Click here to switch to the map view.

The map label for this gene is pyrR [H]

Identifier: 187935598

GI number: 187935598

Start: 2516637

End: 2517179

Strand: Reverse

Name: pyrR [H]

Synonym: CLL_A2431

Alternate gene names: 187935598

Gene position: 2517179-2516637 (Counterclockwise)

Preceding gene: 187932847

Following gene: 187934404

Centisome position: 66.24

GC content: 29.28

Gene sequence:

>543_bases
ATGGAATTAAAATCAACTTTATTAGATGATAAAGCTATAAAAAGAACATTGATTAGAATTTCTCATGAAATAATTGAAAG
AAATAAAGGAATAGAAGATATAGTCCTTATTGGTATAAAAAGAAGGGGATATCCATTAGCACAGAGAATAGCAGAACATA
TTGAAGGCATTGAAGGTAGTAAAGTAGACGTTGGATATGTTGATATAACTTTGTATAGAGATGACCTTACTATAGTTGAA
AAGGACCCTACAGTTAAGAGCATAGACATAGAAACAACTATAAAGGATAAAAAAGTAATATTAGTTGATGATGTATTATA
TACATGCAGAACAGTTAGAGCTGCTATTGATGCGGTTATGGACTTAGATAGACCTGAAGGTATACAATTAGCAGTTTTGA
TAGATAGAGGACATAAGGAACTACCTATAAGAGCAGATTATGTTGGTAAAAATATACCTACATCTAAAAATGAAGTTATA
AAGGTTATGTTAAATGAAATTGATGGAGAAGATTCTGTAAAGATATATGATTCTATTAATTAG

Upstream 100 bases:

>100_bases
AAAAATGAATACATGGAATTTGAGACTAATTTGCCAGAATACTTTGAAGAAATAATAGAAAAATTAAGATAAAATATAAG
AGGAGATAGGAGGCAAAATT

Downstream 100 bases:

>100_bases
TAGAATATAAGAAAGTTATAAAAGGAGTAATATATGTATAATTTAATTGCAACAAGTACTTTTGGTATAGAAAGTATAAC
AGCTAAAGAACTAAGAGCGC

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MELKSTLLDDKAIKRTLIRISHEIIERNKGIEDIVLIGIKRRGYPLAQRIAEHIEGIEGSKVDVGYVDITLYRDDLTIVE
KDPTVKSIDIETTIKDKKVILVDDVLYTCRTVRAAIDAVMDLDRPEGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVI
KVMLNEIDGEDSVKIYDSIN

Sequences:

>Translated_180_residues
MELKSTLLDDKAIKRTLIRISHEIIERNKGIEDIVLIGIKRRGYPLAQRIAEHIEGIEGSKVDVGYVDITLYRDDLTIVE
KDPTVKSIDIETTIKDKKVILVDDVLYTCRTVRAAIDAVMDLDRPEGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVI
KVMLNEIDGEDSVKIYDSIN
>Mature_180_residues
MELKSTLLDDKAIKRTLIRISHEIIERNKGIEDIVLIGIKRRGYPLAQRIAEHIEGIEGSKVDVGYVDITLYRDDLTIVE
KDPTVKSIDIETTIKDKKVILVDDVLYTCRTVRAAIDAVMDLDRPEGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVI
KVMLNEIDGEDSVKIYDSIN

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20351; Mature: 20351

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKSTLLDDKAIKRTLIRISHEIIERNKGIEDIVLIGIKRRGYPLAQRIAEHIEGIEGS
CCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCC
KVDVGYVDITLYRDDLTIVEKDPTVKSIDIETTIKDKKVILVDDVLYTCRTVRAAIDAVM
EEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHH
DLDRPEGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVIKVMLNEIDGEDSVKIYDSIN
CCCCCCCCEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MELKSTLLDDKAIKRTLIRISHEIIERNKGIEDIVLIGIKRRGYPLAQRIAEHIEGIEGS
CCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCC
KVDVGYVDITLYRDDLTIVEKDPTVKSIDIETTIKDKKVILVDDVLYTCRTVRAAIDAVM
EEEEEEEEEEEEECCEEEEECCCCEEEEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHH
DLDRPEGIQLAVLIDRGHKELPIRADYVGKNIPTSKNEVIKVMLNEIDGEDSVKIYDSIN
CCCCCCCCEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA