Click here to switch to the map view.

The map label for this gene is deoD [H]

Identifier: 187935222

GI number: 187935222

Start: 3054092

End: 3054802

Strand: Reverse

Name: deoD [H]

Synonym: CLL_A2969

Alternate gene names: 187935222

Gene position: 3054802-3054092 (Counterclockwise)

Preceding gene: 187934737

Following gene: 187934621

Centisome position: 80.38

GC content: 32.77

Gene sequence:

>711_bases
ATGAGTATTCATATTAATGCACCAGAAGGTGCAATTGCAGAAAGCATATTATTACCAGGAGATCCTTTAAGAGCTAAGTT
TATAGCTGAAAATTTTTTAGAAGATGTAGTTTGCTATAATGAAGTTAGAGGCATGTACGGATTTACAGGAACTTATAAGG
GGAAAAGAGTTTCAGTTCAAGGAACAGGTATGGGAGTACCATCAATATCAATCTATGTTAATGAATTAATTCAAAGTTAT
GGAGTAAAAAATCTTATAAGAGTTGGAACATGTGGTGGATATCATGAAAAGGTTAAGGTTAGAGATCTTGTAATTGCAAT
GTCAGCATGTACTGATTCAAATCTTAATTTAGTAAGATTCCAAGGAAGAACATATGCACCAACTGCAAGCTTTGACTTAT
TAAAACCAGCTTATGATTTAGCAGTAGAAAAAGGTTTTGAACCTAAGGTTGGACCTATATATAGTTCTGATATATTTTAT
GGCGATGATAATGAAGATTGGAAAAAATGGGCTGATTTTGGCTGCCTAGGAGTTGAAATGGAAGCTGCTGCATTATATAC
CATTGCAGCTAAATATAATGTTAATGCATTAGCATTACTTACAGTAAGTGATCATTTTATAACAGGTGAAGTAACTAGTG
CAGAAGAAAGACAAACAACATTTACAAATATGATTGAAGTTGCGTTAGATACTATAGTAGGCATGAAATAA

Upstream 100 bases:

>100_bases
GAAATTTTACCAGGTACATTTACAAAAGTAGATTTAGATAAAAATAATAAATAAAGATGTATTTTAGTATATAAAAATTA
GATTGTATGGAGGTAACAAA

Downstream 100 bases:

>100_bases
TAATTTAATTATAAATAAAATGTATTTGAAATACATTTTTAAATGAACTTATAAAAAGAAGCATTGGAATTCCAAAAGCT
TCTTTTTACCTTATAGATAA

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSIHINAPEGAIAESILLPGDPLRAKFIAENFLEDVVCYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSY
GVKNLIRVGTCGGYHEKVKVRDLVIAMSACTDSNLNLVRFQGRTYAPTASFDLLKPAYDLAVEKGFEPKVGPIYSSDIFY
GDDNEDWKKWADFGCLGVEMEAAALYTIAAKYNVNALALLTVSDHFITGEVTSAEERQTTFTNMIEVALDTIVGMK

Sequences:

>Translated_236_residues
MSIHINAPEGAIAESILLPGDPLRAKFIAENFLEDVVCYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSY
GVKNLIRVGTCGGYHEKVKVRDLVIAMSACTDSNLNLVRFQGRTYAPTASFDLLKPAYDLAVEKGFEPKVGPIYSSDIFY
GDDNEDWKKWADFGCLGVEMEAAALYTIAAKYNVNALALLTVSDHFITGEVTSAEERQTTFTNMIEVALDTIVGMK
>Mature_235_residues
SIHINAPEGAIAESILLPGDPLRAKFIAENFLEDVVCYNEVRGMYGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYG
VKNLIRVGTCGGYHEKVKVRDLVIAMSACTDSNLNLVRFQGRTYAPTASFDLLKPAYDLAVEKGFEPKVGPIYSSDIFYG
DDNEDWKKWADFGCLGVEMEAAALYTIAAKYNVNALALLTVSDHFITGEVTSAEERQTTFTNMIEVALDTIVGMK

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=53.0434782608696, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1790265, Length=228, Percent_Identity=26.7543859649123, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25854; Mature: 25723

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHINAPEGAIAESILLPGDPLRAKFIAENFLEDVVCYNEVRGMYGFTGTYKGKRVSVQ
CEEEEECCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYGVKNLIRVGTCGGYHEKVKVRDLVIAMSACTDSNLNLVRF
ECCCCCCHHHHHHHHHHHHHCHHHEEEECCCCCCHHHEEHHHEEEEEECCCCCCCEEEEE
QGRTYAPTASFDLLKPAYDLAVEKGFEPKVGPIYSSDIFYGDDNEDWKKWADFGCLGVEM
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEECCCCHHHHHHHCCCEEEEEE
EAAALYTIAAKYNVNALALLTVSDHFITGEVTSAEERQTTFTNMIEVALDTIVGMK
HHEEEEEEEEECCCCEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIHINAPEGAIAESILLPGDPLRAKFIAENFLEDVVCYNEVRGMYGFTGTYKGKRVSVQ
EEEEECCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIQSYGVKNLIRVGTCGGYHEKVKVRDLVIAMSACTDSNLNLVRF
ECCCCCCHHHHHHHHHHHHHCHHHEEEECCCCCCHHHEEHHHEEEEEECCCCCCCEEEEE
QGRTYAPTASFDLLKPAYDLAVEKGFEPKVGPIYSSDIFYGDDNEDWKKWADFGCLGVEM
CCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEECCCCHHHHHHHCCCEEEEEE
EAAALYTIAAKYNVNALALLTVSDHFITGEVTSAEERQTTFTNMIEVALDTIVGMK
HHEEEEEEEEECCCCEEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA