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The map label for this gene is scrA [H]

Identifier: 187934943

GI number: 187934943

Start: 3654731

End: 3656086

Strand: Reverse

Name: scrA [H]

Synonym: CLL_A3458

Alternate gene names: 187934943

Gene position: 3656086-3654731 (Counterclockwise)

Preceding gene: 187932935

Following gene: 187934038

Centisome position: 96.2

GC content: 32.96

Gene sequence:

>1356_bases
ATGAAAGAGCAAGTTGTGGCGCAAGAGATATTAAAAAGTATCGGGGGAAAAGAAAATATAAAGTCTATAGAGCATTGTGC
AACCAGACTTAGAATTATACTAAAAGATAAAGAAAAAATTAATGAAAAATCAATAGAAAATATAGATGGAGTTAAAGGTC
AGTTTTTTGCAGCAGGTCAATATCAAGTTATTTTAGGAACAGGATTCGTTAATAAGGTATATGCACAAATAGTTAATGAA
TCAGATAATTTAGCCAATACTAGCGCAAAAGAAGATGCATATAGTGAAATGACAATGTTACAAAAGATTTCTAGAACTTT
TGGTGATGTATTTGTTCCAATAATTCCTGTATTAGTAGCAACAGGATTATTCATGGGATTAAGAGGCTTACTTCAAAATT
TAGGTGTTGAAATGAATGAAAACTTTCTTCTTTTCACACAAGTTTTAACAGATACAGCATTTGCATTCTTACCAGCATTA
GTTGCATGGTCAACAATGAAAAAATTTGGTGGAACACCAGTTATAGGTATGGTAATAGGTCTTATGCTTGTAGCACCTCA
ATTACCTAATGCTTATGGGGTAGCAGCAGGCACAGAAAGCCCAATATATTTATCAATGCTTGGATTATCAATACCAGTTG
TAGGTTACCAAGGATCTGTATTACCAGCATTAGTTTTAGGAATCATAGCAGCTAAAACTCAAAAGGCACTTAAAAAAGTT
ATACCAGATGTACTTGATTTAATAGTTACTCCTTTTATAACATTATTAGTTTCTATGATACTGGGATTATTAGTTGTTGG
ACCATTAATGCATACAATGGAACTTTGGGTATTTGGAGCAATTAAAGGATTCATGTCACTTCCATTTGGACTAGGTGGAT
TAGTAGTAGGTGGAGTTCATCAAATTATCGTAGTTACTGGAATACATCATGCATTTAGCGCATTAGAAGTTGAACTTTTA
GCAACAACAGGAACTAATGCATTCAACGCAATGATTACTTGTGGAATAGTAGCTCAAGGGGCATCATCAGTAGCAGTTGC
ATTAAAAACAAAAGATAAGAAAAAACGTTCATTATATATTTCATCAGCTATTCCAGCATTCTTAGGAATTACAGAACCAG
CTATATTCGGAATAAACTTAAGATTTATAAAACCATTTGTATTTGGTTGTATAGGTGGAGCAGCAGGTGGCATGCTTGCA
GGAATACTTAAGTTAGCAGGAACAGGAATGGGAATTACAGCTTTTCCAGGTACATTATTATACATGAATAGTTTACCTGG
ATATTTATTAATAAATGGTGTTGCAATGGCTGTTGCATTCTGTTTAACATATTTCTTTTTTAAAACAGAAGAATAA

Upstream 100 bases:

>100_bases
TTCAGTTATATTTTTAAAAGTGTTGACATAGAAATGTGGAACTGATATCATAAATTCATGAAAACGGTTAGCTAGAAAAA
TTAATTAGGAGGAAATGAGT

Downstream 100 bases:

>100_bases
AAATTTAAGATAAAACAATTGTATAGGTTTAGTGAGATTAATTTCTTACTAAATCTATATCATTATATAAAACTATTTAA
AATTTTTCTTATTACACATA

Product: pts system, sucrose-specific iibc component

Products: NA

Alternate protein names: EIIBC-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKEQVVAQEILKSIGGKENIKSIEHCATRLRIILKDKEKINEKSIENIDGVKGQFFAAGQYQVILGTGFVNKVYAQIVNE
SDNLANTSAKEDAYSEMTMLQKISRTFGDVFVPIIPVLVATGLFMGLRGLLQNLGVEMNENFLLFTQVLTDTAFAFLPAL
VAWSTMKKFGGTPVIGMVIGLMLVAPQLPNAYGVAAGTESPIYLSMLGLSIPVVGYQGSVLPALVLGIIAAKTQKALKKV
IPDVLDLIVTPFITLLVSMILGLLVVGPLMHTMELWVFGAIKGFMSLPFGLGGLVVGGVHQIIVVTGIHHAFSALEVELL
ATTGTNAFNAMITCGIVAQGASSVAVALKTKDKKKRSLYISSAIPAFLGITEPAIFGINLRFIKPFVFGCIGGAAGGMLA
GILKLAGTGMGITAFPGTLLYMNSLPGYLLINGVAMAVAFCLTYFFFKTEE

Sequences:

>Translated_451_residues
MKEQVVAQEILKSIGGKENIKSIEHCATRLRIILKDKEKINEKSIENIDGVKGQFFAAGQYQVILGTGFVNKVYAQIVNE
SDNLANTSAKEDAYSEMTMLQKISRTFGDVFVPIIPVLVATGLFMGLRGLLQNLGVEMNENFLLFTQVLTDTAFAFLPAL
VAWSTMKKFGGTPVIGMVIGLMLVAPQLPNAYGVAAGTESPIYLSMLGLSIPVVGYQGSVLPALVLGIIAAKTQKALKKV
IPDVLDLIVTPFITLLVSMILGLLVVGPLMHTMELWVFGAIKGFMSLPFGLGGLVVGGVHQIIVVTGIHHAFSALEVELL
ATTGTNAFNAMITCGIVAQGASSVAVALKTKDKKKRSLYISSAIPAFLGITEPAIFGINLRFIKPFVFGCIGGAAGGMLA
GILKLAGTGMGITAFPGTLLYMNSLPGYLLINGVAMAVAFCLTYFFFKTEE
>Mature_451_residues
MKEQVVAQEILKSIGGKENIKSIEHCATRLRIILKDKEKINEKSIENIDGVKGQFFAAGQYQVILGTGFVNKVYAQIVNE
SDNLANTSAKEDAYSEMTMLQKISRTFGDVFVPIIPVLVATGLFMGLRGLLQNLGVEMNENFLLFTQVLTDTAFAFLPAL
VAWSTMKKFGGTPVIGMVIGLMLVAPQLPNAYGVAAGTESPIYLSMLGLSIPVVGYQGSVLPALVLGIIAAKTQKALKKV
IPDVLDLIVTPFITLLVSMILGLLVVGPLMHTMELWVFGAIKGFMSLPFGLGGLVVGGVHQIIVVTGIHHAFSALEVELL
ATTGTNAFNAMITCGIVAQGASSVAVALKTKDKKKRSLYISSAIPAFLGITEPAIFGINLRFIKPFVFGCIGGAAGGMLA
GILKLAGTGMGITAFPGTLLYMNSLPGYLLINGVAMAVAFCLTYFFFKTEE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=429, Percent_Identity=30.3030303030303, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI1790159, Length=432, Percent_Identity=28.7037037037037, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788769, Length=427, Percent_Identity=28.8056206088993, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI48994906, Length=423, Percent_Identity=27.4231678486998, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 47966; Mature: 47966

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQVVAQEILKSIGGKENIKSIEHCATRLRIILKDKEKINEKSIENIDGVKGQFFAAGQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCHHHHHHCCCCCCCEEECCC
YQVILGTGFVNKVYAQIVNESDNLANTSAKEDAYSEMTMLQKISRTFGDVFVPIIPVLVA
EEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLFMGLRGLLQNLGVEMNENFLLFTQVLTDTAFAFLPALVAWSTMKKFGGTPVIGMVIG
HHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LMLVAPQLPNAYGVAAGTESPIYLSMLGLSIPVVGYQGSVLPALVLGIIAAKTQKALKKV
HHHHCCCCCCCCEECCCCCCCEEEEEHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IPDVLDLIVTPFITLLVSMILGLLVVGPLMHTMELWVFGAIKGFMSLPFGLGGLVVGGVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QIIVVTGIHHAFSALEVELLATTGTNAFNAMITCGIVAQGASSVAVALKTKDKKKRSLYI
HHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEH
SSAIPAFLGITEPAIFGINLRFIKPFVFGCIGGAAGGMLAGILKLAGTGMGITAFPGTLL
HHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHE
YMNSLPGYLLINGVAMAVAFCLTYFFFKTEE
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEQVVAQEILKSIGGKENIKSIEHCATRLRIILKDKEKINEKSIENIDGVKGQFFAAGQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHHCHHHHHHCCCCCCCEEECCC
YQVILGTGFVNKVYAQIVNESDNLANTSAKEDAYSEMTMLQKISRTFGDVFVPIIPVLVA
EEEEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLFMGLRGLLQNLGVEMNENFLLFTQVLTDTAFAFLPALVAWSTMKKFGGTPVIGMVIG
HHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LMLVAPQLPNAYGVAAGTESPIYLSMLGLSIPVVGYQGSVLPALVLGIIAAKTQKALKKV
HHHHCCCCCCCCEECCCCCCCEEEEEHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IPDVLDLIVTPFITLLVSMILGLLVVGPLMHTMELWVFGAIKGFMSLPFGLGGLVVGGVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QIIVVTGIHHAFSALEVELLATTGTNAFNAMITCGIVAQGASSVAVALKTKDKKKRSLYI
HHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEH
SSAIPAFLGITEPAIFGINLRFIKPFVFGCIGGAAGGMLAGILKLAGTGMGITAFPGTLL
HHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHE
YMNSLPGYLLINGVAMAVAFCLTYFFFKTEE
EECCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8628219 [H]