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The map label for this gene is yugH [H]

Identifier: 187935229

GI number: 187935229

Start: 3062222

End: 3063391

Strand: Reverse

Name: yugH [H]

Synonym: CLL_A2976

Alternate gene names: 187935229

Gene position: 3063391-3062222 (Counterclockwise)

Preceding gene: 187934096

Following gene: 187933813

Centisome position: 80.61

GC content: 31.71

Gene sequence:

>1170_bases
ATGATACTAGAGAATATGATTAAGAATAACGTAAGAGAAATGCCACCATCAGGAATAAGAAAATATTTTGATATGATTAA
TGAAATGGAAGGGGTTATATCTTTAGGTGTTGGTGAACCTGATTTCGTTACTCCTTGGAGTGTTAGAGAAGCAGGAATTT
ATTCATTAGAAAAAGGACACACTCATTATTCATCAAATGCAGGATTTATAGAACTTAGACATGAAATATCTAAGTATTTA
TATAGAAGATTTAATCTTAGTTATAATCCGACTGATGAAATAATAGTAACAGTAGGTGGAAGTGAAGGAATAGATATAGC
ACTTAGAGCATTAGTTGGACCTGGAGATGAAGTTATAATACCAGAACCAAGTTTTGTTGCATACAAGGGGTGTACAGCTT
TTACAGGAGCAACACCTAAAGTTATAAATCTTAGAGCAGAAGATGAATTTAAACTTACTCCAGAACTTTTAGAGGAAGCA
ATAACTCCAAAAACTAAAGTTGTAATAATACCGTTTCCTAATAATCCAACTGGTGCAATTATGACTAGAGAAGAATTGAC
TAAAATAGTAGAAGTTTTAAAAGACAAAGATATAATTGTTATATCTGATGAGATATATGCAGAGCTTTGTTATGATGAGG
AACACGTTTCTATAGCATCTTTCCCAGAAATGAGAGATAAAACATTAGTTATAAATGGTTTTTCAAAAGCCTATGCTATG
ACAGGATGGAGACTAGGATATTTATGTGGACATCCAACTTTAATAGACGCTATGAAAAAAATACATCAGTATGCTATAAT
GTGTTCGCCAACAACAGCTCAATATGCAGCAATAGAGGCAATGAAAAATGGTGATAAAAATGTACAGACAATGGTTAGAG
AGTACAATAGAAGAAGAAGAGTATTAGTTGATGGATTTAGAAAAATGGGCTTAGATTGTTTTGAACCATTAGGAGCATTT
TATGTATTTCCATCTATAAAGTCAACAGGTATGACATCTGATGAATTTTGTGAACAACTTCTTATAAATGAAAAAGTACT
TACTGTTCCAGGAAATGCATTTGGTGATTGTGGCGAAGGTTTTATTAGAGCTTGTTATGCATCTTCTATGGATAATATAA
TGGAAGCACTTAAAAGAATAGAAAGATTTATTGATAAAATAAACAAGTAA

Upstream 100 bases:

>100_bases
ATGTATTAAGTACTAGTACACATTTTGTTTTAAGAAAATATAAGGATCATGGAACAATATTTAAAGAAAAGAAAATTGAT
GATAGGGAGGCAATATTTAT

Downstream 100 bases:

>100_bases
ATAAACAAGTACTACTAAAAATTGAAGCTATTTTAAGTATTTAAATAGCTTCAATTTTTTATTAAATATAAATAAACGAA
TATTAAATAAATTATAAGTT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MILENMIKNNVREMPPSGIRKYFDMINEMEGVISLGVGEPDFVTPWSVREAGIYSLEKGHTHYSSNAGFIELRHEISKYL
YRRFNLSYNPTDEIIVTVGGSEGIDIALRALVGPGDEVIIPEPSFVAYKGCTAFTGATPKVINLRAEDEFKLTPELLEEA
ITPKTKVVIIPFPNNPTGAIMTREELTKIVEVLKDKDIIVISDEIYAELCYDEEHVSIASFPEMRDKTLVINGFSKAYAM
TGWRLGYLCGHPTLIDAMKKIHQYAIMCSPTTAQYAAIEAMKNGDKNVQTMVREYNRRRRVLVDGFRKMGLDCFEPLGAF
YVFPSIKSTGMTSDEFCEQLLINEKVLTVPGNAFGDCGEGFIRACYASSMDNIMEALKRIERFIDKINK

Sequences:

>Translated_389_residues
MILENMIKNNVREMPPSGIRKYFDMINEMEGVISLGVGEPDFVTPWSVREAGIYSLEKGHTHYSSNAGFIELRHEISKYL
YRRFNLSYNPTDEIIVTVGGSEGIDIALRALVGPGDEVIIPEPSFVAYKGCTAFTGATPKVINLRAEDEFKLTPELLEEA
ITPKTKVVIIPFPNNPTGAIMTREELTKIVEVLKDKDIIVISDEIYAELCYDEEHVSIASFPEMRDKTLVINGFSKAYAM
TGWRLGYLCGHPTLIDAMKKIHQYAIMCSPTTAQYAAIEAMKNGDKNVQTMVREYNRRRRVLVDGFRKMGLDCFEPLGAF
YVFPSIKSTGMTSDEFCEQLLINEKVLTVPGNAFGDCGEGFIRACYASSMDNIMEALKRIERFIDKINK
>Mature_389_residues
MILENMIKNNVREMPPSGIRKYFDMINEMEGVISLGVGEPDFVTPWSVREAGIYSLEKGHTHYSSNAGFIELRHEISKYL
YRRFNLSYNPTDEIIVTVGGSEGIDIALRALVGPGDEVIIPEPSFVAYKGCTAFTGATPKVINLRAEDEFKLTPELLEEA
ITPKTKVVIIPFPNNPTGAIMTREELTKIVEVLKDKDIIVISDEIYAELCYDEEHVSIASFPEMRDKTLVINGFSKAYAM
TGWRLGYLCGHPTLIDAMKKIHQYAIMCSPTTAQYAAIEAMKNGDKNVQTMVREYNRRRRVLVDGFRKMGLDCFEPLGAF
YVFPSIKSTGMTSDEFCEQLLINEKVLTVPGNAFGDCGEGFIRACYASSMDNIMEALKRIERFIDKINK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=315, Percent_Identity=28.2539682539683, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI169881279, Length=315, Percent_Identity=28.2539682539683, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI56713256, Length=388, Percent_Identity=28.8659793814433, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI56713254, Length=388, Percent_Identity=28.8659793814433, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI169881281, Length=231, Percent_Identity=28.1385281385281, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=25.4593175853018, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=24.4565217391304, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI19263340, Length=368, Percent_Identity=24.4565217391304, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI187936925, Length=407, Percent_Identity=22.6044226044226, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI14211921, Length=407, Percent_Identity=22.6044226044226, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI149944424, Length=250, Percent_Identity=30, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788722, Length=357, Percent_Identity=32.7731092436975, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=26.3157894736842, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788627, Length=378, Percent_Identity=28.8359788359788, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1787710, Length=240, Percent_Identity=24.5833333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790797, Length=331, Percent_Identity=24.1691842900302, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788332, Length=171, Percent_Identity=25.7309941520468, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=388, Percent_Identity=28.0927835051546, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71994472, Length=263, Percent_Identity=33.0798479087452, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=263, Percent_Identity=33.0798479087452, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=25.2032520325203, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=344, Percent_Identity=24.1279069767442, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=257, Percent_Identity=31.5175097276265, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=372, Percent_Identity=24.7311827956989, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=338, Percent_Identity=23.9644970414201, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=25.3886010362694, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=25.3886010362694, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=25.3886010362694, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=25.3886010362694, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=23.0569948186528, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641770, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641760, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641768, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641766, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641764, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45551451, Length=393, Percent_Identity=26.7175572519084, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356535, Length=371, Percent_Identity=25.6064690026954, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43760; Mature: 43760

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILENMIKNNVREMPPSGIRKYFDMINEMEGVISLGVGEPDFVTPWSVREAGIYSLEKGH
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHCCCEEECCCC
THYSSNAGFIELRHEISKYLYRRFNLSYNPTDEIIVTVGGSEGIDIALRALVGPGDEVII
CEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHEEHHHCCCCCEEEE
PEPSFVAYKGCTAFTGATPKVINLRAEDEFKLTPELLEEAITPKTKVVIIPFPNNPTGAI
CCCCEEEECCCCEECCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCE
MTREELTKIVEVLKDKDIIVISDEIYAELCYDEEHVSIASFPEMRDKTLVINGFSKAYAM
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCHHHHHH
TGWRLGYLCGHPTLIDAMKKIHQYAIMCSPTTAQYAAIEAMKNGDKNVQTMVREYNRRRR
CCCEEEECCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VLVDGFRKMGLDCFEPLGAFYVFPSIKSTGMTSDEFCEQLLINEKVLTVPGNAFGDCGEG
HHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCHHHH
FIRACYASSMDNIMEALKRIERFIDKINK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILENMIKNNVREMPPSGIRKYFDMINEMEGVISLGVGEPDFVTPWSVREAGIYSLEKGH
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCHHCCCEEECCCC
THYSSNAGFIELRHEISKYLYRRFNLSYNPTDEIIVTVGGSEGIDIALRALVGPGDEVII
CEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHEEHHHCCCCCEEEE
PEPSFVAYKGCTAFTGATPKVINLRAEDEFKLTPELLEEAITPKTKVVIIPFPNNPTGAI
CCCCEEEECCCCEECCCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCE
MTREELTKIVEVLKDKDIIVISDEIYAELCYDEEHVSIASFPEMRDKTLVINGFSKAYAM
EEHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCEECCCCCCCCCEEEEECCHHHHHH
TGWRLGYLCGHPTLIDAMKKIHQYAIMCSPTTAQYAAIEAMKNGDKNVQTMVREYNRRRR
CCCEEEECCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VLVDGFRKMGLDCFEPLGAFYVFPSIKSTGMTSDEFCEQLLINEKVLTVPGNAFGDCGEG
HHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCHHHH
FIRACYASSMDNIMEALKRIERFIDKINK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]