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The map label for this gene is 187935440

Identifier: 187935440

GI number: 187935440

Start: 3637023

End: 3638099

Strand: Reverse

Name: 187935440

Synonym: CLL_A3439

Alternate gene names: NA

Gene position: 3638099-3637023 (Counterclockwise)

Preceding gene: 187933145

Following gene: 187933947

Centisome position: 95.73

GC content: 31.57

Gene sequence:

>1077_bases
ATGCATAAAAAATTATTTATTCCAGGACCTGTTGAGGTTCGAGAGGATGTTCTAGAAAAAATGGCAACGCCAATGATAGG
ACATAGAAGTAAGGATGCTTCAATTTTACAAAGAAGAATAAGCGATAATTTAAGAAAGTTATTTTATACAAATAATGAAA
TATTACTTTCTACAACTTCTGGTAGTGGACTTATGGAAGGTGCTATAAGATGTTGTACTGCTAAAAGAGCAGCTGTATTT
TCCGTAGGGGCTTTCGGAAAGAGATGGTATGACATGGCAGTTAATAACAATGTTCCAGCTGATTTATTTTCAGTAGAAAT
GGGACAAGCAATAGATCCAGTTGAAGTAGAAAAAGTATTGAGTACAGGTAAATATGATTTGGTAGCTGTTACTCATAATG
AAACATCAACAGGAGTAATGAATCCAGTTGATAAAATAGGTAATATAGTTAAGAAATATCCTGATGTAGTTTTTATTGTT
GATACAGTAAGTTCAGCAGCAGGGACGAAAATAGAAGTTGATAAATGGGGTATAGATGTTTGTATTACATCATCTCAAAA
GGCCTTAGGTTTGCCTCCAGGATTATCAGTATGTACTTTTTCACAAAAAGCTAAAGAAAGAGCAGAAAAGGTTCAAAATA
GAGGATATTACCTAGATTTATTAAAATTATATCAATATATTCAAAAGAAAGATTATCAATATCCTTCAACACCATCACTT
TCTCACATGTTTGCTCTTGACTACCAATTAGATAATATACTTAATAAAGAAGGACTAGAGAATAGATTTGCAAGACACCT
TGAAATGGCGCAAATTGTTAGAGCATGGGCTAAAAAATATTTTGCAATTTTCCCAGATGAAAATTATCTATCAAATACAT
TAACAACAATTAAAAATACTAGAGGAATAAATGTAGCTGAGCTAAATAAAGAGCTTGGTAAAAGAGGATTCCAAATTTCT
AATGGATATGGTGATTTAAAAGAAAAGACATTTAGAATAGCTCATATGGCAGATTGCACAGTAGAAGATGTAAAGGAATT
GCTTAAAAATATAGAAGAAATTTTAGAGTTGATGTGA

Upstream 100 bases:

>100_bases
GAGTTAAATGTAAATAAGTAGTAAAATATACAAATAAATCAATATTAAATAAGCGTTAGTAAGCAATATAATTTATTAAT
AAAAATGGGGTGGTTTTAAA

Downstream 100 bases:

>100_bases
TGGCTTAAAAAATTGGGGGGATTTTTATGATTAAGGTATTAACAAACGATGGTTTGCAACCTAAAGCTATAGAAAGTTTA
AAAAGTTTGGGTATTGAAGT

Product: serine--glyoxylate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MHKKLFIPGPVEVREDVLEKMATPMIGHRSKDASILQRRISDNLRKLFYTNNEILLSTTSGSGLMEGAIRCCTAKRAAVF
SVGAFGKRWYDMAVNNNVPADLFSVEMGQAIDPVEVEKVLSTGKYDLVAVTHNETSTGVMNPVDKIGNIVKKYPDVVFIV
DTVSSAAGTKIEVDKWGIDVCITSSQKALGLPPGLSVCTFSQKAKERAEKVQNRGYYLDLLKLYQYIQKKDYQYPSTPSL
SHMFALDYQLDNILNKEGLENRFARHLEMAQIVRAWAKKYFAIFPDENYLSNTLTTIKNTRGINVAELNKELGKRGFQIS
NGYGDLKEKTFRIAHMADCTVEDVKELLKNIEEILELM

Sequences:

>Translated_358_residues
MHKKLFIPGPVEVREDVLEKMATPMIGHRSKDASILQRRISDNLRKLFYTNNEILLSTTSGSGLMEGAIRCCTAKRAAVF
SVGAFGKRWYDMAVNNNVPADLFSVEMGQAIDPVEVEKVLSTGKYDLVAVTHNETSTGVMNPVDKIGNIVKKYPDVVFIV
DTVSSAAGTKIEVDKWGIDVCITSSQKALGLPPGLSVCTFSQKAKERAEKVQNRGYYLDLLKLYQYIQKKDYQYPSTPSL
SHMFALDYQLDNILNKEGLENRFARHLEMAQIVRAWAKKYFAIFPDENYLSNTLTTIKNTRGINVAELNKELGKRGFQIS
NGYGDLKEKTFRIAHMADCTVEDVKELLKNIEEILELM
>Mature_358_residues
MHKKLFIPGPVEVREDVLEKMATPMIGHRSKDASILQRRISDNLRKLFYTNNEILLSTTSGSGLMEGAIRCCTAKRAAVF
SVGAFGKRWYDMAVNNNVPADLFSVEMGQAIDPVEVEKVLSTGKYDLVAVTHNETSTGVMNPVDKIGNIVKKYPDVVFIV
DTVSSAAGTKIEVDKWGIDVCITSSQKALGLPPGLSVCTFSQKAKERAEKVQNRGYYLDLLKLYQYIQKKDYQYPSTPSL
SHMFALDYQLDNILNKEGLENRFARHLEMAQIVRAWAKKYFAIFPDENYLSNTLTTIKNTRGINVAELNKELGKRGFQIS
NGYGDLKEKTFRIAHMADCTVEDVKELLKNIEEILELM

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=366, Percent_Identity=28.1420765027322, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17536281, Length=370, Percent_Identity=27.5675675675676, Blast_Score=137, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6321079, Length=382, Percent_Identity=27.4869109947644, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17530823, Length=368, Percent_Identity=27.7173913043478, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 40282; Mature: 40282

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKLFIPGPVEVREDVLEKMATPMIGHRSKDASILQRRISDNLRKLFYTNNEILLSTTS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GSGLMEGAIRCCTAKRAAVFSVGAFGKRWYDMAVNNNVPADLFSVEMGQAIDPVEVEKVL
CCHHHHHHHHHHHHHHHHHEEHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH
STGKYDLVAVTHNETSTGVMNPVDKIGNIVKKYPDVVFIVDTVSSAAGTKIEVDKWGIDV
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCEEE
CITSSQKALGLPPGLSVCTFSQKAKERAEKVQNRGYYLDLLKLYQYIQKKDYQYPSTPSL
EEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
SHMFALDYQLDNILNKEGLENRFARHLEMAQIVRAWAKKYFAIFPDENYLSNTLTTIKNT
HHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCC
RGINVAELNKELGKRGFQISNGYGDLKEKTFRIAHMADCTVEDVKELLKNIEEILELM
CCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHKKLFIPGPVEVREDVLEKMATPMIGHRSKDASILQRRISDNLRKLFYTNNEILLSTTS
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GSGLMEGAIRCCTAKRAAVFSVGAFGKRWYDMAVNNNVPADLFSVEMGQAIDPVEVEKVL
CCHHHHHHHHHHHHHHHHHEEHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH
STGKYDLVAVTHNETSTGVMNPVDKIGNIVKKYPDVVFIVDTVSSAAGTKIEVDKWGIDV
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCEEE
CITSSQKALGLPPGLSVCTFSQKAKERAEKVQNRGYYLDLLKLYQYIQKKDYQYPSTPSL
EEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCC
SHMFALDYQLDNILNKEGLENRFARHLEMAQIVRAWAKKYFAIFPDENYLSNTLTTIKNT
HHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCC
RGINVAELNKELGKRGFQISNGYGDLKEKTFRIAHMADCTVEDVKELLKNIEEILELM
CCCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]