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The map label for this gene is yugT [H]

Identifier: 187935251

GI number: 187935251

Start: 3741285

End: 3742952

Strand: Reverse

Name: yugT [H]

Synonym: CLL_A3534

Alternate gene names: 187935251

Gene position: 3742952-3741285 (Counterclockwise)

Preceding gene: 187934421

Following gene: 187932863

Centisome position: 98.49

GC content: 27.16

Gene sequence:

>1668_bases
ATGATAAAAAAATGGTGGCATGATAAAGTAGCATATCAAATATATCCTAAAAGTTTTAATGATTCTAATGGAGATGGAAT
AGGTGATTTAAGAGGAATTATTAATAAACTTGATTATTTAAAAGAATTAGGAGTAGATATAATTTGGATTTCTCCAGTTT
ATTGCTCTCCAATGGTAGACCAAGGTTATGATATTTCTGATTATTATAATATAGATCCTAGATTTGGAACAATGGAAGAT
ATGGATGAGTTATTAAAAGAAGCTAAATCAAGAGATATGCATATATTAATGGATTTAGTTGTTAATCATTGTTCTGATCA
ACATGAATGGTTTAAGAAAGCTATAGCAGATCCAGATGGTGAATATGCGGATTATTTTTATTTTAGAGAAGGTAAAAATG
GAAATCCACCATGTAACTGGCGTTCATATTTTGGAGGCAGTGTATGGGAGAAGATACCTAACAGTAATAAATATTATCTA
CATTTATTTGCTAAGGAACAACCAGATTTAAATTGGGAAAACCCTAAATTGAGAAAAAAAATATATGAAATGATTAACTG
GTGGCTTGAAAAAGGATTATCAGGATTTAGAATTGATGCGATTATTAATATAAAAAAGGATTTAAGATTTGAAGATTTTC
CATCTGATAGAGAGGATGGTCTTTGCAGTTTATATAATATGTTGAATGCAGCAAAAGGCGTTGGGGATATGCTTAATGAA
TTAAAAAGAGAAACTTTTGATAAGTTTGATGCATTTACTGTAGGTGAGGTATTTAATGAAAAAGAAGATGAGCTTTATAA
ATTTATAGGAAAAGATGGATATTTTTCTTCTATGTTTGATTTTAGTATGAGCATGTTAGGTGGTAATGAAAAAGGCTGGT
ATGGTTATTGTGATTTTAAGACAAATGAATTAAGAAAGGTAATTTTTGATAGTCAGGTAAAAACTGCTGATATAGGATTT
AAAGCAAATATTATTGAAAACCATGATGAACCAAGAGGGGTAAGCAGATATATACCTGCTGAAGATTGTAATGATTATAG
TAAAAAGATGCTGGCAGCTATATCACTTATGTTAAAGGGAATTCCGTTTATATATCAAGGACAAGAAATTGGAATGACAA
ATAATAAATTTAATTCTATAAAAGAGATAGATGATATTTCAACAATAGATCAATATAAGGTTGCTATAGAACATGGATTT
AATGAGATAGAATCATTAAAAATTGTAAATAAATATAGTAGAGACAATGCTAGAACTCCATTCCATTGGAATAACGGTAA
AAATGCAGGATTTACAGAAGGAAAGCCATGGATTACTATAAATGAAAATTATAAACATATAAATGCAGAATCACAAATTA
GTGATGAAAATTCAGTAATTAGTTTTTATAAGAAGCTTATAAAATTAAGAAAATCTGATGAATTTAAGGATGCTATAGTT
TATGGAGAATTTAAACCTACTTTAGAACAATATGATAATATATTCTCTTTTTACAGAAAAGGTAAAGAGAAAAAATTAAT
GTTAATAGCTAATTATCAAAAAGACGAATATAAAATAAGAATACCAAGTCTTCCTAAAAAAGTTTTAATTAATAACTATG
AAACAATAACTATTGAAGAAAATGAATTAAATTTACAAGGATATCAAGTATTAATTTTAGAAATTTAA

Upstream 100 bases:

>100_bases
GTATTATATAACTATAGTAAAACAACGAGAGTCTTATGAGGAGGTGAATTTTAGTAAGAGATTAATAGTAAATATTTAAA
TATCTTACTAAATATAAATT

Downstream 100 bases:

>100_bases
TAGCAATATAAATAATAGTAAAACTAAGTTTTTAATTATTTAGGTACATGAAAATAAATAATAAGTTCAAAATTGCAATG
GAAAACAGGCTGGCAAATGG

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Oligosaccharide alpha-1,6-glucosidase 3; Sucrase-isomaltase 3; Isomaltase 3 [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MIKKWWHDKVAYQIYPKSFNDSNGDGIGDLRGIINKLDYLKELGVDIIWISPVYCSPMVDQGYDISDYYNIDPRFGTMED
MDELLKEAKSRDMHILMDLVVNHCSDQHEWFKKAIADPDGEYADYFYFREGKNGNPPCNWRSYFGGSVWEKIPNSNKYYL
HLFAKEQPDLNWENPKLRKKIYEMINWWLEKGLSGFRIDAIINIKKDLRFEDFPSDREDGLCSLYNMLNAAKGVGDMLNE
LKRETFDKFDAFTVGEVFNEKEDELYKFIGKDGYFSSMFDFSMSMLGGNEKGWYGYCDFKTNELRKVIFDSQVKTADIGF
KANIIENHDEPRGVSRYIPAEDCNDYSKKMLAAISLMLKGIPFIYQGQEIGMTNNKFNSIKEIDDISTIDQYKVAIEHGF
NEIESLKIVNKYSRDNARTPFHWNNGKNAGFTEGKPWITINENYKHINAESQISDENSVISFYKKLIKLRKSDEFKDAIV
YGEFKPTLEQYDNIFSFYRKGKEKKLMLIANYQKDEYKIRIPSLPKKVLINNYETITIEENELNLQGYQVLILEI

Sequences:

>Translated_555_residues
MIKKWWHDKVAYQIYPKSFNDSNGDGIGDLRGIINKLDYLKELGVDIIWISPVYCSPMVDQGYDISDYYNIDPRFGTMED
MDELLKEAKSRDMHILMDLVVNHCSDQHEWFKKAIADPDGEYADYFYFREGKNGNPPCNWRSYFGGSVWEKIPNSNKYYL
HLFAKEQPDLNWENPKLRKKIYEMINWWLEKGLSGFRIDAIINIKKDLRFEDFPSDREDGLCSLYNMLNAAKGVGDMLNE
LKRETFDKFDAFTVGEVFNEKEDELYKFIGKDGYFSSMFDFSMSMLGGNEKGWYGYCDFKTNELRKVIFDSQVKTADIGF
KANIIENHDEPRGVSRYIPAEDCNDYSKKMLAAISLMLKGIPFIYQGQEIGMTNNKFNSIKEIDDISTIDQYKVAIEHGF
NEIESLKIVNKYSRDNARTPFHWNNGKNAGFTEGKPWITINENYKHINAESQISDENSVISFYKKLIKLRKSDEFKDAIV
YGEFKPTLEQYDNIFSFYRKGKEKKLMLIANYQKDEYKIRIPSLPKKVLINNYETITIEENELNLQGYQVLILEI
>Mature_555_residues
MIKKWWHDKVAYQIYPKSFNDSNGDGIGDLRGIINKLDYLKELGVDIIWISPVYCSPMVDQGYDISDYYNIDPRFGTMED
MDELLKEAKSRDMHILMDLVVNHCSDQHEWFKKAIADPDGEYADYFYFREGKNGNPPCNWRSYFGGSVWEKIPNSNKYYL
HLFAKEQPDLNWENPKLRKKIYEMINWWLEKGLSGFRIDAIINIKKDLRFEDFPSDREDGLCSLYNMLNAAKGVGDMLNE
LKRETFDKFDAFTVGEVFNEKEDELYKFIGKDGYFSSMFDFSMSMLGGNEKGWYGYCDFKTNELRKVIFDSQVKTADIGF
KANIIENHDEPRGVSRYIPAEDCNDYSKKMLAAISLMLKGIPFIYQGQEIGMTNNKFNSIKEIDDISTIDQYKVAIEHGF
NEIESLKIVNKYSRDNARTPFHWNNGKNAGFTEGKPWITINENYKHINAESQISDENSVISFYKKLIKLRKSDEFKDAIV
YGEFKPTLEQYDNIFSFYRKGKEKKLMLIANYQKDEYKIRIPSLPKKVLINNYETITIEENELNLQGYQVLILEI

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=561, Percent_Identity=28.3422459893048, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI65506891, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744477, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744483, Length=134, Percent_Identity=30.5970149253731, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744475, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744479, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI61744481, Length=136, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790687, Length=555, Percent_Identity=37.6576576576577, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1786604, Length=361, Percent_Identity=23.2686980609418, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32565753, Length=500, Percent_Identity=25.8, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=569, Percent_Identity=23.1985940246046, Blast_Score=108, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322245, Length=546, Percent_Identity=37.9120879120879, Blast_Score=339, Evalue=8e-94,
Organism=Saccharomyces cerevisiae, GI6321726, Length=579, Percent_Identity=34.3696027633851, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6319776, Length=544, Percent_Identity=36.0294117647059, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6322241, Length=586, Percent_Identity=35.4948805460751, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6322021, Length=586, Percent_Identity=35.4948805460751, Blast_Score=306, Evalue=5e-84,
Organism=Saccharomyces cerevisiae, GI6321731, Length=544, Percent_Identity=35.8455882352941, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6324416, Length=586, Percent_Identity=35.4948805460751, Blast_Score=305, Evalue=2e-83,
Organism=Drosophila melanogaster, GI221330053, Length=594, Percent_Identity=33.8383838383838, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24583749, Length=487, Percent_Identity=37.3716632443532, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24583747, Length=487, Percent_Identity=37.3716632443532, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24586599, Length=495, Percent_Identity=36.1616161616162, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24583745, Length=532, Percent_Identity=35.3383458646617, Blast_Score=278, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24586597, Length=496, Percent_Identity=34.4758064516129, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24586593, Length=495, Percent_Identity=34.7474747474747, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24586589, Length=554, Percent_Identity=33.9350180505415, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24586587, Length=545, Percent_Identity=32.1100917431193, Blast_Score=251, Evalue=9e-67,
Organism=Drosophila melanogaster, GI45549022, Length=510, Percent_Identity=32.5490196078431, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24586591, Length=202, Percent_Identity=48.5148514851485, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI281360393, Length=441, Percent_Identity=31.5192743764172, Blast_Score=193, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 65020; Mature: 65020

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKWWHDKVAYQIYPKSFNDSNGDGIGDLRGIINKLDYLKELGVDIIWISPVYCSPMVD
CCCCHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCC
QGYDISDYYNIDPRFGTMEDMDELLKEAKSRDMHILMDLVVNHCSDQHEWFKKAIADPDG
CCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EYADYFYFREGKNGNPPCNWRSYFGGSVWEKIPNSNKYYLHLFAKEQPDLNWENPKLRKK
CCEEEEEEECCCCCCCCCCCHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHH
IYEMINWWLEKGLSGFRIDAIINIKKDLRFEDFPSDREDGLCSLYNMLNAAKGVGDMLNE
HHHHHHHHHHCCCCCEEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKRETFDKFDAFTVGEVFNEKEDELYKFIGKDGYFSSMFDFSMSMLGGNEKGWYGYCDFK
HHHHHHHHHCCEEHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
TNELRKVIFDSQVKTADIGFKANIIENHDEPRGVSRYIPAEDCNDYSKKMLAAISLMLKG
HHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
IPFIYQGQEIGMTNNKFNSIKEIDDISTIDQYKVAIEHGFNEIESLKIVNKYSRDNARTP
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
FHWNNGKNAGFTEGKPWITINENYKHINAESQISDENSVISFYKKLIKLRKSDEFKDAIV
EEECCCCCCCCCCCCCEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
YGEFKPTLEQYDNIFSFYRKGKEKKLMLIANYQKDEYKIRIPSLPKKVLINNYETITIEE
ECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHCCCEEEEEEC
NELNLQGYQVLILEI
CCCCCCCEEEEEEEC
>Mature Secondary Structure
MIKKWWHDKVAYQIYPKSFNDSNGDGIGDLRGIINKLDYLKELGVDIIWISPVYCSPMVD
CCCCHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCEECCCCCC
QGYDISDYYNIDPRFGTMEDMDELLKEAKSRDMHILMDLVVNHCSDQHEWFKKAIADPDG
CCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EYADYFYFREGKNGNPPCNWRSYFGGSVWEKIPNSNKYYLHLFAKEQPDLNWENPKLRKK
CCEEEEEEECCCCCCCCCCCHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHH
IYEMINWWLEKGLSGFRIDAIINIKKDLRFEDFPSDREDGLCSLYNMLNAAKGVGDMLNE
HHHHHHHHHHCCCCCEEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LKRETFDKFDAFTVGEVFNEKEDELYKFIGKDGYFSSMFDFSMSMLGGNEKGWYGYCDFK
HHHHHHHHHCCEEHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
TNELRKVIFDSQVKTADIGFKANIIENHDEPRGVSRYIPAEDCNDYSKKMLAAISLMLKG
HHHHHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
IPFIYQGQEIGMTNNKFNSIKEIDDISTIDQYKVAIEHGFNEIESLKIVNKYSRDNARTP
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
FHWNNGKNAGFTEGKPWITINENYKHINAESQISDENSVISFYKKLIKLRKSDEFKDAIV
EEECCCCCCCCCCCCCEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEE
YGEFKPTLEQYDNIFSFYRKGKEKKLMLIANYQKDEYKIRIPSLPKKVLINNYETITIEE
ECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHCCCEEEEEEC
NELNLQGYQVLILEI
CCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]