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The map label for this gene is lacA [C]

Identifier: 187935319

GI number: 187935319

Start: 3267256

End: 3267987

Strand: Reverse

Name: lacA [C]

Synonym: CLL_A3151

Alternate gene names: 187935319

Gene position: 3267987-3267256 (Counterclockwise)

Preceding gene: 187933152

Following gene: 187934642

Centisome position: 85.99

GC content: 28.14

Gene sequence:

>732_bases
ATGAAGAAAATAGACGAATTATTATATGAAATAGGAAATATTATTAATCACGGTATAGACAAGGAGGGCGTTATAAAAAT
TTTAGAAATTTTAAATTGTTCTATTCAAGTGGAAATATTAGATGAAATTAAGCTATATGGAGATTATTTACCTAAAATTT
CAGAAAATGGCATGTCGGAGGAAAAAAGATATTTACATTTTTTATGGGATGTATTGGACAAGTCTCCAATGTGCCTTATA
GCAAACTTTGCAATCCCATACAGAAGAATTTTAGCTAAAAAATTATTTAAGTCTTGTGGAAAAAATTTCATAGCAGAAGA
AAATGTTAGATTTAATATACCAGATAACATTGAGTTTGGTGATGATGTATTCATTAATAGAGGAACTTTTATAGATTCTA
AGGGTGGAATTAAAATTGGAAGTTTTGTTGGGATAGGAGAGGGGGTAACTATAATCACTCATTCTCATAAAGAAGATAAT
CATTCATCAAGAGATTATGGCGAAGTAATAATAGAAGATTATGCCAAAATATATTCTAATTCCACAATACTTTTAGGCGT
AAAAATTAAAAAGAAGGCCATAGTTGCGGCTTGTTCTTTAGTAAATAAGGATATTAAAGAGAATACAATAGTTGCAGGTA
TACCAGCAAAAGAATTTAGAGAAAGAAATACCTTTGGTAAAAGTGAATTAAATCATGTATGGCTTCATAATAAAAGTTTT
CAAAATAAATAA

Upstream 100 bases:

>100_bases
ATAGTAATTTATAGAGTTGATTTATATTACTTAAAGAAGAAAAAATTAATTTAAGAGAGGAGAAAATAATTATTAATTTA
TTTAATAATTATTAATAATC

Downstream 100 bases:

>100_bases
AGATTTTTAAGTAGAACTATAAATTTTTAAATATTATTATAGGTTACAATTTTAAAAATTATTAAATATGTAAAATTATA
AAAAATATTATTAGGAGGGT

Product: maltose transacetylase

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: Transferase Hexapeptide Repeat Containing Protein; Maltose Transacetylase; Hexapaptide Repeat-Containing Transferase; Acetyltransferase-Like; Acetyltransferase-Like Protein

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKKIDELLYEIGNIINHGIDKEGVIKILEILNCSIQVEILDEIKLYGDYLPKISENGMSEEKRYLHFLWDVLDKSPMCLI
ANFAIPYRRILAKKLFKSCGKNFIAEENVRFNIPDNIEFGDDVFINRGTFIDSKGGIKIGSFVGIGEGVTIITHSHKEDN
HSSRDYGEVIIEDYAKIYSNSTILLGVKIKKKAIVAACSLVNKDIKENTIVAGIPAKEFRERNTFGKSELNHVWLHNKSF
QNK

Sequences:

>Translated_243_residues
MKKIDELLYEIGNIINHGIDKEGVIKILEILNCSIQVEILDEIKLYGDYLPKISENGMSEEKRYLHFLWDVLDKSPMCLI
ANFAIPYRRILAKKLFKSCGKNFIAEENVRFNIPDNIEFGDDVFINRGTFIDSKGGIKIGSFVGIGEGVTIITHSHKEDN
HSSRDYGEVIIEDYAKIYSNSTILLGVKIKKKAIVAACSLVNKDIKENTIVAGIPAKEFRERNTFGKSELNHVWLHNKSF
QNK
>Mature_243_residues
MKKIDELLYEIGNIINHGIDKEGVIKILEILNCSIQVEILDEIKLYGDYLPKISENGMSEEKRYLHFLWDVLDKSPMCLI
ANFAIPYRRILAKKLFKSCGKNFIAEENVRFNIPDNIEFGDDVFINRGTFIDSKGGIKIGSFVGIGEGVTIITHSHKEDN
HSSRDYGEVIIEDYAKIYSNSTILLGVKIKKKAIVAACSLVNKDIKENTIVAGIPAKEFRERNTFGKSELNHVWLHNKSF
QNK

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786537, Length=141, Percent_Identity=31.9148936170213, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 27623; Mature: 27623

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIDELLYEIGNIINHGIDKEGVIKILEILNCSIQVEILDEIKLYGDYLPKISENGMSE
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCH
EKRYLHFLWDVLDKSPMCLIANFAIPYRRILAKKLFKSCGKNFIAEENVRFNIPDNIEFG
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCC
DDVFINRGTFIDSKGGIKIGSFVGIGEGVTIITHSHKEDNHSSRDYGEVIIEDYAKIYSN
CCEEEECCCEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
STILLGVKIKKKAIVAACSLVNKDIKENTIVAGIPAKEFRERNTFGKSELNHVWLHNKSF
CEEEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCCCCEEEEECCCC
QNK
CCC
>Mature Secondary Structure
MKKIDELLYEIGNIINHGIDKEGVIKILEILNCSIQVEILDEIKLYGDYLPKISENGMSE
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCH
EKRYLHFLWDVLDKSPMCLIANFAIPYRRILAKKLFKSCGKNFIAEENVRFNIPDNIEFG
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCC
DDVFINRGTFIDSKGGIKIGSFVGIGEGVTIITHSHKEDNHSSRDYGEVIIEDYAKIYSN
CCEEEECCCEEECCCCEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
STILLGVKIKKKAIVAACSLVNKDIKENTIVAGIPAKEFRERNTFGKSELNHVWLHNKSF
CEEEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCCCCEEEEECCCC
QNK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA