT
AAAAAAAATATTAATAATGTTTTAAAGATAGTATTACTTGACAGAATAGGACAATCATTTTTAAAAAGCACTAATATAGA
ATTTTTCAAGTAA

Upstream 100 bases:

>100_bases
AAAATCAAATTCTAATGCCATTTCGCAATTATATTATAATAGCAATCTAATATATTCAAGTATAAATCTTAGATCAAAAC
ATATAAGAAGGAGTATTAAA

Downstream 100 bases:

>100_bases
ATCTTATATTTTGTAACTGTACACTAACAAAAAGCAAATAAGTTTTAATTAATGTATTATCTTAATATTAAACAACTAAA
AGGGGGACACAAATGGGAAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRELVVDLKEKSYSIIIKKGLINELSNEINKLYKGKKIFILTDENVNYHYGDKVKDLLINNGYDVKKMVLKPGEETKSFN
TLPKIYNEFLDFKLTRSDLIITLGGGVIGDLGGFAASTFLRGIDFIQVPTSLLAQVDSSVGGKVAVDLDRGKNLVGSFYH
PKVVLIDPDVLITLKDKFFKDGMAEVIKYGCIKDLNFFYKLKEFKSKDEVLDNIEDIIYTCCNIKRIVVENDEKDKGERM
LLNFGHTLGHAIESYYNFNKYTHGEAVGIGMYKIIKMSEEKGITPKGCADEIKDILIQYSLPYDIDIENLDEILETISLD
KKNINNVLKIVLLDRIGQSFLKSTNIEFFK

Sequences:

>Translated_350_residues
MRELVVDLKEKSYSIIIKKGLINELSNEINKLYKGKKIFILTDENVNYHYGDKVKDLLINNGYDVKKMVLKPGEETKSFN
TLPKIYNEFLDFKLTRSDLIITLGGGVIGDLGGFAASTFLRGIDFIQVPTSLLAQVDSSVGGKVAVDLDRGKNLVGSFYH
PKVVLIDPDVLITLKDKFFKDGMAEVIKYGCIKDLNFFYKLKEFKSKDEVLDNIEDIIYTCCNIKRIVVENDEKDKGERM
LLNFGHTLGHAIESYYNFNKYTHGEAVGIGMYKIIKMSEEKGITPKGCADEIKDILIQYSLPYDIDIENLDEILETISLD
KKNINNVLKIVLLDRIGQSFLKSTNIEFFK
>Mature_350_residues
MRELVVDLKEKSYSIIIKKGLINELSNEINKLYKGKKIFILTDENVNYHYGDKVKDLLINNGYDVKKMVLKPGEETKSFN
TLPKIYNEFLDFKLTRSDLIITLGGGVIGDLGGFAASTFLRGIDFIQVPTSLLAQVDSSVGGKVAVDLDRGKNLVGSFYH
PKVVLIDPDVLITLKDKFFKDGMAEVIKYGCIKDLNFFYKLKEFKSKDEVLDNIEDIIYTCCNIKRIVVENDEKDKGERM
LLNFGHTLGHAIESYYNFNKYTHGEAVGIGMYKIIKMSEEKGITPKGCADEIKDILIQYSLPYDIDIENLDEILETISLD
KKNINNVLKIVLLDRIGQSFLKSTNIEFFK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=346, Percent_Identity=40.1734104046243, Blast_Score=233, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6320332, Length=312, Percent_Identity=38.1410256410256, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39778; Mature: 39778

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELVVDLKEKSYSIIIKKGLINELSNEINKLYKGKKIFILTDENVNYHYGDKVKDLLIN
CCCHHEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHHC
NGYDVKKMVLKPGEETKSFNTLPKIYNEFLDFKLTRSDLIITLGGGVIGDLGGFAASTFL
CCCCHHHHHCCCCCHHHHCCHHHHHHHHHHCCEEECCCEEEEECCCHHHHHHHHHHHHHH
RGIDFIQVPTSLLAQVDSSVGGKVAVDLDRGKNLVGSFYHPKVVLIDPDVLITLKDKFFK
HCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEECHHHHH
DGMAEVIKYGCIKDLNFFYKLKEFKSKDEVLDNIEDIIYTCCNIKRIVVENDEKDKGERM
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHH
LLNFGHTLGHAIESYYNFNKYTHGEAVGIGMYKIIKMSEEKGITPKGCADEIKDILIQYS
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHEEEHHHCCCCCCCHHHHHHHHHHHCC
LPYDIDIENLDEILETISLDKKNINNVLKIVLLDRIGQSFLKSTNIEFFK
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRELVVDLKEKSYSIIIKKGLINELSNEINKLYKGKKIFILTDENVNYHYGDKVKDLLIN
CCCHHEECCCCCEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCEECCCHHHHHHHC
NGYDVKKMVLKPGEETKSFNTLPKIYNEFLDFKLTRSDLIITLGGGVIGDLGGFAASTFL
CCCCHHHHHCCCCCHHHHCCHHHHHHHHHHCCEEECCCEEEEECCCHHHHHHHHHHHHHH
RGIDFIQVPTSLLAQVDSSVGGKVAVDLDRGKNLVGSFYHPKVVLIDPDVLITLKDKFFK
HCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCEEEEECHHHHH
DGMAEVIKYGCIKDLNFFYKLKEFKSKDEVLDNIEDIIYTCCNIKRIVVENDEKDKGERM
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHH
LLNFGHTLGHAIESYYNFNKYTHGEAVGIGMYKIIKMSEEKGITPKGCADEIKDILIQYS
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHEEEHHHCCCCCCCHHHHHHHHHHHCC
LPYDIDIENLDEILETISLDKKNINNVLKIVLLDRIGQSFLKSTNIEFFK
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA