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The map label for this gene is scrR [H]

Identifier: 187934038

GI number: 187934038

Start: 3653562

End: 3654554

Strand: Reverse

Name: scrR [H]

Synonym: CLL_A3457

Alternate gene names: 187934038

Gene position: 3654554-3653562 (Counterclockwise)

Preceding gene: 187934943

Following gene: 187933523

Centisome position: 96.16

GC content: 27.49

Gene sequence:

>993_bases
ATGAAAAGAAAAGTAACGATTCAAGACATTGCGAATATGGTTAATGTATCAAAAAGTAGTGTGTCTAGATATTTAAATAA
TGGATATGTAAGTGAAGAGAAAGCTAAAAAAATACAAGAGGCAATAGAAAAAACAGGTTTTGAAACTAACTTTTTTGCTA
AAAGATTAAAAACTAAAAATAGCAAGTTAATAGGAATAGTGCTTCCAAGAATTGATTCTGTCACAGTTGGAAAGCTATTA
ACAGGAATTAACAGGGTATTAGATAAAAATGATTACCAAGGAATAATCTTAATAAGTGAACTGGATATAGAAAAAGAAAT
TTCTAATATAAACAATTTATATCAACAAGGTGTTGATGGAATAATAATTAATGCTATGGCTATTACTAAGGAACATATAC
AGCTTATAAATAAGTTAAATATACCAATAATGTTTACAGGTCAAAAGAGTTATTATGTTAATTACATGAAAATTGATGAT
TACGAAGCAGGTAAAATTATGGGGAATTACTTTAAAGAAAATGGTCATAAAAGAGTTGTTTTCTTAGGTGTAGATGAATG
GGATATAGCAGTTGGAGTAGATAGAAAAAAAGGTTTTATAGATGAATTTAAAAAGGATAATTTAAATTCAGATGTTAAAT
TTGTAGAGACTGATTTCTCGTTTAAAAAAGCATATGAAAAGGCTAAAGAAGTTGTAGATTATAAACCAACAGCAATAGTT
TGTGCAACTGATAATGTATGTTTAGGGGTACTTAGATACCTTCATGAAAATAATATTAAGGTTCCAGAGGATATTTCTAT
AGCAGGATTTGGAGGATATGATATAGGAAGTGTTTCATATCCAACACTAACAACAGTCGCTTTTGATTATGATCTTATAG
GAGAAAGAACAGCACAAGGCATTTTAGATTTAATAAATGAAAAAGAGATAAATAAAGATGATAATAGTTCATTAAGGTTA
ATTGAAAGAGAAAGTGTAAGAAAAATAACTTAA

Upstream 100 bases:

>100_bases
TTAAAATTTTTCTTATTACACATAAGATAATAGTATTGATAGTATGCAATAATATTATTATAGTTATCATGGAGTTATTA
AAACTTATGTGGAGGATTTT

Downstream 100 bases:

>100_bases
ACAAAAGAGAGGAAAACTATGCAGGATAAAAATGTATACGAAGAAATAAATAAAGATTTAGATCGGTACTATAAAAATTC
AAATAATAGCAAATGGAGGA

Product: sucrose repressor

Products: NA

Alternate protein names: Scr operon regulatory protein [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKRKVTIQDIANMVNVSKSSVSRYLNNGYVSEEKAKKIQEAIEKTGFETNFFAKRLKTKNSKLIGIVLPRIDSVTVGKLL
TGINRVLDKNDYQGIILISELDIEKEISNINNLYQQGVDGIIINAMAITKEHIQLINKLNIPIMFTGQKSYYVNYMKIDD
YEAGKIMGNYFKENGHKRVVFLGVDEWDIAVGVDRKKGFIDEFKKDNLNSDVKFVETDFSFKKAYEKAKEVVDYKPTAIV
CATDNVCLGVLRYLHENNIKVPEDISIAGFGGYDIGSVSYPTLTTVAFDYDLIGERTAQGILDLINEKEINKDDNSSLRL
IERESVRKIT

Sequences:

>Translated_330_residues
MKRKVTIQDIANMVNVSKSSVSRYLNNGYVSEEKAKKIQEAIEKTGFETNFFAKRLKTKNSKLIGIVLPRIDSVTVGKLL
TGINRVLDKNDYQGIILISELDIEKEISNINNLYQQGVDGIIINAMAITKEHIQLINKLNIPIMFTGQKSYYVNYMKIDD
YEAGKIMGNYFKENGHKRVVFLGVDEWDIAVGVDRKKGFIDEFKKDNLNSDVKFVETDFSFKKAYEKAKEVVDYKPTAIV
CATDNVCLGVLRYLHENNIKVPEDISIAGFGGYDIGSVSYPTLTTVAFDYDLIGERTAQGILDLINEKEINKDDNSSLRL
IERESVRKIT
>Mature_330_residues
MKRKVTIQDIANMVNVSKSSVSRYLNNGYVSEEKAKKIQEAIEKTGFETNFFAKRLKTKNSKLIGIVLPRIDSVTVGKLL
TGINRVLDKNDYQGIILISELDIEKEISNINNLYQQGVDGIIINAMAITKEHIQLINKLNIPIMFTGQKSYYVNYMKIDD
YEAGKIMGNYFKENGHKRVVFLGVDEWDIAVGVDRKKGFIDEFKKDNLNSDVKFVETDFSFKKAYEKAKEVVDYKPTAIV
CATDNVCLGVLRYLHENNIKVPEDISIAGFGGYDIGSVSYPTLTTVAFDYDLIGERTAQGILDLINEKEINKDDNSSLRL
IERESVRKIT

Specific function: Negative regulator of scrB expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=26.7295597484277, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=25, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790689, Length=300, Percent_Identity=24.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=24.9211356466877, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790194, Length=298, Percent_Identity=23.489932885906, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=23.9520958083832, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787906, Length=255, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=22.089552238806, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786540, Length=329, Percent_Identity=22.7963525835866, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788474, Length=296, Percent_Identity=25.6756756756757, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=23.1746031746032, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=22.8668941979522, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786268, Length=324, Percent_Identity=21.2962962962963, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789456, Length=326, Percent_Identity=25.4601226993865, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37398; Mature: 37398

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKVTIQDIANMVNVSKSSVSRYLNNGYVSEEKAKKIQEAIEKTGFETNFFAKRLKTKN
CCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SKLIGIVLPRIDSVTVGKLLTGINRVLDKNDYQGIILISELDIEKEISNINNLYQQGVDG
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCE
IIINAMAITKEHIQLINKLNIPIMFTGQKSYYVNYMKIDDYEAGKIMGNYFKENGHKRVV
EEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEE
FLGVDEWDIAVGVDRKKGFIDEFKKDNLNSDVKFVETDFSFKKAYEKAKEVVDYKPTAIV
EEECCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEE
CATDNVCLGVLRYLHENNIKVPEDISIAGFGGYDIGSVSYPTLTTVAFDYDLIGERTAQG
EECCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHH
ILDLINEKEINKDDNSSLRLIERESVRKIT
HHHHHHHHCCCCCCCCCEEEEEHHHHCCCC
>Mature Secondary Structure
MKRKVTIQDIANMVNVSKSSVSRYLNNGYVSEEKAKKIQEAIEKTGFETNFFAKRLKTKN
CCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
SKLIGIVLPRIDSVTVGKLLTGINRVLDKNDYQGIILISELDIEKEISNINNLYQQGVDG
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCE
IIINAMAITKEHIQLINKLNIPIMFTGQKSYYVNYMKIDDYEAGKIMGNYFKENGHKRVV
EEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEE
FLGVDEWDIAVGVDRKKGFIDEFKKDNLNSDVKFVETDFSFKKAYEKAKEVVDYKPTAIV
EEECCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEE
CATDNVCLGVLRYLHENNIKVPEDISIAGFGGYDIGSVSYPTLTTVAFDYDLIGERTAQG
EECCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHH
ILDLINEKEINKDDNSSLRLIERESVRKIT
HHHHHHHHCCCCCCCCCEEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550467 [H]